Bi-isotropic media (chiral and non-reciprocal) present an outstanding challenge for the scientific community. Their characteristics have facilitated the emergence of new and remarkable applications. In this paper, we focus on the novel effect of chirality, characterized through a newly proposed formalism, to highlight the nonlinear effect induced by the magnetization vector under the influence of a strong electric field. This research work is concerned with a new formulation of constitutive relations. We delve into the analysis and discussion of the family of solutions of the nonlinear Schrödinger equation, describing the pulse propagation in nonlinear bi-isotropic media, with a novel approach to constitutive equations. We apply the extended -expansion method with varying dispersion and nonlinearity to define certain families of solutions of the nonlinear Schrödinger equation in bi-isotropic (chiral and non-reciprocal) optical fibers. This clarification aids in understanding the propagation of light with two modes of propagation: a right circular polarized wave (RCP) and a left circular polarized wave (LCP), each having two different wave vectors in nonlinear bi-isotropic media. Various novel exact solutions of bi-isotropic optical solitons are reported in this study. Introduction: The investigation of exact solutions for nonlinear partial differential equations (PDEs) holds significant importance in understanding nonlinear physical phenomena. Nonlinear waves manifest across various scientific domains, notably in optical fibers and solid-state physics. In recent years, several potent methodologies have emerged for identifying solitons and periodic wave solutions of nonlinear PDEs. These include the -expansion method [1-6], the new mapping method [9-10], the method of generalized projective Riccati equations [11-16], and the expansion method [17]. Consequently, an original mathematical approach is proposed to evaluate nonlinear effects in bi-isotropic optical fibers, stemming from magnetization under the influence of a strong electric field [19-20]. The extended -expansion method emerges as a potent technique for deriving solution families of the nonlinear Schrödinger equation in bi-isotropic optical fibers. This method employs a perturbation expansion in powers of the dimensionless parameter and is applicable for both weak and strong nonlinearities. It accommodates varying dispersion and nonlinearity, rendering it suitable for modeling a wide array of optical fibers. Results and Conclusion: This investigate is concerned with a new formulation of constitutive relation linking to the magnetic effect, to understand rigorously the physical nature of biisotropic effects and to generalize the main macroscopic models. We inferred the nonlinear Schrodinger equation for a bi-isotropic medium term with a nonlinear term of magnetizing. In this article, the extended -expansion method is a powerful technique for determining a family of solutions of the nonlinear Schrödinger equation in bi-isotropic optical fibers. This method is based on the use of a perturbation expansion in powers of the dimensionless parameter, and it is valid for both weak and strong nonlinearities. The method allows for the inclusion of varying dispersion and nonlinearity, making it well-suited for modeling a wide range of optical fibres. Overall, the extended -expansion method is a valuable tool for understanding the dynamics of nonlinear optical systems, and it is expected to have a wide range of applications in the field of nonlinear optics.