This paper presents the results of precise measurements of temperature and pore pressure in the “reservoir–well” system during the development of iron ore deposits of the Kursk Magnetic Anomaly (KMA) via blasting. For the observation period from October 2021 to June 2024, variations in compressibility, permeability and temperature in the upper Albian-Cenomanian confined aquifer, which is used for district water supply, were determined. The general trend in a decrease in water temperature was traced (from 12 °C to 11.4 °C). It was accompanied by an increase in the hydrostatic head (from 3.7 m to 7.4 m). Water temperature in the upper aquifer was measured for 9 industrial explosions in the mine and for 30 explosions in the quarry. For one explosion in the mine and five explosions in the quarry the coseismic changes in water temperature with amplitudes of 0.06–0.09 °C were established, while changes in pore pressure in the “reservoir–well” system were 0.4–2.2 kPa. Local changes in the permeability of the reservoir in the vicinity of the well (the skin effect) are considered to be the main factor that controls the coseismic response of temperature during industrial explosions. As the reservoir permeability increases, the water temperature in the “reservoir–well” system can decrease and vice versa. The same pattern was observed according to regime measurements performed in 2022–2023. The recorded coseismic responses of water temperature in the upper aquifer in the high-frequency range are similar to the effects observed during propagation of seismic waves originated from earthquakes in the low-frequency range at different sites all over the world for the seismic energy density of 0.05–0.45 J/m3. The observed variations in aquifer temperature in the “reservoir–well” system under episodic dynamic impacts are of particular interest from the point of view of activating hydrogeochemical processes that accompany the development of iron ore deposits.