Satellite galaxies can be used to indicate the dynamic mass of galaxy groups and clusters. In this study, we apply the axisymmetric Jeans Anisotropic Multi-Gaussian Expansion (JAM) modeling to satellite galaxies in 28 galaxy clusters selected from the TNG300-1 simulation with halo masses of log10M200/M⊙>14.3 . If using true bound satellites as tracers, the best constrained total mass within the half-mass radius of satellites, M(<r half), and the virial mass, M 200, have average biases of −0.01 and 0.03 dex, with average scatters of 0.11 dex and 0.15 dex. If selecting companions in the redshift space with a line-of-sight depth of 2000 km s−1, the biases are −0.06 and 0.01 dex, while the scatters are 0.12 and 0.18 dex for M(<r half) and M 200. By comparing the best-fitting and actual density profiles, we find that ∼29% of the best-fitting density profiles show very good agreement with the truth, ∼32% display over/underestimates at most of the radial range with biased M(<r half), and 39% show under/overestimates in central regions and over/underestimates in the outskirts, with good constraints on M(<r half); yet most of the best constraints are still consistent with the true profiles within 1σ statistical uncertainties for the three circumstances. Using a mock DESI Bright Galaxy Survey catalog with the effect of fiber incompleteness, we find DESI fiber assignments and the choice of flux limits barely modify the velocity dispersion profiles and are thus unlikely to affect the dynamical modeling outcomes. Our results show that with current and future deep spectroscopic surveys, JAM can be a powerful tool to constrain the underlying density profiles of individual massive galaxy clusters.