Objective: Recognizing the seasonal and monthly variation of Guillain Barre syndrome. Design: Retrospective observational study. Setting: Pediatric wards and Pediatric Intensive Care Unit. Methodology: A medical record files of 52 patients of GBS, between the periods of May 2011 to April 2016 were recovered from Medical Record and Statistics Section of institute. Files were analyzed for demographic data, antecedent’s factors, time of occurrence with respect to months & seasons and data was analyzed. Result: In our series females are outnumbered to male and most of the cases in age group 6-12years, 46.15% were belongs to lower socioeconomic status. In 51.92% cases, antecedents were present at the beginning of clinical picture and upper respiratory tract infection (26.84%) & diarrohea (18.23%) were noted. The highest incidences of Guillain Barre Syndrome 48.08% cases were seen in monsoon, 21.15% in summer, 13.46% in post monsoon and 17.31% in winter season. Though the syndrome occurred sporadically throughout the year, the month wise peak was highest in month June followed by July. Conclusion: Seasonal and monthly variation of childhood Guillain Barre syndrome differs from adult GBS and it is most commonly in monsoon season.Objective: Recognizing the seasonal and monthly variation of Guillain Barre syndrome. Design: Retrospective observational study. Setting: Pediatric wards and Pediatric Intensive Care Unit. Methodology: A medical record files of 52 patients of GBS, between the periods of May 2011 to April 2016 were recovered from Medical Record and Statistics Section of institute. Files were analyzed for demographic data, antecedent’s factors, time of occurrence with respect to months & seasons and data was analyzed. Result: In our series females are outnumbered to male and most of the cases in age group 6-12years, 46.15% were belongs to lower socioeconomic status. In 51.92% cases, antecedents were present at the beginning of clinical picture and upper respiratory tract infection (26.84%) & diarrohea (18.23%) were noted. The highest incidences of Guillain Barre Syndrome 48.08% cases were seen in monsoon, 21.15% in summer, 13.46% in post monsoon and 17.31% in winter season. Though the syndrome occurred sporadically throughout the year, the month wise peak was highest in month June followed by July. Conclusion: Seasonal and monthly variation of childhood Guillain Barre syndrome differs from adult GBS and it is most commonly in monsoon season.