Chief Doctor Research Articles

Mykola Motsakov — in the field of the Red Cross

The article represents a life and a professional path of zemstvo doctor Mykola Petrovych Motsakov. His contribution to the development of the medical service in Katerynoslav has been presented: he worked in the community of mourning sisters, was the first chief doctor in the field of the Red Cross. He died prematurely in the prime of his life in the line of duty. Excerpts from the diary of Princess Vera Urusova about his mother have been provided. The presented material will contribute to the popularization of the figure of the Ukrainian zemstvo doctor.

Knowledge collaboration and online medical teams’ performance: a multiple participation perspective

PurposeOnline medical teams (OMTs) have emerged as an innovative healthcare service mode that relies on the collaboration of doctors to produce comprehensive medical recommendations. This study delves into the relationship between knowledge collaboration and team performance in OMTs and examines the complex effects of participation patterns.Design/methodology/approachThe analysis uses a dataset that consists of 2,180 OMTs involving 8,689 doctors. Ordinary least squares regression with robust standard error is adopted for data analysis.FindingsOur findings demonstrate a positive influence of knowledge collaboration on OMT performance. Leader participation weakens the relationship between knowledge collaboration and team performance, whereas multidisciplinary participation strengthens it. Passive participation and chief doctor participation have no significant effect on the association between knowledge collaboration and OMT performance.Originality/valueThis study provides valuable insights into how knowledge collaboration shapes OMTs' performance and reveals how the participation of different types of members affects outcomes. Our findings offer important practical implications for the optimization of online health platforms and for enhancing the effectiveness of collaborative healthcare delivery.

Professional and social role of the chief doctor of the clinic

Competition in the healthcare market leads to quality of medical services, optimization of medical service costs and retention of medical personnel. Optimizing patient service design in a clinic refers to the entire process of treatment from patient admission to discharge. Successful strategic and operational management is ensured by positioning leadership in a unified process. The chief physician must recognize that, in addition to providing personal services, his task is to continuously optimize processes in terms of medical quality, service quality, and cost effectiveness. Medical quality, service quality and economic efficiency should be coordinated and optimized.

Continuity of Ideas and Generations. Historical Facts About the Activities of the Sheremetev Hospital (for the 100th Anniversary of the N.V. Sklifosovsky Research Institute for Emergency Medicine)

BACKGROUND The activities of the Hospice House established by Count N.P. Sheremetev and opened on June 28, 1810, pursued a noble goal to help the suffering, sick and low-income people. However, this intention alone was not enough, and N.P. Sheremetev took care to really ensure the stable work of the Hospice House, providing for both its publicity and reliable state protection.MATERIAL AND RESEARCH METHODS Annual financial statements of the Hospice Board of Trustees for 1862–1866, 1868, 1871, 1872 and 1902 were introduced into scientific circulation for the first time. To prepare the article, archival material was used, including 6 sources, as well as rare publications dated 1859–1927. Research methods: historical-genetic, comparative-historical, problem-chronological and systemic.RESULTS The analysis of the activities of the Sheremetev hospital for 1810–1909 showed that funds were enlarged regularly with increasing amounts from its budget for the treatment of patients, which number was maximum in 1865 (1,798 people), and the lowest in 1814 (127 people).The personnel of the Sheremetev Hospital took an active part in all major military operations with the participation of Russia (the creation of sanitary detachments to provide assistance to the wounded and sick in combat areas, as well as additional beds located on the territory of the hospital itself).The Sheremetev Hospital played an important role in higher medical education in Russia, becoming the clinical base of the Moscow Medical and Surgical Academy, and later of the Faculty of Medicine of Moscow University; many of its employees were teachers of these educational institutions. The high level of teaching was also ensured by equipping the hospital with modern medical devices and the active introduction of the latest medical achievements into its work.On the initiative of chief doctor A.T. Tarasenkov, a department for incoming patients was organized as an independent structure for the first time in Russia. It provided assistance to 175–200 patients per day. The department became the prototype of a comprehensive outpatient network that was subsequently created in our country.The high prestige of the hospital was brought by the activities of its main doctors and operators, tirelessly working to improve the organizational and medical aspects of the provision of qualified medical care.The final period of the hospital’s activity (1910–1923) until the October Revolution was characterized by the greatest volume of medical work, which subsequently decreased dramatically due to financial difficulties. Since 1919, the hospital functioned as a state institution, and also became the base for the revival of the ambulance service in Moscow.CONCLUSION A review of the activities of the Sheremetev Hospital indicates that the organization of emergency medical care for the population of Moscow, pedagogic work, participation in the treatment of the wounded patients, high surgical activity and versatility were the foundation on which its work was widely developed. It is no coincidence that this particular hospital was reorganized in 1923 into the N.V. Sklifosovsky Institute of Acute Care (since 1944 — N.V. Sklifosovsky Research Institute for Emergency Medicine).Economic difficulties and political storms could not destroy what was created at the Sheremetev hospital and was the moral and material basis for the further 100 years of successful activity of the institute.

