Chronic Mental Disorders Research Articles

DEVELOPMENT OF A CLINICAL GUIDELINE FOR FAMILY-CENTERED COLLABORATIVE CARE IN PATIENTS WITH CHRONIC MENTAL DISORDERS

Introduction: BackgroundChronic mental illnesses have long periods, are recurring, and require continuous care and, becoming chronic, they double the problems of patients and their family. The study’s purpose is, thus, the development of guidelines for family-centered collaborative care of patients with chronic mental illnesses referring to the medical centers (1).MethodsThis mixed methods study is based on the stages of the guideline adaptation provided by the Guidelines International Network (2).ResultsAfter reviewing and gathering evidence from a qualitative study on key participants and reviewing the literature, which includes a search for articles related to participatory family-centered care of patients with chronic mental disorders and a review of available books, a clinical guide Related and upstream documents of the country were 531 recommendations were extracted and sent to a panel of experts for evaluation.ConclusionProviding a family-centered collaborative care guideline will improve the quality of life of these individuals and their families, improve the quality of care, and reduce fragmented health care(3,4).ObjectivesDevelopment of a clinical guideline for family-centered collaborative care in patients with chronic mental disordersMethods: This mixed methods study is based on the stages of the guideline adaptation provided by the Guidelines International Network .ResultsAfter reviewing and gathering evidence from a qualitative study on key participants and reviewing the literature, which includes a search for articles related to participatory family-centered care of patients with chronic mental disorders and a review of available books, a clinical guide Related and upstream documents of the country were 531 recommendations were extracted and sent to a panel of experts for evaluation.ConclusionsProviding a family-centered collaborative care guideline will improve the quality of life of these individuals and their families, improve the quality of care, and reduce fragmented health careReference(s)1) Vigo D, Thornicroft G, Atun R. 2016,Estimating the true global burden of mental illness. The Lancet Psychiatry.3(2):171-8.2) GIN. 2010, guideline Adaptation a source toolkit guideline international network; 953) Molu NG, Ozkan B, Icel S. 2016,Quality of life for chronic psychiatric illnesses and home care. Pakistan journal of medical sciences.32(2):511-54) WHO. 2014, Integrating the response to mental disorders and other chronic diseases in health care systems. Geneva, Switzerland: World Health Organization; 50 pDisclosure of InterestNone Declared

Letter to the Editor in response to the recently published article “Roncero C, Buch B, Martin-Sanchez AM, et al. Prevalence of hepatitis C virus infection in patients with chronic mental disorders: the relevance of dual diagnosis. Gastroenterol Hepatol. 2022”

Letter to the Editor in response to the recently published article “Roncero C, Buch B, Martin-Sanchez AM, et al. Prevalence of hepatitis C virus infection in patients with chronic mental disorders: the relevance of dual diagnosis. Gastroenterol Hepatol. 2022”

Prevalence of hepatitis C virus infection in patients with chronic mental disorders: The relevance of dual disorders

Prevalence of hepatitis C virus infection in patients with chronic mental disorders: The relevance of dual disorders

Moroccan suicidal schizophrenics: Case study in arrazi hospital of sale

IntroductionSchizophrenia is a severe, common, chronic mental disorder with a prolonged and disabling course, having a high social impact.Mortality is two to three times higher in schizophrenic patients than in the general population.Suicide is the main cause of death in patients with schizophrenia. In spite of great efforts in preventing such deaths, suicide rates have remained alarmingly high, highlighting the need for a better understanding of the phenomenon.ObjectivesThe objective of this work is to determine the prevalence of suicide in schizophrenic patients, to investigate the main risk factors in these patients and the characteristics of suicide and the therapeutic management of the patients.MethodsThis is a retrospective study on medical records about 43 patients (32 men / 11 women) who were admitted to the Arrazi Hospital in Salé, from september 2021 to september 2022, using an operating form grouping socio-demographic criteria of the patients, personal and family history, characteristics of the suicide attempt and management.ResultsIn this study, 75% were male and 25% were female with an average age of 34.5 years. The existence of a personal history of suicidal ideation, plans and attempts is a major risk factor for suicide. The lethality of the means used reflects a higher degree of suicidal intentionality. Clozapine, in particular, plays a protective role by reducing the rate of suicides and suicide attempts.ConclusionsDespite therapeutic progress, the prevalence of suicide among patients suffering from schizophrenia is still high.The prevention of suicide in these patients remains fundamental, as does the reduction of positive or negative symptoms, the improvement of quality of life, the reduction of the handicap caused by this illness and the fight against the stigmatization of patients.Disclosure of InterestNone Declared

