Classic Article Research Articles

Research Trends in Presurgical Infant Orthopaedic Treatment in Patients with Cleft Lip and Palate: A Bibliometric Analysis of 100 Most-Cited Articles.

To assess research trends and publication patterns of literature related to presurgical infant orthopaedics (PSIO) through a bibliometric analysis of the top 100 most-cited articles. The top 100 most-cited articles were identified in the Web of Science (WoS) database using search terms related to PSIO on April 23, 2024, without any restrictions to study design, publication date and language. Standard information about each study was extracted. Citations from WoS, Scopus and PubMed databases were compared. The level of evidence for each article included was assessed. Association between different variables was calculated using Spearman's correlation coefficient with statistical significance set at p < 0.05. Visual analysis of the author's keyword co-occurrence, co-authorship analysis of authors, and citation analysis of journals and authors were performed using VOSviewer. Top cited articles were published from 1994 to 2020, with total individual database citations being WoS (n = 5378), Scopus (n = 6184) and PubMed (n = 10 450). Eleven articles were considered classic articles. Cleft Palate and Craniofacial Journal (Impact Factor = 1.1) had a maximum number of articles and citations. Two hundred eighty-five individuals contributed to top-cited articles, with 62 corresponding authors from 19 countries. A maximum number of authors were affiliated with universities in the United States. The most common keyword used was "nasoalveolar molding (n = 24)", "cleft palate (n = 16)", and "infant orthopedics (n = 16)". The study design of the majority of articles was retrospective and follow-up studies (level 3; n = 53). A weak negative correlation was observed between citation metrics and both the publication year (P < 0.01) and the level of evidence (P < 0.01). This analysis recognises the contributions of experts and offers valuable insights into trends that have shaped the development and evidence related to PSIO research. Future research should focus on integrating advanced technologies, conducting longitudinal studies, fostering collaboration, and emphasizing patient-centred outcomes.

Self-correlated spatial random variables: From an auto- to a sui- model respecification

This paper marks the 50-year publication anniversary of Besag's seminal spatial auto- models paper. His classic article synthesizes generic autoregressive specifications (i.e., a response variable appears on both sides of a regression equation and/or probability function equal sign) for the following six popular random variables: normal, logistic (i.e., Bernoulli), binomial, Poisson, exponential, and gamma. Besag dismisses these last two while recognizing failures of both as well as the more scientifically critical counts-oriented auto-Poisson. His initially unsuccessful subsequent work first attempted to repair them (e.g., pseudo-likelihood estimation), and then successfully revise them within the context of mixed models, formulating a spatially structured random effects term that effectively and efficiently absorbs and accounts for spatial autocorrelation in geospatial data. One remaining weakness of all but the auto-normal is a need to resort to Markov chain Monte Carlo (MCMC) techniques for legitimate estimation purposes. Recently, Griffith succeeded in devising an innovative uniform distribution genre—sui-uniform random variables—that accommodates spatial autocorrelation, too. Its most appealing feature is that, by applying two powerful mathematical statistical theorems (i.e., the probability integral transform, and the quantile function), it redeems Besag's auto- model failures. This paper details conversion of Besag's initial six modified variates, exemplifying them with both simulation experiments and publicly accessible real-world georeferenced data. The principal outcome is valuable spatial statistical advancements, with special reference to Moran eigenvector spatial filtering.

Building the Glucagon-Like Peptide-1 Receptor Brick by Brick: Revisiting a 1993 Diabetes Classic by Thorens etal.

The glucagon-like peptide-1 receptor (GLP-1R) is a class B G protein-coupled receptor involved in the regulation of blood glucose levels and food intake. Stabilized agonists targeting GLP-1R are used in the treatment of type 2 diabetes and have recently become a breakthrough obesity therapy. Here, we revisit a classic article in Diabetes by Thorens etal. that described the cloning, sequencing, and functional expression of the human GLP-1R. The article also demonstrated that exendin4(1-39) was a full agonist of the human GLP-1R whereas exendin4(9-39) was a full antagonist. We discuss how the knowledge imparted by these studies has gone on to inform multiple strands of GLP-1R biology over the past three decades, including pharmacology, signaling, human genetics, structural biology, and chemical biology.