Visual Cascaded-Progressive Convolutional Neural Network (C-PCNN) for Diagnosis of Meniscus Injury.

The objective of this study is to develop a novel automatic convolutional neural network (CNN) that aids in the diagnosis of meniscus injury, while enabling the visualization of lesion characteristics. This will improve the accuracy and reduce diagnosis times. We presented a cascaded-progressive convolutional neural network (C-PCNN) method for diagnosing meniscus injuries using magnetic resonance imaging (MRI). A total of 1396 images collected in the hospital were used for training and testing. The method used for training and testing was 5-fold cross validation. Using intraoperative arthroscopic diagnosis and MRI diagnosis as criteria, the C-PCNN was evaluated based on accuracy, sensitivity, specificity, receiver operating characteristic (ROC), and evaluation performance. At the same time, the diagnostic accuracy of doctors with the assistance of cascade- progressive convolutional neural networks was evaluated. The diagnostic accuracy of a C-PCNN assistant with an attending doctor and chief doctor was compared to evaluate the clinical significance. C-PCNN showed 85.6% accuracy in diagnosing and identifying anterior horn injury, and 92% accuracy in diagnosing and identifying posterior horn injury. The average accuracy of C-PCNN was 89.8%, AUC = 0.86. The diagnosis accuracy of the attending physician with the aid of the C-PCNN was comparable to that of the chief physician. The C-PCNN-based MRI technique for diagnosing knee meniscus injuries has significant practical value in clinical practice. With a high rate of accuracy, clinical auxiliary physicians can increase the speed and accuracy of diagnosis and decrease the number of incorrect diagnoses.

Laveran, the Pasteurian researcher

At the end of his professorial mandate at the Val de Grâce hospital, Alphonse Laveran, who was Chief Doctor, was appointed to Lille and then Nantes. These assignments however deprived him of a hospital service where he could carry on his research. In 1896, faced with the inflexibility of his military hierarchy, he applied for early retirement; he was then 50 years old. Dr Roux welcomed him to the Pasteur Institute as a honorary department head, where he started a second career as a volunteer. He would spend the following 25 years there, addressing the great protozoology issues. Together with Félix Mesnil, he undertook the study of trypanosomiasis and leishmaniases. In 1907 he was awarded the Nobel Prize in physiology and medicine to honor "his work on the role of protozoa as pandemic vectors". He allocated a large part of his prize money to set up a parasitology laboratory at the Pasteur Institute, where all the discoveries and observations carried out in the colonies would converge. In 1908, he funded the Society of Exotic Pathology. He authored no less than 600 publications where his memorable research is recorded. Despite his somewhat outwardly rigid appearance, the man proved to be of amiable approach thanks to "the simplicity of his manners, his amenity and his great heart".

Перспективні напрямки розробки засобів, що здатні підвищувати адаптаційні можливості організму людини в умовах негативного впливу середовища життєдіяльності

