AIMS: To study the peculiarities of epidemiology, etiology and clinical course of allergic diseases in different regions of the Russian Federation. MATERIALS AND METHODS: To achieve this goal, a questionnaire survey of chief specialists was conducted in 2019. Questionnaires were sent to all regional, republican centers and cities of federal significance. The received data were analyzed and structured. RESULTS: Responses to the questionnaires were received from 49 regions of the Russian Federation, where a total of 1468105 patients with allergic diseases were registered during the study period. Significant discrepancies in the structure of allergic diseases and the spectrum of etiologically significant allergens were revealed in different regions of the Russian Federation, reflecting their climatogeographical peculiarities. There is an increase in respiratory forms of allergy, multysensitization and multi-organ allergic lesions. Low availability of specialized care and insufficient prescription of pathogenetic allergen-specific immunotherapy (ASIT) were found in all federal districts of the Russian Federation. CONCLUSIONS: Different climatogeographic regions of the Russian Federation differ from each other in the structure of allergic diseases and sensitization spectrum, which should be taken into account in the development of preventive, diagnostic and therapeutic measures in these territories.
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