Osteopenia and osteoporosis associated with hyperprolactinemic antipsychotics

IntroductionThe main role of prolactin is associated mainly with lactogenesis but additionally it participates in several endocrinological and metabolic processes. The prolactin level may be increased with some antipsychotics such as risperidone, paliperidone, and amisulpride increasing the risk of Bone Mineral Mass (BMM) decrease leading to osteopenia and osteoporosis.ObjectivesTo determine the loss of BMM associated with antipsychotic-related iatrogenic hyperprolactinemia (iHPRL) in a sample of patients suffering of chronic psychotic mental disorder and treated with antipsychotics at least for one year.MethodsA cross-sectional observational and epidemiological study in a sample of 140 patients (males 56.9%; females 43.1%; mean age 48 years), receiving antipsychotics was carried out. After giving informed consent, personal data, prolactin level, antipsychotic use and lifestyle were collected. An evaluation of BMM with a central DEXA Scan was performed. The bone mineral density considering the subject´s age and the peak bone mass in the neck of the femur, hip and in the lumbar vertebrae (L1-L4) was obtained. Inclusion criteria: presence of psychotic disorder, age between 18-65 years and treatment with an antipsychotic at least for one year. Statistical analysis was carried out using the statistical software SPSS version 26.0. A significance level α=0.05 was considered throughout the study.Results45 out of 140 patients (32,13%) had some BMM lost (osteopenia). The prevalence of osteoporosis was 5.71% (n=8). The median prolactin level in the sample was 46.1 ng/dL ± 33.1. Patients with hyperprolactinaemia showed a higher frequency of osteopenia/osteoporosis (50% with mild iHPRL and 48% with moderate/severe iHPRL) than those with normal prolactin levels (25.7%). A strong and significant relationship between the presence of osteoporosis and the treatment with risperidone was found (p=0.007).ConclusionsOsteopenia and osteoporosis are associated with hyperprolactinemic antipsychotic. Risperidone was related with a significant increased osteoporosis risk. The rutinary and systematic control of the BMM is crucial in these patients to avoid progressive bone demineralization. Managing strategies should be individualized to avoid bone demineralization and to preserve physical health.Disclosure of InterestNone Declared

Mindfulness, Attention, and Impulsivity in Bipolar Disorder

IntroductionBipolar disorder (BD) is a chronic mental disorder characterized by mood instability1. BD is further related to neurocognitive and functional disruptions that remain remarkably stable even when patients are euthymic, leading to poor well-being and quality of life. Mindfulness means paying attention on purpose, in the present moment, and involves different facets such as observing, describing, acting with awareness, non-judging and non-reacting of inner experience. It remains unclear whether mindfulness and its specific facets are differentially associated with different aspects of attention and trait impulsivity in individuals with BD.ObjectivesTo examine associations between different mindfulness facets, and different aspects of attention and trait impulsivity in BD.MethodsThis study was approved by the Hospital Clínic Ethics and Research Board (HCB/2017/0432). After informed consent, 94 outpatients, M age = 45.57, SD = 9.8, range 19-61 years, 41.5% Male, 63.8% BD-I according to DSM-5 criteria, in partial or total remission based on Young Mania Rating Scale (YMRS; M = 1.81, SD = 2.11) and Hamilton Depression Rating Scale (HDRS; M = 5.46, SD = 3.71) were enrolled in this study. Participants were evaluated using the Five Facet Mindfulness Questionnaire (FFMQ) to assess Mindfulness, the Trail Making Test (TMT-A) and the Conner’s Continuous Performance test (CPT-II) to assess Attention, and the Barratt Impulsiveness Scale (BIS-11) to assess Impulsivity. Pearson correlations were performed, and statistical significance was evaluated two-sided at the 5% threshold.ResultsMindfulness-Describing was negatively associated with Cognitive and Non-Planning Impulsivity (r = -.43 and -.28, p < .001), Mindfulness-Acting with Awareness was negatively associated with Cognitive, Motor and Non-Planning Impulsivity (r = -.27 to -.45, p < .001), Mindfulness Non-Judging (r = -.33 and -.34, p < .001) and Non-Reacting (r = -.30 and -.46, p < .001) of inner experience were negatively associated with Cognitive and Motor Impulsivity. No associations were found between neither Mindfulness nor Impulsivity with any aspects of Attention.ConclusionsPreliminary findings suggest that better performance in specific facets of mindfulness (describing, acting with awareness, non-judging or reacting of inner experience) may be related to a decrease in different aspects of trait impulsivity. Further longitudinal and interventional research is needed on underlying mechanisms. Nonetheless, our study suggests the need for including mindfulness-based approaches to improve behavioral and functional outcomes for those with BD.FundingThis work was supported by the European Union Horizon 2020 research and innovation program (EU.3.1.3. Treating and managing disease: Grant 945151), CIBERSAM, FIS PI17/00941 ISCIII, European Regional Development Fund.