Abstract. The ever-increasing anthropogenic chemical load throughout the world prompts the search for sources of biologically active substances (BAS) capable of increasing the adaptive capabilities of a person exposed to the harmful effects of the environment. Aim. Scientific substantiation of the optimal composition of recipes and features of the production technology of products with immunomodulating and adaptogenic effects (dietary supplements, detoxification products for external use, including cosmetic preventive products for hand skin disinfection), based on technologically processed vegetable waste used in the production of pharmaceutical products Proteflazidum®". Material and Methods. The chemical composition of the ethanol extract of the plant raw material "Proteflazidum®" and the waste of its production - meal was studied. The mass fraction of flavonoid compounds aglycones of tricin, apigenin, luteolin, amino acids, sugars, carboxylic acids, natural polymers (pectin substances, chlorophylls and hemicellulose), ethanol (%, vol) was determined. The methods of ultra-high-performance high-speed liquid chromatography with diode-matrix detection (UPLCPDA, Waters, USA) were used; method of ultra-high-performance mass spectrometric high-speed liquid chromatography with electron spray ionization (UPLC-MC/MC, Waters, USA). A study of the dietary supplements "Immunoflazid Light" (syrup) and "Immunoflazid Pro" (capsules), manufactured in accordance with TU U 10.8-25589583-001:2020, was conducted according to safety indicators: the content of heavy metals, pesticides and radionuclides for compliance with the requirements of GN 4.4.8.073 -2001 "Temporary hygienic standards for the content of chemical and biological contaminants in biologically active supplements", approved by the resolution of the chief state sanitary doctor of Ukraine dated 04.20.2001. No. 131 and GN 6.6.1.1-130-2006 "Permissible levels of the content of radionuclides 137Cs, 90Sr in food and drinking water", approved by the order of the Ministry of Health of Ukraine dated 05.03.2006 under No. 256. A spectrometer was used to determine the content of lead, cadmium, and mercury atomic emission "SHIMADSU ICPE - 9820"; for the determination of radionuclides, the spectrometer "SEG-001", "AKP-S" and the spectrometer "SEB-01-70" were used. Methods of measuring pesticides according to DSTU EN 12393-1:2003, DSTU EN 12393-2:2003, DSTU EN 12393-3:2003 and GOST 30349-96. Results. The waste of vegetable raw materials, which is formed as a result of the production of the "Proteflazidum®", is a valuable source of BAS, which allows you to consider them as raw materials for creating recipes of products with an adaptogenic effect - dietary supplements and raw materials for the production of products for external use, including cosmetic prophylactic and means for hand skin disinfection. According to safety indicators, the new products belong to low-hazard substances when applied to the skin (hazard class 4), do not show skin-irritating, skin-resorptive and sensitizing properties, alcohol-free products do not irritate the mucous membrane of the eyes. Conclusions. Proteflazidum® production waste is a valuable raw material for the creation of a wide range of products with an adaptogenic effect (dietary supplements, raw materials for the production of products for external use, including cosmetic prophylactics and products for hand skin disinfection). Key Words: Proteflazidum®, Herba Deschampsia Сaespitosa L., Herba Calamagrostis Epigeios L., bioflavonoids, pectin substances.

Knowledge level of cardio-oncology in oncologist and cardiologist: a survey in China.

Knowledge level of cardio-oncology in oncologist and cardiologist: a survey in China.

Propositional Inference for IoT Based Dosage Calibration System Using Private Patient-Specific Prescription against Fatal Dosages.

IoT-based insulin pumps are used to deliver precise quantities of insulin to diabetic patients to regulate blood glucose levels. Generally, these levels correspond to the dietary patterns observed at time intervals that vary between patients. However, any misrepresentation in insulin levels may lead to fatal consequences. As a result, most IoT-based insulin pumps are rejected due to the possibility of external threats, which include software and hardware attacks. However, IoT-based insulin pumps are extremely useful in real-time patient monitoring, and for controlled insulin delivery to the patient based on their current glucose level. We propose a blockchain-based method to protect against the above-mentioned attacks. The system creates a patient-specific private blockchain wherein the dosage information is added as a new block by obtaining the approval of the doctor, chief doctor, nurse, and caretaker of the patient who are authorized blockchain miners. Secondly, it securely transfers prescription data, such as dosage quantity and time of delivery, to the IoT insulin pump, which ensures the dosage information is not modified during transit before insulin administration to the patient. The proposed approach uses a state-behavior-based solution that detects anomalies in the behavior of the insulin pump via temporal data analysis and immutable ledger verification, which are designed to eliminate fatal dosages in case of anomalies. The system is designed to work within binary outcome conditions, i.e., it verifies and delivers dosage or halts. There is no middle ground that an attacker can exploit, resulting in accountability for the system.

Two Villiers

The article presents biographical data and the contribution to military medicine of Life Doctors Yakov Vasilyevich Willie 1st (President of the Medical and Surgical Academy) and Yakov Vasilyevich Willie 2nd (Chief Doctor of Military Educational Institutions).