Therapeutic effect of an Ayurvedic drug in the management of Respiratory Allergic Disorders in children - A comprehensive review

Background: Respiratory allergic disorders (RAD) are the most common allergy symptom seen in children. Respiratory allergies are primarily caused by hyper responsiveness of the respiratory mucosa, which results in histamine release and mast cell activation. In Ayurvedic words, this could be viewed as an abnormality of the body's immune system or Ojus induced by disrupted Vata, Kapha, and Pitta. The prevalence of respiratory allergies in school-aged children in India varies widely, ranging from 5-20%. Methods: This study was completed by gathering the knowledge from classical Ayurvedic literature, research articles, guidelines and PubMed and MedLine databases. Results and Discussion: Dashmoola Katutrayadi drug is mentioned in Sahastra Yogam under Swasa Kasahara Kashaya have Shwas-Kasahar, anti-inflammatory, anti-histaminic and anti-asthmatic effects individually and in combinations. Conclusion: Present review reveals that these drugs have potential to alleviate the severity and frequency of RAD and can be used for the management of the same.

Deepana and Pachana - An evaluative analysis

Ayurveda pays utmost importance to Agni as it is the inherent factor behind every change that occurs in the body. The persistent Alpagni is said to be the causative factor for all the diseases. This is why Ama pachana and Agni deepana became the basic line of treatment in many diseases. Detailed and in-depth analysis of various classical references and articles published in reliable web resources has been done on the topic Deepana and Pachana and got some inferences. Pacana has role in conditions of Ama while Deepana in Agnimandya. But in our day to day practice when we have different Oushadha yoga, we can’t discriminate it in the formulations. The range of Deepana and Pachana may vary in each formulation. We may say at the Koshta level Deepana karma improves the Abhyavaharana shakti by stimulating the appetite and Pachana karma improves the Jaranashakthi by improving the digestion.

Nurturing Infants Exploring Ayurveda's Holistic Approach to Care

Abstract Introduction – Ayurveda encompasses a wide range of practices within pediatric care especially plays a pivotal role in nurturing infants by offering safe and effective approaches not only for disease treatment but also for maintaining overall health in this span of age. Acharyas offered their insights on all aspects of newborn and infant care, spanning from birth until the newborn's complete stability. Methods - This study was completed by gathering the knowledge from classical Ayurvedic literature, research articles, guidelines, and PubMed and MedLine databases. Results and Discussion- This study investigates traditional Ayurvedic methods for infant care placing particular attention on evaluating the safety and effectiveness of these practices within the framework of neonatal and infant healthcare upto the age of one year. Conclusion –Kaumarbhritya is seen as the first direct assistance provided by the science of Ayurveda to a newborn upon his debut in this new world, directing him towards a healthy lifestyle in the future and bringing out the finest version of himself. This paper offers an overview of the literary contributions and historical traditional medical practices of healthcare in the domain of Balachikitsa mainly of neonatal and infancy period.The goal is to underscore the significance of research grounded in evidence and its integration into hidden principles concerning neonatal and infant issues described in Ayurveda.

SCOPE OF AYURVEDA IN THE MANAGEMENT OF KUSHTHA (SKIN DISEASES)

Background: Skin disorders are multi-faceted and may have their origin in allergy, autoimmunity, and hereditary. Ayurveda describes skin disorders under the umbrella of Kushtha, a disease characterized by the derangement of the skin. When we take into account the prevalence of different diseases, over 20% of all people seeking medical attention each year are suffering from skin disorders globally. Kushtha is categorized as Maha Kushtha and Kshudra Kushtha by all Acharyas depending on the severity of the symptoms and its prognosis. Many different etiological factors and disease management strategies are described in the Ayurvedic system of medicine. Aim: To assess the scope of Ayurveda in the management of skin diseases. Material &amp; Methods: Different classical Ayurvedic texts, websites, journals and research articles were referred in the above context. Discussion &amp; Conclusion: Kushtha arises from the vitiation of Tridosha and Twak, Rakta, Mamsa and Lasika. Thus the management for Kushtha is based on the involvement of Dosha and Dushya. Though some treatment modalities are condition-specific, the fundamental principle of treatment is consistent with all forms of Kushtha. Acharya have emphasized the significance of Shodhana (detoxification) therapy to eliminate the morbid Dosha from the body, and Raktamokshana to expel Dushita Rakta which is the key Dushya in the pathology of Kushtha. The Shamana (palliative) therapy comprises both internal and external medications viz. Rasa Aushadhi, Churna, Kwath, Asav, Arishta, Guggulu, Ghrita, and Malhara, Tail, Lepa. Dietary management, Dincharya, Ritucharya, Rasayana therapy, and Sadvritta are given immense importance in Ayurveda to preserve good health and prevention of diseases. This wholesome viewpoint of detoxification, palliative care and lifestyle modification needs to be analyzed to develop guidelines for the management of skin diseases based on Ayurveda principles.

