This paper presents an evaluation of two simulations by regional climate model (RCM) ALADIN-Climate/CZ with different sizes of integration domain and their driving simulation of global climate model (GCM) ARPEGE-Climat over central Europe during the period 1961–2010. After a brief evaluation of seasonal means of air temperature characteristics (daily mean, maximum and minimum temperature) and their variability, we focus on the ability of the simulations to represent observed changes in seasonal mean air temperature and its variability. We distinguish between intrinsic and trend-induced variability. Moreover, the dependence on the size of the integration domain and the improvement brought about by the nested RCM compared to the driving GCM are analysed. Both the evaluation of temperature means and variability and the evaluation of their changes confirm that RCM simulation on a larger domain often differs more considerably from driving GCM than simulation on a smaller domain. The larger domain simulation usually produces smaller biases for mean temperature but has worse agreement with observations in terms of variability. Further, the areas with the greatest discrepancies are often in the south-eastern region. In addition, noticeable differences between RCM and GCM simulations mostly emerge for the Alpine region and eastern regions. A possible explanation is the complex terrain and larger distance from domain boundaries. Moreover, it was analysed whether removing of the linear trend enhances the representation of changes in variability. This was not generally confirmed. Only in summer the simulations underestimated the observed increase in intrinsic variability less considerably than for total variability. However, biases were still considerable in many cases.