Clusters Research Articles

Conditioning a Brownian loop-soup cluster on a portion of its boundary

Dans le present article, nous etudions certaines proprietes des amas de lacets browniens, dans une soupe de lacets browniens d’intensite $c$ dans un domaine du plan, pour toute intensite $c\le 1$. Notre principal resultat dit que si l’on decouvre de maniere Markovienne une portion $\partial $ du bord exterieur d’un tel amas, alors dans le domaine restant, la loi conditionnelle de l’union de tous les lacets dans $L$ qui touchent $\partial $ satisfait la propriete de restriction conforme tandis que les autres lacets dans $L$ forment une soupe de lacets independante. Ceci implique en particulier l’existence d’une transition de phase a $c=14/15$ pour la connectivite de l’ensemble des lacets qui touchent $\partial $. Nos resultats constituent une extension de certains resultats de notre papier (J. Eur. Math. Soc. (2019) to appear) dans les deux directions suivantes: Dans (J. Eur. Math. Soc. (2019) to appear), un cluster de lacets est conditionne par son bord exterieur entier tandis que nous decouvrons ici seulement une partie de ce bord. En outre, dans (J. Eur. Math. Soc. (2019) to appear), nous expliquons que la description que nous donnons de l’ensemble des lacets qui touchent ce bord via un processus ponctuel de Poisson d’excursions est specifique au cas de la soupe de lacets critique ($c=1$), nous montrons ici que dans les cas sous-critiques $c<1$, une propriete plus faible de restriction conforme reste neanmoins vraie.

Methylated clusters

Methylated clusters

Structures and Progress of Carbon Clusters

Structures and Progress of Carbon Clusters

Los parques industriales: estrategias para el fomento de las pymes en las regiones

El objetivo de este trabajo es reflexionar sobre un modelo inclusivo y replicable de los conglomerados de alto nivel de competitividad sistémica, cuyos efectos se centran en el desarrollo sostenible del sector de las pymes, a partir de indagar sobre la competitividad alcanzada por los llamados grupos industriales. A nivel mundial, los parques y áreas industriales representan una planificación estratégica de la producción que impulsa y potencia la generación de la riqueza regional, así como también el mejoramiento de las condiciones socioeconómicas de la población. Asimismo, se pretende: (a) contribuir a evaluar los desafíos que enfrentan las pymes en nuestra región, a medida que se consolida el proceso de globalización económica y (b) proporcionar información de antecedentes sobre el desarrollo de los llamados grupos productivos como estrategia para mejorar la competitividad de estas organizaciones.

Enterovirus Echo 11 Infections in Neonates, Taiwan, 2018

Taiwan Centers for Disease Control detected that enteric cytopathic human orphan virus 11, Echo 11 was prevalent in the community through contract laboratory surveillance in May, 2018. Neonatal cases of Echo 11 infections with severe complications and Echo 11 clusters in neonatal care units of hospitals or nursing homes were also confirmed successively. As of September 14, 2018, a total of 181 Echo 11 cases were detected, showing a significant increase compared with the numbers in 2016 and 2017. Among these 181 cases, 35 were neonates (19.3%); 8 of which were with severe complications. The proportion of neonatal Echo 11 infection with severe complications (22.9%) was higher than other age groups, and the number of cases with severe complications and deaths was also higher than those in previous years, indicating that neonatal Echo 11 infection was associated with a higher risk of severe complications. Echovirus used to cause severe complications or death in newborns. Because the virus can be transmitted through the placenta, birth canal or asymptotic care unit personnel, it is hard to prevent. We recommended strengthening the neonatal and maternal enterovirus infection prevention and protection measures to reduce cases with severe complications and deaths, and strengthening implementation of infection control measures in maternal and neonatal care units to avoid clusters.