Obsessive-compulsive symptoms in patient with schizophrenia: The influence of disorganized symptoms, duration of schizophrenia, and drug resistance.

Schizophrenia is a chronic mental disorder with a many-faced clinical presentation. Obsessive-compulsive symptoms are often part of it. The characteristics of the clinical picture and the course of schizophrenia are factors related to both the resistance and the manifestation of obsessive-compulsive symptoms. Our study aims to establish the relationship between the peculiarities of the schizophrenia process and the influence of resistance on the expression of obsessive-compulsive symptoms. A study was conducted on 105 patients with schizophrenia. Of them, 39 are men and 66 are women. The evaluation of the effectiveness of the treatment showed that 45 were resistant to the applied therapy, while the remaining 60 responded. Clinical assessment of patients was performed using the Positive and Negative Syndrome Scale (PANSS) and Brief Psychiatric Rating Scale (BPRS). Assessment of obsessive-compulsive symptoms (OCS) was conducted with the Dimensional obsessive-compulsive symptoms scale (DOCS). In 34% of all patients, we found clinically expressed obsessive-compulsive symptoms. In 40% of the patients with resistance, we found clinically expressed obsessive-compulsive symptoms, which are within the range of moderately expressed. In 30% of the patients in clinical remission, we found obsessive-compulsive symptoms, but mildly expressed. We found a statistically significant relationship between the severity of OCS and the disorganized symptoms and the duration of the schizophrenia process. No differences were found in the expression of OCS in patients of both sexes. We registered both an increased frequency and an increased expression of obsessive-compulsive symptoms in patients with resistant schizophrenia. These symptoms were positively associated with disorganized symptoms and duration of schizophrenia. No relationship was established with the positive, negative symptoms, as well as with the gender distribution.

Sex differences in chronic pain-induced mental disorders: Mechanisms of cerebral circuitry.

Mental disorders such as anxiety and depression induced by chronic pain are common in clinical practice, and there are significant sex differences in their epidemiology. However, the circuit mechanism of this difference has not been fully studied, as preclinical studies have traditionally excluded female rodents. Recently, this oversight has begun to be resolved and studies including male and female rodents are revealing sex differences in the neurobiological processes behind mental disorder features. This paper reviews the structural functions involved in the injury perception circuit and advanced emotional cortex circuit. In addition, we also summarize the latest breakthroughs and insights into sex differences in neuromodulation through endogenous dopamine, 5-hydroxytryptamine, GABAergic inhibition, norepinephrine, and peptide pathways like oxytocin, as well as their receptors. By comparing sex differences, we hope to identify new therapeutic targets to offer safer and more effective treatments.

A Framework of Intelligent Mental Health Monitoring in Smart Cities and Societies

In any smart city and society, the citizens’ mental health is one of the utmost concerns. Nowadays, people from different sectors of face a severe mental health threat due to the prolonged pandemic of COVID-19. Depression, anxiety, suicidal behaviours, and post-traumatic stress disorder are widespread terms nowadays for students, health care workers, jobless people, etc. Machine Learning (ML), image processing, expert systems, Internet of Things (IoT) are performing an essential function in the significant acceleration of the automation process within the healthcare industry. This article aims to address the problem of preventing mental health disorders by early predicting individuals using the developed web portal “Mind Turner”; and by integrating the mentioned emerging tools in this way, later chronic mental health disorders can be avoided. We used the Random Forest Classifier to detect stress levels from the Question-Answer-based assessment, and SVM is used to detect facial emotions. Finally, both are combined using Interval Type-2 Fuzzy Logic to predict the probable mental health of a person, i.e. acute depression, moderate depression and not depressed.

