Generalized inversion of the S-wave amplitude spectra from the strong-motion network data in the Alborz, Iran has been used to estimate simultaneously source parameters, site response and S-wave attenuation (Qs). To obtain an optimum inverse solution, and also for decreasing the uncertainty level, a frequency-dependent site amplification as a constraint, was imposed to five reference site responses. This constraint removes the undetermined degree of freedom in the inversion. Furthermore, for removing the trade-off between geometrical spreading and anelastic attenuation, a geometrical spreading factor was adopted from the Motazedian [20] study. A point source model has been calibrated against the resulting source terms and consequently source parameters, like corner frequency, moment magnitude and high frequency fall off coefficient, for each event has been determined separately. Also, based on the available data and their connectivity two sub-regions including western and eastern parts of Alborz located east and west of 52.5°E have been considered to see that if there is any possible systematic difference in their seismic source characteristics. The average stress drops obtained are about 182 and 116bars, respectively for eastern and western Alborz. Another result of the study is the site responses, which have been determined for all of 81 stations individually. Though soil nonlinearity was detected at the Ab-bar station (experienced strong ground shaking, i.e., PGA>0.5g) near to the epicenter of Manjil M7.4 earthquake of June 20, 1990, but an analysis of residuals showed generally a weak influence of soil nonlinearity (i.e., dependence of amplification on shaking level); probably because of the relatively weak levels of acceleration in our database. Finally, the shear wave quality factor (i.e., Qs) has been determined as a function of frequency represented by a linear equation in logarithmic scale. To evaluate the outcomes of the current study, the results have been compared with similar studies wherever it was available. The results of the current study are of utmost importance for seismic hazard assessment of the metropolitan area of Tehran, where 15 million people live, one-fifth of the population of Iran.