In this paper, firstly, we prove an identity involving generalized conformable integrals. By using this obtained identity, we establish several Simpson-type inequalities for differentiable co-ordinated convex function by means of generalized conformable fractional integrals. More precisely, some Simpson-type inequalities are obtained using the well-known Hölder and Power mean inequalities. Furthermore, we also consider some special cases which can be deduced from the main results.