Perceived social support and family members of patients with mental disorders: A mixed method study.

Family members are the caregivers to patients with mental disorders at home, and the mental and spiritual pressures caused by this responsibility necessitate physical, mental, and perceived social support for these families. The present mixed method study is an attempt to elaborate on the perceived social support by Iranian families of patients with chronic mental disorders. Using a sequential mixed method explanatory study (quantitative and qualitative), 200 family members of patients with chronic mental disorders were selected through convenient sampling (quantitative phase). Data gathering was started using a demographics form and Stewart and Sherburne's perceived social support scale. The qualitative phase included 10 participants who obtained low scores in the quantitative phase and took part in private, face-to-face, in-depth, and semi-structured interviews. The data obtained in the quantitative phase were analyzed using statistical tests, and the interviews were analyzed using qualitative content analysis. The perceived social support by the participants was at a moderate level in different fields of tangible support, information and emotional support, kindness, and positive social interactions. The results of the qualitative phase revealed social support status in 15 subcategories, 6 categories, and 2 themes of support and acceptance by family, relatives, and friends, with support and being understood by society. The results of the qualitative and quantitative sections emphasized the needs of the patient's family members (who acted as caregivers for patients) for support in family, social, and emotional areas. The family members of patients with chronic mental disorders have different needs in the area of perceived social support. Such needs are more tangible in family members such as children with mentally ill parents or parents with mentally ill children. The results of this study can be used for educational and supportive planning for caregivers of patients, most of whom are family members.

Holistic assessment of patients with chronic mental disorders who attend a metabolic clinic in Sligo Town catchment area.

People with serious mental illness exhibit higher morbidity and mortality rates of chronic diseases than the general population. The aim of this study was to establish a dedicated clinic for patients with chronic mental illness to monitor physical health and quality of life in accordance with best practice guidelines. Patients were invited to attend the clinic. The following areas were examined: personal and family history of cardiovascular disease, diet, exercise, and smoking. Mental state examination, waist circumference, BP, pulse, ECG and BMI. Laboratory tests including U + E, LFTs, HbA1c, Lipid profile and other tests as appropriate such as serum lithium. AIMS scale, HoNOS and WHOQOL-BREF scales as additional indicators of global health. A total of 80 patients attended during 3.5years of clinic. Mean age was 54.9years (SD: 13.81) at first contact and 45% were females. Mean years in the service was 19.66 (SD: 11.54) and mean number of previous hospital admissions was 4.4 (SD: 5.63). Metabolic syndrome was present in 42% at first assessment. A statistically significant improvement was found for the psychological domain of the WHOQOL-BREF and the HoNOs, particularly at third assessment. (β = 4.64, Wald x2 = 7.38, df:1, p = 0.007, CI:1.3-8.1, β = - .889, Wald x2 = 4.08, df:1, p = 0.043, CI: - 1.752 to - .026) respectively. The results show a high prevalence of physical health conditions in this cohort, some of which represent a new diagnosis. This implicates better allocation of existing resources for screening and early detection, and potential to run joint clinics with primary care.

Assessing the association of coffee consumption on the relationship of chronic pain with depression and anxiety

ABSTRACT Background A bidirectional relationship between chronic pain (CP) and mental disorders has been reported, and coffee was believed to be associated with both. However, the association of coffee in this bidirectional relationship remains unclear. We aim to analyze the association of coffee consumption on the relationship of CP with depression and anxiety. Methods A total of 376,813 participants from UK Biobank were included. We collected data on anxiety, depression and CP from objects of our study population. The association of coffee consumption on the relationship of CP with depression and anxiety was assessed through logistic/linear regression models. Moreover, seemingly unrelated estimation test (SUEST) was used to compare whether the coefficients differed in two different groups. Results We observed significant associations of coffee consumption in the interaction of CP with depression and anxiety, such as the association of multisite chronic pain (MCP) on self-reported depression (βcoffee = 0.421, βnon-coffee = 0.488, PSUEST = 0.001), and the association of MCP on generalized anxiety disorder-7 (GAD-7) scores (βcoffee = 0.561, βnon-coffee = 0.678, PSUEST = 0.004) were significantly different between coffee drinking and non-coffee drinking groups. Furthermore, in analysis stratified by gender, we found headache (βmale = 0.392, βfemale = 0.214, PSUEST = 0.022) and hip pain (βmale = 0.480, βfemale = 0.191, PSUEST = 0.021) had significant associations with self-reported depression between males and females groups in coffee drinkers. Conclusions Our results suggested that coffee consumption has a significant association on the relationship of CP with depression and anxiety.