Classic publications in food security research: A bibliometric analysis

AbstractThe article presents classic publications in the field of food security from 1993 to 2022 using bibliometric methods. Data come from the Science Citation Index Expanded (SCI‐EXPANDED) of the Web of Science database. The results show that the years 2010 and 2011 stand out as the most prolific, with a total of three classic articles receiving the highest citations. The articles show that agricultural intensification does not necessarily lead to increased yields but rather contributes to environmental degradation through deforestation, biodiversity loss, and ultimately climate change. The articles highlight the adoption of ecologically friendly methods, natural solution, and technology‐based and sustainable agricultural practices to reduce the impact of climate change and address food insecurity. However, linking agricultural intensification to biodiversity conservation and hunger and the effectiveness of different adaptation models in the increasing variability of extreme events remain complex issues that require further research in the future. Similarly, machine learning research can be used to address food insecurity, especially in crop or plant, and forestry tree breeding, precision agriculture, and so forth.

Menelaah Konsep Li’an Suami Sebagai Cara Mencegah Sanksi Menuduh Zina dari Kaca Mata Medis dan HAM Dalam Konteks Kekinian

Background. Li’an is used as an alternative to free a husband from qozhaf sanctions (accusing him of adultery), with the condition that the husband cannot present 4 bayyinah (witnesses) as witnesses to his wife's unfaithful actions. One of the legal consequences of li'an is that it confirms the lineage of a child with its father. Aim. Analyzing the husband's Li’an as a way to prevent sanctions for accusing him of adultery from a medical and human rights perspective Methods. This library research uses a descriptive-qualitative approach. Literature comes from authoritative data, such as classical jurisprudence books, tafsir, articles and books. The data was analyzed qualitatively and presented in descriptive form. Results. DNA test results can be used as evidence of Qorinah (signs), in the category of evidence in the form of allegations. It’s can clarify the child's lineage status, whether it is a child from the mother's husband or from another man, and can also clarify the punishment that will be received by a husband who accuses his wife of infidelity, whether he will be subject to had qozhaf or not. The concept of li’an from a human rights perspective is appropriate, because in li’an there are human rights that must be fought for, namely children's human rights. The state is expected to pay attention to the human rights of li’an children, through regulations that regulate scientific evidence through DNA testing to clarify the status and rights of children.

INSIGHTS INTO BODY DONOR’S ATTITUDES AND PERSPECTIVES; A SURVEY ON VOLUNTARY BODY DONATION

The study delves into the motivations behind voluntary body donation (VBD) by conducting a retrospective analysis of 120 registered body donors at the Department of Rachana Shareera, Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan. The historical context of body donation is explored, tracing its roots back to Hindu religious literature and highlighting key milestones, such as the enactment of the Anatomy Act in India in 1948. The primary aim of the study is to evaluate the reasons driving individuals to voluntarily donate their body after death. The materials include the body donor register and relevant literature from Ayurvedic classical texts, contemporary science, journals, publications, and articles. The methods involve a retrospective analysis of the registered voluntary body donors. The study sheds light on the multifaceted reasons behind voluntary body donation, providing insights that can support educational and awareness initiatives in promoting Voluntary body donation. KEY WORDS: Voluntary Body donation, Body Donors

