The analysis of development projects and reconstruction safe urban environment adopted in recent years, the General plans of the cities of Central Russia from the position of the biosphere compatible technologies. The analysis is based on the fundamental principles of transformation of the city into biosphere compatible and developing the person. It is shown that all the problems of the modern city are between the two extremes – the destruction of nature and degradation of human development level. The algorithm of analysis of master plans and development programs of the city with the quantitative assessment of conceptual bases of formation of safe and comfortable urban environment and approaches to the modelling and forecasting of socio-bio-technosphere in the context of modern challenges and the dynamics of changes in anthropogenic and natural landscapes. It is shown that identified in the draft master plans of the individual cities of Russia the reconstruction of the building of urban infrastructure are not backed by real programs of self-development of their territories. In the doctrine of urban renewal is not the main – the creation of conditions and mechanisms for symbiotic creative development of the city and of man is based on the duality of the problem "man and biosphere". Evidence-based principles for the transformation of the city in biospherically and development of man in the absence of mechanisms for their implementation in real life, in the most part manifests itself negatively. The principle of the symbiosis of city and nature "biosphere compatibility of the city" is uncontested for human survival, and the principle of satisfaction of human needs, including the enforcement of city application functions in any size city or settlement is a priority for human development as an intellectual community.