Higher stress response and altered quality of life in schizophrenia patients with low membrane levels of docosahexaenoic acid.

Schizophrenia is a severe, chronic, and heterogeneous mental disorder that affects approximately 1% of the world population. Ongoing research aims at clustering schizophrenia heterogeneity into various "biotypes" to identify subgroups of individuals displaying homogeneous symptoms, etiopathogenesis, prognosis, and treatment response. The present study is in line with this approach and focuses on a biotype partly characterized by a specific membrane lipid composition. We have examined clinical and biological data of patients with stabilized schizophrenia, including the fatty acid content of their erythrocyte membranes, in particular the omega-3 docosahexaenoic acid (DHA). Two groups of patients of similar size were identified: the DHA- group (N = 19) with a lower proportion of membrane DHA as compared to the norm in the general population, and the DHAn group (N = 18) with a normal proportion of DHA. Compared to DHAn, DHA- patients had a higher number of hospitalizations and a lower quality of life in terms of perceived health and physical health. They also exhibited significant higher interleukin-6 and cortisol blood levels. These results emphasize the importance of measuring membrane lipid and immunoinflammatory biomarkers in stabilized patients to identify a specific subgroup and optimize non-pharmacological interventions. It could also guide future research aimed at proposing specific pharmacological treatments.

Cognitive Impairment Mechanism in Patients with Bipolar Disorder.

Bipolar disorder (BD) is a common chronic mental disorder usually characterized by manic, hypomanic and depressive episodes. Patients diagnosed with BD have cognitive impairments in both the mood attack and remission stages, that is impairment of attention, memory and executive function. Up till the present moment, the causative mechanisms of cognitive impairment in BD patients remain poorly understood. Several studies have demonstrated that cognitive impairment in patients with bipolar disorder is not associated with a single factor, but with gene polymorphism, brain structural and functional variables, inflammatory and metabolic factors. Herein, we reviewed and summarized the recent reports on cognitive impairment mechanisms in patients with BD. To prevent or alleviate cognitive damage at an early stage, we propose that future research should focus on investigating the pathological mechanism of specific cognitive dimension damage as well as the pathological mechanism network between the damage of each dimension. It is crucial to recognize mechanisms of cognitive impairment for improving the symptoms and prognosis of BD patients, restoring their social function and integration.

A Prospective Observational Study on Assessment of Prescribing Pattern and Effectiveness of Psychotropic Medication on Schizophrenia in a Tertiary Care Hospital

Abstract: Aim: Schizophrenia is a chronic mental disorder that is related to poor physical health, early death and severe functional impairment. Schizophrenia is a worldwide condition that affects 1% of the population. It refers to a category of symptoms that involve disorganized and bizarre thinking, delusions, hallucinations, inappropriate affect and poor psychosocial functioning. Aim/Background: The main aim of the study is to assess the prescribing pattern and effectiveness of psychotropic medication on schizophrenia. Materials and Methods: Patient data was collected using data collection form which included the demographic details, mental status examination, diagnosis and medications. Assessment of prescription pattern was done by analyzing the prescription of 30 patients. Effectiveness was evaluated using PANSS SCALE. Results: A total of 30 patients with schizophrenia were studied. Anti-psychotics were prescribed to 27 (90%) of the patients. Anti-depressants were prescribed to 5 (16.7%) patients. Mood stabilizers were prescribed to 2 (6.7%) patients. Tranquilizers/hypnotics were prescribed to 8 (26.7%) patients. Anti- cholinergic were prescribed to 11 (36.7%) patients. Other psychiatry drugs were prescribed to 4 (13.3%) patients. There was a significant reduction in PANSS score before and after treatment. This shows that psychotropic medication are effective in treating patients with schizophrenia. Conclusion: The present study concludes that antipsychotics are the most prescribed drugs in schizophrenia followed by anticholinergic. Psychotropic medications are effective in treating schizophrenia as it was proved by PANSS score analysis. The study report also showed that the impact of drug therapy was more effective in males than in females as it shows a significant improvement in the symptoms of schizophrenia. Keywords: Effectiveness, Prescription pattern, Gender, Polypharmacy, PANSS and Schizophrenia.