Understanding Vyana Vayu: Bridging Ayurveda and Modern Physiology

Background: Ayurveda is a traditional system of medicine that is based on the concept of the three doshas - Vata, Pitha, and Kapha, which govern an individual's physical and mental characteristics. Vata dosha serves as the principle driving force within the body. Pitha plays a crucial role in functions such as digestion, metabolism, generating heat, and producing various forms of energy. Kapha is involved in both anabolic processes and maintaining structural integrity of the body. Vata dosha is again divided in to five – prana, udana, samana, vyana and apana vayu. Among these, vyana vayu is mahajava, most powerful and present throughout the entire body. Aim: This review explores the various aspects of vyanu vayu in context of modern physiology. Materials and methods: A comprehensive search for relevant information on Vyana vayu was done by reviewing classical texts and research articles. Conclusion: Vyana vayu assumes a vital role in the coordination and regulation of a range of physiological processes. It holds significant responsibility in overseeing the proper circulation of nutrients, and information throughout the body, primarily within the circulatory and nervous systems. The comprehension of Vyana vayu in contemporary physiology offers valuable insights into the interrelated nature of bodily functions. Acknowledging its influence may have meaningful implications for health and well-being, potentially enhancing the holistic approach to healthcare.

Gratitude, freedom and refusal

ABSTRACT This paper is an exploration of gratitude as a fundamental concept in psychoanalysis. Melanie Klein’s classic article “Envy and Gratitude” (1957) named gratitude at one pole on an axis of human suffering and flourishing, but with a few notable exceptions, the article stimulated research into envy. This paper explores the historical and philosophical traditions that have, to some extent unconsciously, influenced our contemporary understandings of gratitude. The paper also works to explore the social and ethical meanings of gratitude as well as gratitude’s psychoanalytic significance. The aim is to uncover the overall psychic significance of gratitude and its place in human flourishing.

Exploring vital pulp Therapies: A bibliometric analysis of the most cited articles

AimThe aim of this study was to identify and analyze the most cited articles on vital pulp therapies. MethodologyBibliographical data related to the abstract, citations, keywords, and other relevant information was extracted using different combinations of keywords. Further evaluation and visualization of the selected data were performed with the help of various tools, including MS Excel, Microsoft Word, Google open refine, BibExcel, and VOS viewer. An initial search revealed 91 documents, of which 40 were chosen for further analysis. We used the Kolmogorov–Smirnov test and Spearman correlation coefficient test, and our adopted significance level was p < 0.05. ResultsIn total, the articles received 1,905 citations, with six of them receiving at least 100 citations. Among the top 40 articles, the United States of America (10 articles) and Ireland (6 articles) were the countries with the highest number of cited articles. The journals “Journal of Endodontics” (14 articles; 650 citations) and “International Endodontic Journal” (13 articles; 577 citations) published most of the articles among the 50 most cited ones. Duncan H. was the author with the highest number of works cited (11 articles; 339 citations). Of the articles, systematic reviews accounted for 32%, literature reviews for 14%, in vitro experimental studies for 12%, clinical trials for 8%. Among the biomaterials used in vital pulp therapies, mineral trioxide aggregate (MTA) was discussed in 37 articles (74%), followed by calcium hydroxide, mentioned in 30 studies (60%). Interestingly, the publication year did not demonstrate a significant impact on citation count. ConclusionThe present study provided a detailed list of the top 50 most cited and classic articles on vital pulp therapies. This will help researchers, students, and clinicians in the field of endodontics with an impressive source of information.

Ahara Vidhi Vidhana: Ayurvedic Concepts of Food Consumption and Their Relevance in the Modern Age

In the modern world, when everyone is focused on attaining their goals, people often forget their balanced dietary routines, which leads to a number of lifestyle disorders. The three basic pillars of Ayurveda are Ahara, Nidra and Brahmacharya Among these, Ahara has been placed first which shows it is important to maintain and sustain life. Food habits like excessive intake, high protein diet, spicy, oily, harmful combination together, taking food without analysing one’s Agnibala are leading causes for diseases. For achieving complete benefits of food, one should also follow certain rules as told in Ayurveda regarding what, when, where, and how the food should be consumed. In Vimansthana, Charakacharya explains about Aharavidhividhana are the foundation of dietetics, which indicates the method of taking Ahara, which is useful for mankind. Aim &amp; Objectives – To elaborate such principle of Ayurveda known as Ahara Vidhi Vidhan and their relevance in the modern age. Materials and Methods - Different classical Ayurvedic texts, websites, journals and research articles were referred in above context. Discussion and conclusion - The time, place, quantity and manner of Ahara intake are necessary. Ahara taken in proper manner helps in the proper growth of the body on contrary if taken in improper manner leads to various diseases. Thus, Aharavidhividhana plays a significant task in both causation and curing of the disease. Nidanaparivarjana is considered to be the main line of treatment. Properly followed Aharavidhividhana keeps the body healthy and prevents the diseases.

