Event Abstract Back to Event Measuring infant response to early adverse events in the mouse Francesca R. D-Amato1*, Carlo Cinque1, Valentina Lampis2, Diego Oddi1, Claudio Zanettini1 and Anna Moles1 1 CNR Institute for Neuroscience, Italy 2 San Raffaele University, Italy The role of early environment in affecting vulnerable genotypes and precipitating psychopathologies during development and in adult life has been well documented in humans. Animal models of adverse life experiences have been established using pre and/or postnatal stressful events. Maternal behaviour during the early postnatal days has been analysed in details as possible mediator of the long lasting behavioural and physiological responses in the adult offspring. Contrary to rat, mouse maternal behaviour seems less flexible and less responsive to stressed-pups’ requests. This absence of changes in maternal behaviour in mice also when facing a challenging environment could be due to low pups responsiveness to the stress procedure, to low maternal responsiveness to stressed pups, or to a more general disruption of mother-infant relationship. While maternal behaviour has been extensively studied, infant’s behaviour offers fewer possibilities of investigation, due to the immaturity of the pup at birth. However, both the olfactory and the ultrasound communicatory systems are already functional in pups to build and establish the attachment bond with the caretaker. The analysis of the mother-infant bond, from the pup´s “viewpoint”, will be performed in response to different postnatal environmental and/or pharmacological treatments. Ultrasonic vocalizations in response to isolation, olfactory discrimination and attraction by nest/mother cues will be used as measures of infant attachment bond during development. This approach could shed light on long-term disruptive effects of neonatal stressful treatment in mice when no apparent changes in maternal behaviour occurred. Conference: 41st European Brain and Behaviour Society Meeting, Rhodes Island, Greece, 13 Sep - 18 Sep, 2009. Presentation Type: Poster Presentation Topic: Poster presentations Citation: D-Amato FR, Cinque C, Lampis V, Oddi D, Zanettini C and Moles A (2009). Measuring infant response to early adverse events in the mouse. Conference Abstract: 41st European Brain and Behaviour Society Meeting. doi: 10.3389/conf.neuro.08.2009.09.126 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 08 Jun 2009; Published Online: 08 Jun 2009. * Correspondence: Francesca R D-Amato, CNR Institute for Neuroscience, Rome, Italy, francesca.damato@cnr.it Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Francesca R D-Amato Carlo Cinque Valentina Lampis Diego Oddi Claudio Zanettini Anna Moles Google Francesca R D-Amato Carlo Cinque Valentina Lampis Diego Oddi Claudio Zanettini Anna Moles Google Scholar Francesca R D-Amato Carlo Cinque Valentina Lampis Diego Oddi Claudio Zanettini Anna Moles PubMed Francesca R D-Amato Carlo Cinque Valentina Lampis Diego Oddi Claudio Zanettini Anna Moles Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.
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