Bipolar disorders in Nigeria: a mixed-methods study of patients, family caregivers, clinicians, and the community members’ perspectives

BackgroundBipolar Disorders (BDs) are chronic mental health disorders that often result in functional impairment and contribute significantly to the disability-adjusted life years (DALY). BDs are historically under-researched compared to other mental health disorders, especially in Sub-Saharan Africa and Nigeria.DesignWe adopted a mixed-methods design. Study 1 examined the public knowledge of BDs in relation to sociodemographic outcomes using quantitative data whilst Study 2 qualitatively assessed the lived experiences of patients with BDs, clinicians, and family caregivers.MethodsIn Study 1, a non-clinical sample of n = 575 participants responded to a compact questionnaire that examined their knowledge of BDs and how they relate to certain sociodemographic variables. One-way ANOVA was used to analyse quantitative data. Study 2 interviewed N = 15 participants (n = 5 patients with BDs; n = 7 clinicians; n = 3 family caregivers). These semi-structured interviews were audio-recorded, transcribed, and thematically analysed.ResultsIn Study 1, findings showed no statistically significant differences, suggesting low awareness of BDs, especially among vulnerable populations such as young people and older adults. However, there was a trajectory in increased knowledge of BDs among participants between the ages of 25–44 years and part-time workers compared to other ages and employment statuses. In Study 2, qualitative findings showed that BDs are perceived to be genetically and psycho-socially induced by specific lived experiences of patients and their family caregivers. Although psychotropic medications and psychotherapy are available treatment options in Nigeria, cultural and religious beliefs were significant barriers to treatment uptake.ConclusionsThis study provides insight into knowledge and beliefs about BDs, including the lived experiences of patients with BDs, their caregivers and clinicians in Nigeria. It highlights the need for further studies assessing Nigeria's feasibility and acceptability of culturally adapted psychosocial interventions for patients with BDs.

Promoting Psychosocial Health of Family Caregivers of Patients with Chronic Mental Disorders: A Review of Challenges and Strategies.

The present study aimed to investigate the mental and social health challenges of family caregivers of the patients with chronic mental disorders (CMD) and strategies which can be helpful in this regard. This study is a narrative review conducted in PubMed, Web of Science, Scopus, Elsevier, Google Scholar, Proquest, Magiran, and Sid databases where keywords such as Family caregiver, Chronic Mental disorder, Health Promotion, Program, Psychosocial, Support, Challenge, and Problem were searched in both Persian and English. A total of 5,745 published documents were found and were screened based on inclusion and exclusion criteria. Finally, 64 studies were found which had examined the related challenges, needs and strategies. According to the results, information deficits, needs for support, community participation deficits, and psychological suffering were recognized as challenges of family caregivers of these patients. Moreover, empowerments programs for the enhancement of the knowledge and skills of caregivers and peer-centered support programs were used to improve the level of mental and social health of family caregivers of these patients. Psychosocial problems and challenges that family caregivers of the patients with CMD face affect their health, satisfaction and quality of life. Using a collaborative approach, mental health service providers and government systems can help improve the psychosocial health of caregivers. The related managers and policymakers can reduce the emotional and psychological burden of families and promote their psychosocial health through developing a comprehensive program including practical objectives and strategies and taking into account the challenges that exist for caregivers in caring for patients with CMD.

The Effect of the Web-Based Psychosocial Health Promotion Program on the Burden of Care in Family Caregivers of Patients with Chronic Mental Disorders.

