A coordinated operation of smart grid (SG) and intelligent transportation system (ITS) provides electric vehicle (EV) owners with a myriad of power and transportation network data for EV charging navigation. However, the optimal charging navigation would be a challenging task owing to the randomness of traffic conditions, charging prices and waiting time at EV charging station (EVCS). In this paper, we propose a deep reinforcement learning (DRL)-based EV charging navigation, aiming at minimizing the total travel time and the charging cost at EVCS. First, we utilize the deterministic shortest charging route model (DSCRM) to extract feature states out of collected stochastic data and then formulate EV charging navigation as a Markov Decision Process (MDP) with an unknown transition probability. The proposed DRL-based approach will approximate the solution, which can adaptively learn the optimal strategy without any prior knowledge of uncertainties. Case studies are carried out within a practical zone in Xi’an city, China. Numerous experimental results verity the effectiveness of the proposed approach and illustrate its adaptation to EV driver preferences. The coordination effect of SG and ITS on reducing the waiting time and the charging cost in EV charging navigations is also analyzed.