This article is based on the contribution of human augmentation in creating physical and cognitive improvement. Nowadays it makes a positive impact on the medical sector and technological advancement provides outstanding opportunities to lead a better life. It helps to increase the action of the people and also increase the level of activity. Artificial intelligence helps to improve the facilities of technologies and there are various kinds of sensors, devices, and another sensory mechanism that develop the action of the technologies. This study has focused on the construct between human enhancement and human augmentation. This study has also shed light on several kinds of human augmentation and also focused on the collaboration of humans and machines. It has been discussed that neuromorphic technologies achieved so much attention from scientists and it can be considered as a computing system that can mimic the “neurobiological architecture”. This study has focused on several kinds of several kinds of technologies that can improve the individuals’ difficulties such as artificial limbs, bionics, and other. On the other hand, this study has also elaborated the bonding between machine and collaboration. The “human augmentation” is the combination of biological applications and human beings in the field of medical science. This kind of advancement incorporates with medicines, gene editing, wearable devices and cellular implants. These technological experiments can be implemented on the body of human being and researchers have been working on the area of smart application of drugs to prohibit some serious health complications. These experiments can improve the society as well as make an impact on the people psychology as well. Keywords : Artificial limbs, genetic alteration, HUMAN AUGMENTATION, human-machine collaboration, implementation of chips, neurobiological architecture plastic surgery, Prosthetics.