Due to the uncertainty of the formation and the complexity of downhole tubular string loads and deformations, the existing tubular string static theory is difficult to explain and lacks support from measured data of tubular string dynamic loads. Therefore, a dynamic loads monitor for oil and gas tubular string is developed, which can synchronously measure the internal pressure, external pressure, axial force, and vibration acceleration for the string during the whole operation process. The monitor realizes simultaneous monitoring of tubular string load and vibration response parameters while meeting the requirements of various sensor placement spaces and structural strength safety, simplifying the on-site test process. By adding a power control circuit to the circuit system, the working time of the monitor is extended. The high temperature calibration test of the monitor is carried out, and the maximum calibration error is 0.10%, which meets the requirements of measurement accuracy.