FAIR digital objects for academic publishers

For 200 years, collective scholarly knowledge was advanced by reporting new findings in the form of narrative text that is rich in logic, pinned to data, hedged with cautious nuance, and yielding novel claims. Authors' narratives evolved over the years into the now familiar academic research article, whose form has radiated into thousands of specialized intellectual niches (i.e., journal titles). In the last decades the corpus of collective scholarly knowledge (both narrative text and published data) has come to exceed human comprehension and challenges the ability of researchers, even those working in narrowly defined disciplines, to keep up. As a response, a wide range of abstracting and indexing services emerged and were among the first to push toward “electronic” publishing. By now, articles are routinely made available in digital repositories, but still the content and the form remain bound to human readers while the powerful information processing capabilities of machines, which ought to assist the researcher, are marginalized to the mundane calculation of impact scores. Today, the long-form narrative and the lack of standards in the academic publishing industry make the bulk of this information notoriously difficult for the machine process and reuse in scientific applications. As such, the classical research article has become increasingly untenable as a meaningful unit of intellectual progress. Since 2016, the FAIR Principles have provided guidance on how to compose data, including information contained in narrative text, to make them machine actionable. Recent developments in FAIR Digital Objects are now being exploited in academic publishing to expose FAIR information at the source, avoiding cumbersome text mining, and making exact meaning available to machine assistants supporting human scholars. Here I describe some of these long-term developments and how they relate to a new Sage/IOS Press journal called FAIR Connect. These trends signal an inevitable movement towards the FAIRifcation of scholarship, and hint at key issues that will impact the practice and business of academic publishing.

More than a metaphor: ‘climate colonialism’ in perspective

In early 2022, over 30 years after the Intergovernmental Panel on Climate Change (IPCC) released its first report on the challenges posed by climate change and four subsequent Assessment Reports later, the word ‘colonialism’ finally entered its official lexicon. The sixth report on ‘Impacts, Adaptation and Vulnerability’ references colonialism, not only as a historical driver of the climate crisis, but also as something that continues to exacerbate the vulnerabilities of communities to it (IPCC, 2022). As Funes (2022) argues, this comes in the wake of long-standing arguments made by Indigenous groups and others on the frontline of climate change about the centrality of colonialism to comprehending and responding to the crisis. The last decade has also seen a significant increase in scholarly literature that draws explicit links between colonialism and climate change – much of which is referenced in the latest IPCC report. While formal acknowledgement of this relationship is long overdue, in this article we argue for caution and precision in the invocation of colonialism within these debates. Following Tuck and Yang’s (2012) classic article setting out why ‘decolonization is not a metaphor’, we argue relatedly that colonialism needs to be understood as more than a metaphor in climate change debates.

Journey through the history of Journal of Experimental Biology: a timeline.

In the cut-throat industry of academic publishing, some journals barely survive a decade, let alone a century, but in October 2023, Journal of Experimental Biology is celebrating 100 years at the forefront of comparative physiology, neuroethology and biomechanics. In this Commentary article and the accompanying poster, I explore the journal's history from its inception, through the guidance of nine Editors-in-Chief, to achieving its aims of championing the comparative approach, disseminating and promoting high-quality research and supporting our community of researchers. I discuss technological developments in publishing and classic articles that have cemented the journal in its position at the forefront of comparative physiology.

Top 100 cited classical articles in sentinel lymph nodes biopsy for breast cancer.