Топография Симонаса Даукантаса в Санкт-Петербурге

Simonas Daukantas’s Topography of St Petersburg S u m m a r y Simonas Daukantas spent 15 years (between 1834 and 1850) living in St Petersburg, where he worked as an assistant registrar at the Senate. This article highlights the exact addresses of where Daukantas lived and published books in St Petersburg. The address of the place where Daukantas lived in 1837 is published for the first time; the drawing of the building has been obtained, the landlord identified. Apparently, in 1837 Daukantas lived in the building owned by Marya Nelsen, the wife of chief (regiment) doctor Gavrila Nelsen, at the intersection of Kazanskaya street and Voznesensky prospect (or Voznesensky avenue; the exact address: Voznesensky Ave 15–17/Kazanskaya St 45). The article features the drawing of this building and contains information about its condition, which shows that in late 1830s and in 1840s the building was in an appalling state of repair. Marya Nelsen died in 1840, and the building was assigned to a care agency. Some of the tenants continued to live at the building for some time, only to move out later; apparently, Daukantas was among those who vacated this residence. More details are provided about Daukantas’s place of residence in 1842 (address: Malaya Masterskaya 9, the building near the Church of St Stanislaus), providing the drawing of the building and publishing pictures of how it looks today, revealing the characteristics of the building’s architecture, including those from the time when Daukantas lived there. The building next to St Stanislaus Church at Malaya Masterskaya 9 was built in 1841–1842. In one letter of 1842 Daukantas claimed his residency at this address, so we suggest that he might have moved in right after the completion of construction. The addresses of three printing houses where Daukantas published his books have been identified. On top of that, details of what the buildings looked like during Daukantas’s time there have been obtained. Christian Hintze’s printing house was located at Durygina’s house at Nevsky prospect 8. The building has survived to this date virtually intact. Ivanov’s lithograph based on Sadovnikov’s picture represents the view of the building in 1830s, the approximate time of Daukantas’s book publications at Hintze’s printing house. Later, the enterprise was acquired by Merkushev. The printing house of Karl Kray was located in the corner of Frost’s building at Malaya Morskaya 12/Gorokhovaya 9. Analysis of the archive drawings of the buildings has provided some insights into what the building’s appearance was during Daukantas’s time in St Petersburg. Before 1850, Gretsch’s house (current address: Moika 92; the building was demolished in early 1960s) was home to Eduard Pratz’s printing house. The blueprints of the building that were found in the archives shed a light on what the building looked like in 1840s and 1850s, when Daukantas would publish his books there. Gretsch’s own publishing house was in the same building. The archives contain blueprints of Gretsch’s house on Moika riverfront, showing the appearance of the building at the time of Daukantas’s printing his books there: the façade off Moika, the courtyard, and the plan of the building. Giedrius Subačius has noted that 1841–1845 were the years when Daukantas was the most consistent in his orthography. Βetter living conditions in the new building constructed in 1842 most probably had allowed Daukantas to improve the quality and efficiency of his work. It is also worth noting that the publishing houses were close to the places where Daukantas lived and worked. All these buildings are located in the Admiralteisky district of St Petersburg.

The contribution of the Scottish doctor Robert Erskine to the development of Russian medicine in the 18th century.

The Scottish doctor Robert Erskine (1677-1718) became Chief Doctor of Russia and personal physician to Tsar Peter the Great. Extensive archival material documents his remarkable career. From schooling in the village of Alva and apprenticeship to an Edinburgh apothecary, he went on to study medicine in Paris and Utrecht and was admitted to the Royal Society in London. Recruited into the service of the Tsar, to whom he became a trusted friend and counsellor, Erskine played a central role in the modernisation of Russian medicine, pharmacy and natural science in the early 18th century. His untimely death at age 41 was marked with a state funeral in St Petersburg. Some historians in Russia assert that in their country, the development of medicine and the natural sciences took place without the transitional stages of iatrochemistry and iatrophysics which characterised the shift in scientific thinking throughout Europe in the early modern period. This study of archival records shows that Erskine held iatrophysical and iatrochemical views in common with his European contemporaries. His influence ensured that Russia was thoroughly involved in European developments in science and medicine in the 18th century.