Enantioseparation of Au20(PP3)4Cl4 Clusters with Intrinsically Chiral Cores

AbstractAu20(PP3)4Cl4 (PP3=tris(2‐(diphenylphosphino)ethyl) phosphine), abbreviated as Au20, is the only Au nanocluster with an intrinsically chiral core without a chiral environment (chiral ligands or Au‐thiolate staples), making it a unique object to understand chiral evolution and explore chiral applications. Unfortunately, the synthesized Au20 is racemic, and its enantiomers have not yet been separated. Herein, we report a supramolecular assembly strategy with α‐cyclodextrin (α‐CD) to afford enantiopure Au20 in bulk, and an enantiomer excess (ee) value of as‐separated Au20 of 97 %. As a result of its high purity, the distinctive optical activity of Au20, which originates from electronic transitions confined in chiral cores, is fully explored. Theoretical studies reveals that the enantioseparation results from the preferential self‐assembly of α‐CD with organic ligands on the surface of right‐handed Au20.

Ensembling Solutions for Semi – Supervised Clusters

Ensembling Solutions for Semi – Supervised Clusters

Abstract P3-05-18: The complex landscape of breast cancer immune evasion and its implications to personalized and combined immunotherapy

Abstract Cancer immunotherapy activates the patient's immune system to recognize and kill cancer cells. The efficacy of immunotherapy in human breast cancer (BRCA) is hindered by the poor understanding of the immune system's anti-tumor response and tumor evasive mechanisms, and the lack of optimized treatment regimens for each BRCA patient. There are 6 known evasion mechanisms (M) by which tumors can escape immune surveillance. M1: immunosuppression via interleukin 10 (IL-10) and tumor growth factor beta (TGF-β); M2: induction of tolerance by cytotoxic T-lymphocyte associated protein 4 (CTLA-4), programmed cell death protein 1 (PD-1) and its ligands (PD-L1/PD-L2), and interferon gamma (IFN-γ); M3: apoptosis resistance via the expression of anti-apoptotic molecules, namely baculoviral IAP repeat-containing protein 3 (BIRC3), TNF receptor associated factor 1 (TRAF1), and TNF alpha induced protein 3 (TNFAIP3); M4: counterattack via decoy death receptors; M5: impaired antigen presentation by decreasing beta 2 microglobulin (B2M) and human leukocyte antigens A and B expression (HLA-A and HLA-B); and M6: ignorance caused by the absence of a danger signal or an antigen. Yet, which mechanisms or combination of mechanisms BRCA tumors utilize is unknown. Moreover, the currently used biomarkers for the choice of immunotherapy are not ideal, as for example, not all PD-L1+ patients respond to anti-PD-L1 treatment, and certain PD-L1- patients respond. Thus, there is a need for more precise biomarkers. Using the sequential biclustering method on the RNA-sequenced data of BRCA from The Cancer Genome Atlas (TCGA), eighty-one percent of BRCA patients were grouped into 7 different clusters (CL) of immune evasion subtypes. We found that the majority of breast cancer tumors utilize multiple immune evasion mechanisms. Tumors may use from 1 up to 4 combinatorial mechanisms simultaneously. We also identified classifier genes that would help sort patients based on their evasion mechanisms, and guide the choice of immunotherapy. This is especially important since the immune evasion molecules may not be the ideal biomarkers for the best choice of immunotherapy. Moreover, we showed that triple negative breast cancer (TNBC) patients were significantly associated with CL2 (M5). Citation Format: Bou-Dargham MJ, Liu Y, Sang Q-XA, Zhang J. The complex landscape of breast cancer immune evasion and its implications to personalized and combined immunotherapy [abstract]. In: Proceedings of the 2017 San Antonio Breast Cancer Symposium; 2017 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2018;78(4 Suppl):Abstract nr P3-05-18.

DEVELOPMENT TRENDS IN INTELLIGENT HOMES

Since the U.S. National Science and Technology Council began implementing its plans for the development of intelligent structures in 2004, the Taiwan Communications Industry Alliance has been committed to applying communication and monitoring technologies in the construction industry to develop a market for intelligent houses. Accordingly, in this paper, relevant studies from January 2000 to December 2016 were collected from the Web of Science database. A key-route main path analysis of the text and data as well as a growth analysis of the research clusters in this field were performed to determine the main research topics and development trajectories. The development track for intelligent houses involves seven topics, namely general care, application of recognition sensors, energy management, medicine, application of the Internet of things, activity recognition systems, and monitoring technology. This paper offers a valuable literature review and analysis of this field and may acquaint scholars with related industrial development trends and academic progress.

