Chimpanzee Chromosome Research Articles

Chromosome No. 1 of man and Chimpanzee: Identity of gene mapping for three loci: PPH, PGM1, and Pep-C

Cytogenetic and biochemical analysis of 10 independant Chimpanzee-Mouse cell hybrids and of 18 subclones of one of these showed that PPH, PGM1 and Pep-C are localized on the Chimpanzee chromosome homologous to the human chromosome No. 1.

Fluorescence of the trisomic chimpanzee chromosomes.

The chromosomes of a trisomie chimpanzee (Pan troglodytes) previously reported were reexamined with quinacrine fluorescence. The trisomie chimpanzee was found to have three small acrocentrics with intense fluorescence, analogous to the trisomy 21 that is responsible for Down’s syndrome in man. Comparison with the fluorescence of the parental chromosomes did not allow discrimination of the origin of the additional chromosome.

Is chromosome banding a really new tool to prove genetic homology between Man and apes?

In an attempt to make a critical interpretation of the results yielded by comparison between the chromosomes of Man and Chimpanzee treated with different denaturing agents for producing bands, the action of these substances is briefly discussed.

A comparison of the fluorescent karyotypes of the chimpanzee ( Pan troglodytes) and man

Individual chimpanzee chromosomes have been identified by their characteristic banding revealed by quinacrine fluorescent staining. A fluorescent karyotype of this species was set up to be compared with the standard human fluorescent karyotype. It was found that chromosomes 1, 3, 11, 12, 14 and X-chromosome of the chimpanzee appear to have banding patterns similar to the equivalent human chromosomes. Chromosomes 6, 7, 8, 10 and 13 also had a fluorescent pattern corresponding to the human chromosomes of the same number, particularly in the long arm. Remarkable variation in intensity and/or size of fluorescent regions was frequently found in the short arm of satellited acrocentric chromosomes 13, 14, 15, 22 and 23. Variations occurred between homologues and between individuals. Such variable fluorescence in a specific chromosomal region of an individual animal is a reproducible characteristic. Unlike its human counterpart, the distal segment in the long arm of the chimp's Y-chromosome is not brightly fluorescent. An earlier report is thus confirmed.

A comparison of chimpanzee and human chromosomes using the Giemsa-11 and other chromosome banding techniques.

Chimpanzee and human chromosomes have been compared after staining by Giemsa-11, trypsin banding, quinacrine fluorescence, and centromeric heterochromatin techniques. The Giemsa-11 technique appears to stain areas containing a particular DNA satellite fraction. All but three chimpanzee chromosomes could be assigned fairly definite homologs in the human karyotype. The most common form of rearrangement between chromosomes in the two species appears to be pericentric inversion.

Banding Pattern in Chromosomes of a Female Chimpanzee (<i>Pan troglodytes</i>)

Banding Pattern in Chromosomes of a Female Chimpanzee (<i>Pan troglodytes</i>)

The Chromosomes of the Chimpanzee

The Chromosomes of the Chimpanzee