Московский госпиталь в первой половине XVIII века: начало славного пути

The article highlights the formation of the Moscow Hospital, founded by the Decree of Peter I in 1706 in Lefortovo, and its activities in the first half of the XVIII century as a clinical institution, where from the first days the treatment of patients took place together with the training of the first Russian doctors – students of the Moscow Medical and Surgical School. The article tells about the first chief doctor and director of the Hospital School — Nikolai Bidloo — the author of the national “Instructio de chirurgia in theatro anatomico”, and his followers who devoted their lives to preserving the health of the Russian army.

Satisfaction of the rural population with the quality of medical care

The aim of the study. To evaluate satisfaction with the quality of medical care at the outpatient and inpatient stages on the example of the rural population of the Saratov region. Material and methods. The study involved 102 respondents (34 people from each municipal district) of both sexes aged 20 to 70 years, the average age was 46.3 [22.1; 68.3]. The study was conducted using a voluntary patient questionnaire. Results. Respondents are more satisfied with the medical care provided by round-the-clock hospitals and emergency medical teams in 47.1% and 43.1% of cases, respectively, and the least confident with polyclinics (on average, 35.2%). Half of the respondents attribute the decline in the quality of medical care at the outpatient and inpatient stages simultaneously to several factors (long waiting for a specialist consultation, lack of necessary medical equipment, the inattentive attitude of medical personnel to patients). The respondents react to the decrease in the quality of medical care in the following way: 9 (8.8%) of respondents wrote complaints about the medical worker to the chief doctor, 57 (55.9%) - expressed their dissatisfaction with the medical staff, trying to solve the problem at the initial stages of its appearance, 36 (35.3%) - did not show active actions. Discussion. The low level of satisfaction of rural population with quality of medical care, primarily due to understaffing of medical personnel and inadequate funding of health institutions, lack of high-level professional experience young professionals, the subjective perception of patients respondents on how to provide medical assistance based on information obtained from Internet resources. Conclusions. On average, 41.8% of patients are satisfied with the quality of medical care in the Saratov region. Recommendations offered for solving problems that cause a decrease in the quality of medical care in this area.

The state of carbohydrate metabolism in children with gallstone disease

Cholelithiasis (cholelithiasis) has become increasingly common in childhood. Currently, the features of the clinical course have been studied, the criteria for the diagnosis and prevention of cholelithiasis in children have been worked out. However, the features of metabolic disorders are still not studied, among which not the least role in the genesis of the formation of gallstones is played not only by the exchange of lipids, but also carbohydrates.The main role in the regulation of carbohydrate metabolism is played by insulin. The process of production of insulin in the body in the blood serum fully reflects the concentration of C-peptide. The ratio between insulin and C-peptide is not always constant. It may shift in one direction or another against the background of diseases of the internal organs, including the GI tract.The analysis for C-peptide and insulin allows you to identify not only hypo — or hyperglycemia, but also to determine insulin resistance, calculate the HOMA index and, accordingly, make a forecast for the development of dyslipidemia. In this regard, it was of interest to study the state of carbohydrate metabolism (glucose, insulin, C-peptide) in children with cholelithiasis.The purpose of the study. To improve the early diagnosis of the complicated course of cholelithiasis by studying the features of carbohydrate metabolism for practicing therapeutic tactics and preventive measures.Materials and methods. Under our supervision at the Department of Pediatrics infectious diseases, faculty of postgraduate education of physicians of the Russian national research medical University of Minzdrav of Russia (head.DEP. — M. D., Professor L. A. Kharitonov), city children’s polyclinic № 122 (chief doctor — PhD Bragin A. I.) were 140 children aged from birth to 15 years. Carbohydrate metabolism was studied in 140 children of the study group. Boys were 62, average age 10.0±4.9, girls were 78, average age 8.8±4.5. The parameters of serum glucose, insulin, and C-peptide were evaluated. The Homeostatic Model Assessment (NOMA) Insulin resistance Index will be calculated using the formula: NOMA-IR = (fasting plasma glucose (mmol/l) x fasting serum insulin (mkED / ml))/22.5 (Cuartero B., 2007). The physical development of children was evaluated according to WHO standards (2006) using the WHO Anthro Plus program (2009). We evaluated the values of the average values of body weight(MT), height (body length, DT) and body mass index (BMI) in five groups of newborns. The nutritional status was determined by the values of the Z-score value. Mathematical calculation of the results was carried out on a personal IBM — compatible computer using the statistical program Statistica 6.0.Results. In children with GI, there was a tendency to increase the NOME index, both in frequency and in absolute terms, from the age of 8 and persisted until the age of 15(0,65±0,14;0,42±0,04; 4,89±1,12; 4,86±0,44; according to the age periods, p< 0.005).Conclusion. Thus, disorders of carbohydrate metabolism in children with GI depend on the child’s age and body weight. In overweight children, an increase in C-peptide, insulin, and the resistance index was observed, which suggests that children with GI occurring against the background of overweight at the age of 8–11 and 12–15 years are threatened by the formation of metabolic syndrome, diabetes mellitus, and arterial hypertension.