. [Второй, «назально-кластерный»] закон Турнейзена, латинские герундивы, латинские nomina abstracta на ­ō, ­inis и... закон Клуге. Ч. IV. Сочетания с гуттуральными (продолжение)

. [Второй, «назально-кластерный»] закон Турнейзена, латинские герундивы, латинские nomina abstracta на ­ō, ­inis и... закон Клуге. Ч. IV. Сочетания с гуттуральными (продолжение)

Особенности развития российских мусороперерабатывающих кластеров посредством имплементации инструментов проектного управления

Особенности развития российских мусороперерабатывающих кластеров посредством имплементации инструментов проектного управления

An antiferromagnetic metalloring pyrazolate (Pz) framework with [Cu12(μ2-OH)12(Pz)12] nodes for separation of C2H2/CH4 mixture

An antiferromagnetic pyrazolate (Pz) MROF-12 with cyclic-type [Cu12(μ2-OH)12(Pz)12] clusters and new topology of the Schläfli symbol {460.66} was reported for the separation of C2H2/CH4 or CO2/CH4 mixture.

From metric properties to unit-cell databases and clusters

From metric properties to unit-cell databases and clusters

Innovación y competitividad de los clusters de Paraguay: evidencia de las limitaciones

Este artículo tiene por objetivo analizar la posición competitiva de los clusters de Paraguay, identificando sus principales limitaciones. Fueron objetos de investigación los clusters formalizados de siete sectores, ubicados geográficamente en distintas zonas del país. Se ha llevado adelante un estudio comparativo a nivel regional, y en una segunda etapa, un estudio multicasos de los distintos clusters del país, enfocado principalmente a los factores asociados a la competitividad. Los resultados muestran que el nivel de implementación en los siete sectores, se encuadran dentro de la categoría “cluster de sobrevivencia de pequeñas y medianas empresas” y presenta debilidades comunes pronunciadas como la limitada capacidad de innovación, bajo nivel de especialización, integración y cooperación, que influyen directamente en la competitividad de las Pymes agrupadas bajo este modelo de negocio. La incómoda posición en el tablero de la competitividad regional, impone la necesidad de una refundación de los clusters paraguayos.

Гибридные вычислительные кластеры для изучения структуры, функции и регуляции белков

Суплатов Дмитрий Андреевич, к.х.н., с.н.с. НИИ физико-химической биологии имени А.Н. Белозерского, Московский государственный университет имени М.В. Ломоносова (Москва, Российская Федерация). Попова Нина Николаевна, к.ф-м.н., доцент Факультета вычислительной математики и кибернетики, Московский государственный университет имени М.В. Ломоносова (Москва, Российская Федерация). Копылов Кирилл Евгеньевич, студент Химического факультета, Московский государственный университет имени М.В. Ломоносова (Москва, Российская Федерация). Шегай Максим Викторович, аспирант Факультета вычислительной математики и кибернетики, Московский государственный университет имени М.В. Ломоносова (Москва, Российская Федерация). Воеводин Владимир Валентинович, чл.-корр. РАН, д.ф.-м.н., зав. кафедрой супер- компьютеров и квантовой информатики Факультета вычислительной математики и кибернетики, зам. директора Научно-исследовательского вычислительного центра, Московский государственный университет имени М.В. Ломоносова (Москва, Российская Федерация). Швядас Витас Каятоно, д.х.н., профессор Факультета биоинженерии и биоинформатики и НИИ физико-химической биологии имени А.Н. Белозерского, Московский государственный университет имени М.В. Ломоносова (Москва, Российская Федерация). D.A. Suplatov, N.N. Popova, K.E. Kopylov, M.V. Shegay, Vl.V. Voevodin, V.K. Svedas Lomonosov Moscow State University (GSP-1, Leninskie Gory 1, Moscow, 119991 Russia) E-mail: d.a.suplatov@belozersky.msu.ru, popova@cs.msu.su, kopylov@mail.chem.msu.ru, max.shegai@gmail.com, voevodin@parallel.ru, vytas@belozersky.msu.ru

A theoretical study on the geometry and spectroscopic properties of ground-state and local minima isomers of (CuS)n=2-6 clusters