Family members of Chronic Mental Disorders (CMD), who are responsible for patient care, face many physical, psychological, and social problems which make them face the burden of care. This study aimed to investigate the effect of a psychosocial health promotion program on the care burden of family caregivers of patients with CMD. This is a quasi-experimental study that was conducted in two intervention and control groups in the form of pretest and posttest. This study was performed on 67 family caregivers of patients with CMD in Farabi and Noor centers in Isfahan, Iran. Participants in this study were randomly divided into two intervention and control groups. Data from the intervention and control groups were collected in two stages, before and after the intervention by demographic information form and Zarit burden questionnaire. The intervention group received a web-based psychosocial health promotion program in eight sessions in 4 weeks. At the end of the intervention, the Zarit questionnaire was completed by the intervention and control groups. The mean score of care burden between the intervention and control groups was not statistically significantly different before the implementation of the program (p = 0.534). But after the intervention, the mean score of care burden was significantly different between the two groups (t65 = 3.43, p = 0.001). This study provides evidence for the benefits of web-based psychosocial health promotion program in reducing the perceived care burden of the caregiver of CMD.

Hardware Psychodiagnosis of Resilience Indicators Mental Health

The article reveals the psychohygienic significance of apparatus-psychological objectification of the main indicators of mental health for each person to acquire knowledge about his own individuality and self-regulation of his own mental states. It is noted that self-control of one’s own mental functioning is necessary in the process of treatment of mental disorders and the long-term rehabilitation of patients with chronic mental illnesses, as it allows activating the awareness of the main objective parameters of one’s own mental capabilities in relation to the desired capabilities necessary for a full-fledged life. The functions of the “Hyst” device, manufactured by the Kyiv Telekom-pneumatik plant under the patent of Dr. Sergii Boltivets, are presented as a separate device and a program installed on a computer that processes the received psychodiagnostic data. In accordance with the psychodiagnostic purpose of each of the components of the apparatus complex, its use allows to conduct reactometry, labiliometry and tremormetry of the psychomotor praxis of thinking of children and adults, starting, as a rule, from the age of 5. The device provides the possibility of choosing both a single signal and a series of 10 responses with separate calculation of the reaction of the right and left hand and leg. This provides a psychodiagnostic assessment of interhemispheric interaction and the presence of asymmetry of interhemispheric functioning and its severity. The obtained data are important for identifying the consequences of unconscious but existing craniocerebral injuries and other dysfunctions of psychophysical development. The results of psychological examinations of 2,548 people, including children and adults aged 5 to 82 years, regardless of mental health status, including both self-actualized individuals with high quality indicators of mental health and individuals with chronic mental disorders and various degrees of mental retardation. This made it possible to generalize the main indicators of the instrumental and psychological objectification of the main indicators of the stability of mental health. It was established that the functional indicators of reactometry, labiliometry and tremometry are the basic characteristics of individuality, activity and the ability to self-regulate, which are the main indicators of the stability of a person’s mental health. It was noted that such universal forms and patterns of mental self-organization of a person, which, being transformed during human life, are not lost, have the greatest value.

Hopelessness and life satisfaction in patients with serious mental disorders: A cross-sectional study.

The main purpose of treatment and management in chronic mental disorders is to improve the quality of life (QOL). Hopelessness indicates a significant cognitive vulnerability that is associated with suicide risk. It is important for clinicians to have information about their patients' life satisfaction and spirituality. This study was conducted to determine hopelessness and life satisfaction in patients who received service from a community mental health center (CMHC). This cross-sectional study was conducted with patients diagnosed with psychosis (n=66) and bipolar disorder (n=24) according to Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) criteria, at a community mental health center serving in a hospital located in eastern Turkiye. Data was collected by a psychiatrist between January and May 2019 with face-to-face interviews, using a questionnaire, Beck Hopelessness Scale (BHS) and Satisfaction with Life Scale (SWLS). In the study, it was found that the mean BHS and SWLS scores of the patients did not differ significantly between the diagnosis groups (p>0.05). A moderately negative correlation was found between the patients' mean BHS and SWLS scores (rs=-0.450, p<0.001). In addition, it was determined that the hopelessness level of the secondary school graduates was low (p<0.05), the mean BHS score increased as the age and time from diagnosis of the patients increased (p<0.001), and there was a low negative correlation between the time from diagnosis and the mean SWLS score (rs: -0.208; p<0.05). In this study, it was found that the hopelessness level of the patients was low, their life satisfaction was moderate, and as the hopelessness level increased, their life satisfaction decreased. In addition, it was determined that the hopelessness and life satisfaction levels of the patients did not differ by to the diagnosis groups. It is extremely important for mental health professionals to consider aspects such as hope and life satisfaction, which are key in the recovery of patients.