Expert Method as a Quality Assessment Tool of a Multifunctional Hospital

The systematic structural transformation of the system and the introduction of new technologies are not enough to create an effective system for the medical quality control. It is supposed, that the health care quality management system will be phased, so, it is necessary to emphasize the change in management decisions of medical care quality. The purpose of the research is to alter the traditional scheme of medical expertise conceptualization into innovation, which is based on effective motivation of staff. The object of the study was Astghik Medical Center, which is a multi-functional medical center. Combining medical errors with different components of medical care quality, determines the degree of their significance, which allows dividing medical error into 4 classes. Taking into account the severity of the medical error, the degree of discrepancy is divided into 6 classes. We have developed a Medical Record Examination Questionnaire: 340 medical records have been examined. The research results show, that, the second class of health care quality discrepancy is most common. As a result of analyzing, the following errors were discovered: Gather information about the patient (25.5%), drug therapy -the absence of the prescribed medication, the improper use of the medication (0.8%), error in treatment continuity (10.8%). The received data indicate that it is necessary to develop and introduce managerial decisions that will result in a reduction of medical care discrepancy error. In order to achieve this goal it is necessary to set up a working group, whose staff is desirable to involve the chiefs of departments and the assistant of chief doctor. Thus, managing of medical care quality within the limits of a separate medical institution confirms, that medical care quality can be improved by correctly using information about quality, by purposeful activity of the head, which will be aimed at solving main problem of medical care quality.

N.L. Bidloo, director of the Moscow hospital school. to the 310<sup>th</sup> anniversary of the first russian textbook of surgery (military field surgery)

The article presents data on the first handwritten textbook on surgery (military field surgery) for training military doctors in the Russian Empire in the early 18th century at the Moscow Hospital (Moscow Medical and Surgical) School. The author of the textbook was the Chief Doctor of the Moscow Hospital and the Director of the School Nicholas Bidloo. The textbook consists of 4 parts (129 chapters and 8 signs) in the main areas of medicine. The article provides a summary of Leib-medic Peter I Nicholas Bidloo.

Увольнение от службы (Отставка М. А. Достоевского по архивным документам 1837 года)

The least amount of documentary evidence has been preserved about the early period of F. M. Dostoevsky's life. Three documents discovered in the Russian state historical archive related to the 1837 resignation of Mikhail Andreevich Dostoevsky, the writer's father, are published and examined in the article. These are the report of the Moscow Board of Trustees to Nicholas I, the report of the chief doctor of the Mariinsky hospital for the poor A. A. Richter and the service record of M. A. Dostoevsky. The last document that provides important information about the official career of the writer's father, is provided in full for the first time in the Appendix to the article. The authors of preceding publications about the childhood and youth of F. M. Dostoevsky only referenced the service record of M. A. Dostoevsky or quoted the previously published passages. These documents contain the information about the size of the pension due to retired physician Dostoevsky, his service characteristics, and a list of his awards. The article raises one of the most debated questions, namely, the date of birth of the writer's father. Together, the documents on the resignation of M. A. Dostoevsky reveal new facts and clarify those already known from his 1830s biography, and therefore elucidate the circumstances of the great Russian writer's youth.