Spectroscopic properties of gas-phase copper sulfide clusters (CuS)n (n = 2–6) are calculated using Density Functional Theory (DFT) and time-dependent (TD) DFT approaches. The energy landscape of the potential energy surface is explored through a basin-hopping DFT methodology. Ground-state and low-lying isomer structures are obtained. The global search was performed at the B3PW91/SDD level of theory. Normal modes are calculated to validate the existence of optimal cluster structures. Energetic properties are obtained for the ground-state and isomer clusters and their relative energies are evaluated for probing isomerization. This is a few tenths of an eV, except for (CuS)2 cluster, which presents energy differences of ∼1 eV. Notable differences in the infrared spectra exist between the ground-state and first isomer structures, even for the (CuS)5 cluster, which has in both configurations a core copper pyramid. TDDFT provides the simulated absorption spectrum, presenting a theoretical description of optical absorption bands in terms of electronic excitations in the UV and visible regions. Results exhibit a significant dependence of the calculated UV/vis spectra on clusters size and shape regarding the ground state structures. Optical absorption is strong in the UV region, and weak or forbidden in the visible region of the spectrum.

De las redes de colaboración para la innovación al desarrollo de clusters de ciencia y tecnología. Dos casos de estudio en la Universidad Nacional de San Martín en Argentina

En este artículo discutimos las políticas orientadas a la promoción de clusters de ciencia y tecnología. En un cluster en formación vinculado a una universidad pública localizada en el conurbano de Buenos Aires, analizamos dos redes de cooperación desarrolladas bajo esquemas diferentes de políticas: bottom-up (kits diagnósticos para salud humana y animal) y top-down (diseño y caracterización de microdispositivos electrónicos). Adoptamos el enfoque de proximidades que permite caracterizar las tensiones entre oportunismo y encerramiento presentes en estas redes de cooperación. La metodología propuesta nos permite comparar cómo la red enfrenta estas tensiones bajo esquemas diferentes. Los resultados muestran que: ante una proximidad organizacional baja, con alto riesgo de oportunismo (bottom-up), la tendenciaes a compensar con mayor proximidad social y mayor estabilidad a partir de usuarios líderes; y ante una proximidad organizacional y tecnológica alta, con riesgo de encerramiento (top-down), la tendencia es de mayor apertura a nuevos usuarios.

A divisive clustering method for functional data with special consideration of outliers

Fil: Justel, Ana. Universidad Autonoma de Madrid; Espana. Universidad Carlos III de Madrid; Espana

Ab initio Molecular Dynamics Simulations on the Structures and Stabilities of Pd Clusters Encapsulated UiO-66 Materials†

Ab initio Molecular Dynamics Simulations on the Structures and Stabilities of Pd Clusters Encapsulated UiO-66 Materials†

Virtualization of Heterogeneous HPC-clusters Based on OpenStack Platform

A.G. Feoktistov, I.A. Sidorov, V.V. Sergeev, R.O. Kostromin, V.G. Bogdanova Matrosov Institute for System Dynamics and Control Theory of SB RAS (Lermontova str., 134, Irkutsk, 664033, Russia) E-mail: agf@icc.ru, ivan.sidorov@icc.ru, vvsergeev@mail.ru, kostromin@icc.ru, bvg@icc.ru. Феоктистов Александр Геннадьевич, к.ф.-м.н., доцент, лаборатория параллельных и распределенных вычислительных систем, Институт динамики систем и теории управления им. В.М. Матросова СО РАН (Иркутск, Российская Федерация) Сидоров Иван Александрович, к.ф.-м.н., доцент, лаборатория параллельных и распределенных вычислительных систем, Институт динамики систем и теории управления им. В.М. Матросова СО РАН (Иркутск, Российская Федерация) Сергеев Вадим Викторович, аспирант, лаборатория параллельных и распределенных вычислительных систем, Институт динамики систем и теории управления им. В.М. Матросова СО РАН (Иркутск, Российская Федерация) Костромин Роман Олегович, аспирант, лаборатория параллельных и распределенных вычислительных систем, Институт динамики систем и теории управления им. В.М. Матросова СО РАН (Иркутск, Российская Федерация) Богданова Вера Геннадьевна, к.ф.-м.н., доцент, лаборатория параллельных и распре деленных вычислительных систем, Институт динамики систем и теории управления им. В.М. Матросова СО РАН (Иркутск, Российская Федерация)