Use Of Chlorhexidine Gluconate Research Articles

An in vivo study of dietary factors in the aetiology of tooth staining associated with the use of chlorhexidine

An in vivo study was carried out to investigate the role of tea, coffe and cigarette smoking upon the staining of teeth associated with the use of chlorhexidine gluconate. Three groups of volunteers, one of which consisted of cigarette smokers, rinsed with a 0.2% chlorhexidine gluconate mouthwash three times a day throughout two 10 day periods. The two non smoking groups were allocated tea and coffe respectively for consumptionduring on 10 day period. The smoking group were allocated coffee during one 10 day period. During the other 10 day periods the volunteers refrained from all hot beverages. A fourth group refrained from all hot bevrages during a 21 day period. The staining which developed on the previously cleaned teeth and tongues of the volnteers at the end of the respective rinsing periods was scored. All volunteers kept a diet record throughout the whole study. The drinking of tea and coffe significantly increased staining of teeth and tongue when compared with not drinking. Staining by tea was significantly worse than staining by coffee. Cigarette smoking appeard to have an additive effect on the staining. Dietary analysis indicated that other factors ar important to development of chlorhexidine staining and some apeared particularly chromogenic in this respect.

Use of Chlorhexidine Gluconate to Prevent Bone Resorption in the Rice Rat

Use of Chlorhexidine Gluconate to Prevent Bone Resorption in the Rice Rat

Use of chlorhexidine gluconate and povidone iodine mouthwashes in the treatment of acute ulcerative gingivitis

A trial was conducted to compare the effectiveness of povidone iodine and chlorhexidine gluconate with buffered peroxyborate in the treatment of acute ulcerative gingivitis. After 20 patients had entered the trial and 11 had required additional therapy with metronidazole to control their symptoms, the study was terminated. Those patients receiving peroxyborate all showed a satisfactory improvement in clinical signs and symptoms. One patient each receiving povidone iodine or chlorhexidine reported a symptomatic improvement, although gingival ulceration was still apparent at 1 week. The remaining patients all required metronidazole therapy to control their symptoms. Povidone iodine and chlorhexidine gluconate therefore cannot be recommended for the treatment of acute ulcerative gingivitis.