Utiliser les psychédéliques pour « guérir » des adolescents homosexuels ? Essai de thérapie de conversion, France, 1960

Between 1960 and 1962, a children's judge placed two French adolescents in a psychiatric hospital in Alsace. Described as “delinquent sexual perverts”, Michel, 15, and Bernard, 18, were in fact two young homosexuals. However, at the time, homosexuality was considered a psychiatric disorder that should be “cured”. With this in mind, psychiatrists set up shock or disgust therapies to push patients to become heterosexual. In this hospital, the chief doctor tested two new substances on them: mescaline and LSD. Injected in very high doses, the idea was to cause a powerful psychological shock in the hope of changing the adolescents’ sexual orientation. This type of placement as well as the treatment inflicted were then common (lobotomies or electroshocks were part of the “therapeutic” possibilities to “cure” homosexuality). Two aspects of these experiments are however particularly original: on the one hand, the use of substances such as mescaline and LSD, on the other hand, the very type of “therapy” implemented. It would thus seem, in the current state of knowledge on the use of LSD and mescaline in psychiatric therapy, that these experiences were isolated facts: the literature remains silent on the subject of the use of mescaline to “cure” homosexuality, and the few known therapies carried out using LSD were offered to adults and above all volunteers. Finally, these therapeutic methods were the opposite: psychotherapies in which particular attention was paid to patients and their well-being in the United States or in England and “psychic shocks” in Alsace. This hospital is the only French example of an attempt to “treat” homosexuality using psychedelics. The use of these substances by the French team therefore began in 1960; it involved administering mescaline or LSD in high doses (an exceptional characteristic in Europe where psychiatrists were in favor of therapy with low doses known as “psycholytic”) and in injections, ranging from 200 to 1200mg for mescaline and for LSD from 100 to 800micrograms. By way of comparison, a recreational dose is 300 to 500mg for mescaline and 100micrograms for LSD, administered orally. In order to create “psychic shock”, the effects of the substances were immediately stopped by the injection of chlorpromazine, a powerful neuroleptic. The authors noted that for all patients, “two modes of behavior are common: stupor and agitation”. They sometimes tore their sheets or pajamas or grabbed the examiner, asking for support. The sessions were linked: in 118 days, Bernard would undergo 16 of these sessions, one every 7 days on average. Michel, during one of the sessions, felt like he had been killed by his psychiatrists. Neither would subsequently become heterosexual. Elsewhere in the world, other forms of LSD conversion therapy have emerged. However, these were benevolent psychotherapies; the product was not injected but taken orally (therefore with more progressive effects), and the approach was not the same. Thus, acceptance of their homosexuality by patients was considered as desirable an option for therapists as was conversion to heterosexuality. For French practitioners, on the contrary, “healing” was the only objective. This article will highlight a double French specificity in the use of psychedelics: first, the refusal to introduce the new method of administering these substances, called “set and setting”, theorized from the late 1950s in Anglo-Saxon countries, and yet known and discussed by French experimenters. Then, it will show the use of these substances in shock therapy, particularly in the treatment of homosexuality.

Development of an integrated method for implementation of food diets to medical and health institutions

The object of research is the consumer preferences of visitors, the requirements of specialists in the field of science, production and catering. Existing diets, according to which visitors eat in sanatoriums and dispensaries, require immediate correction. A promising way is the development of specialized food culinary dishes and rations from them, which are successfully integrated and used, based on the mutual experience of specialists in the field of science, manufacturing enterprises and catering. This approach to solving the problem is the most effective and economically feasible, as evidenced by the accumulated experience and achievements of modern nutritional science. In the course of the study, the synectic method is used, based on the work of specialists in the field of science, production and catering. 4 working groups of 10–15 people each are formed. Scientists are employees of Kharkiv State University of Food Technology and Trade, V.N. Karazin Kharkiv National University, Lviv Polytechnic National University and V. Chornovol Sustainable Development Institute in Lviv (Ukraine). Food organizers: director, chief physician, nutritionist, chef of the Borisfen sanatorium (city of Berdsansk, Ukraine); chief doctor, nutritionist, head of the canteen of the Institute of Neurosurgery named after academician A.P. Romodanov of the National Academy of Medical Sciences of Ukraine (Kyiv, Ukraine); heads of the public organization «Lviv Regional Organization of the All-Ukrainian Ecological League» (Lviv, Ukraine); consumers – visitors to health facilities using the services 1–2 times a year.Within the framework of the study, an integrated implementation method is proposed, which will contribute to increasing the efficiency of using scientific developments. This will create a mechanism for the interaction of scientists with production and participants in the catering process with the end user. Due to this, solutions to the problem of national importance will be provided, which is associated with unbalanced diets.