The sentinel lymph node biopsy (SLNB) takes on a critical significance in breast cancer surgery since it is the gold standard for assessing axillary lymph node (ALN) metastasis and determining whether to perform axillary lymph node dissection (ALND). A bibliometric analysis is beneficial to visualize characteristics and hotspots in the field of sentinel lymph nodes (SLNs), and it is conducive to summarizing the important themes in the field to provide more insights into SLNs and facilitate the management of SLNs. Search terms relating to SLNs were aggregated and searched in the Web of Science core collection database to identify the top 100 most cited articles. Bibliometric tools were employed to identify and analyze publications for annual article volume, authors, countries, institutions, keywords, as well as hotspot topics. The period was from 1998 to 2018. The total number of citations ranged from 160 to 1925. LANCET ONCOLOGY and JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION were the top two journals in which the above articles were published. Giuliano, AE was the author with the highest number of articles in this field with 15. EUROPEAN INST ONCOL is the institution with the highest number of publications, with 35 articles. Hotspots include the following 4 topics, false-negative SLNs after neoadjuvant chemotherapy; prediction of metastatic SLNs; quality of life and postoperative complications; and lymphography of SLNs. This study applies bibliometric tools to analyze the most influential literature, the top 100 cited articles in the field of SLNB, to provide researchers and physicians with research priorities and hotspots.

Review of Burkhart and DeBeer's (2000) article on traumatic glenohumeral bone defects and their relationship to failure of arthroscopic Bankart repair: Where have we taken the concept of glenoid bone loss in 2023?

This classic discusses the original publication by Burkhart and DeBeer “Traumatic Glenohumeral Bone Defects and Their Relationship to Failure of Arthroscopic Bankart Repair” published in 2000 in Arthroscopy. At that time, the authors sought to understand the reasons behind the failure of arthroscopic soft tissue repair. Based on their findings, the authors introduced the concept of the inverted pear glenoid and engaging Hill-Sachs lesion which is now part of the orthopedic lexicon. The importance of bony pathologic changes in anterior glenohumeral instability has become so apparent, that it now forms the basis of clinical understanding and underpins treatment algorithms. Since this publication over 20 years ago, the idea of glenohumeral bone loss has been extensively explored and refined. There is no doubt of the importance of structural bone loss yet there is still uncertainty as to the best management of those with subcritical bone loss. The purpose of revisiting this classic article is to look at where we are in understanding recurrent instability and bony deficiency while appreciating how far we have come.This review begins with a detailed summary of the classic article along with a historic perspective. Next, we look at the current evidence as it pertains to the classic article and how modern technology and innovation has advanced our ability to assess and quantify glenohumeral bone loss. We finish with expert commentary on the topic from two current surgeons with a research interest in shoulder instability to offer an insight into how modern surgeons view and address this issue. One of the original authors also reflects on the topic. The findings of this classic study changed the way we think about shoulder instability and opened the doors to an exciting body of research that is still growing today. Future research offers an opportunity for high quality evidence to guide management in the group of patients with subcritical bone loss and we eagerly await the results.

A Bibliometric and Scientific Knowledge Map Study of Migraine Treatment from 2013 to 2022.

Migraine treatment research has made much great progress over the past decade. However, there have been few bibliometric studies conducted so far. In this study, bibliometric analysis was used to explore the current status and future trends of migraine treatment research. Migraine treatment-related articles were retrieved from the Web of Science Core Collection on December 7, 2022. Quantitative variables were analyzed by the R-tool bibliometrix and Excel 2020. VOS viewer and CiteSpace software were used to visualize citation, co-authorship, co-occurrence, and co-citation analysis of countries/regions, organizations, authors, references, and keywords. A total of 3294 articles were included with the global publication output showing a slow upward trend. The United States was the most productive country with 1116 papers and gained the most citations. Albert Einstein College of Medicine was the most active institution with 176 papers. Headache published the most articles in this domain, while Cephalalgia was the most commonly co-cited journal. Lipton, RB published the most articles and had the most citations. Tepper S, 2017, Lancet neurology and Silberstein S, 2004, Cephalalgia were defined as classic articles. The current research mainly focuses on CGRP-related therapeutics, such as fremanezumab, erenumab and ubrogepant. Based on the analysis of bibliometric data on migraine treatment over the past decade, the trends and the knowledge graph of the country, organization, author, reference, and the keyword were identified, providing accurate and quick positioning of the critical information in the domain.