PURPOSE Economic growth is influenced by the changes in indirect taxes imposed by the government on the production/consumption of goods. This paper aims to identify the empirical relationship between indirect taxes – i.e., federal sales tax, federal excise duty, and customs duty – and the economic growth of Pakistan. METHODOLOGY For this purpose, annual time series data from 1972 to 2018 are used. The objective of the study is to evidence the long-run and short-run relationships of federal sales tax, federal excise duty, and customs duty with economic growth. The Augmented Dickey-Fuller unit root tests are used to check the stationarity of each variable. The Johansen Cointegration Test is performed to identify the cointegration among variables. The Vector Error Correction Model (VECM) is used to estimate the long-run and short-run relationships among these variables. FINDINGS The results of the study show that there are two cointegrating equations among variables. GDP Lag5, GDP Lag6, ST Lag1, ST Lag5, and FE Lag4 possess a positive impact on the economic growth of Pakistan. However, GDP Lag2, FE Lag6, and CD Lag7 have a negative impact on the economic growth of Pakistan. Previous years’ deviations from long-run equilibrium are corrected in the current year at an adjustment speed of 33% and 18% for GDP and ST, respectively. CONTRIBUTION/IMPLICATIONS Since the sales tax has a positive impact on economic growth, whereas federal excise duty and customs duty have a negative relation, it is advisable to form policies that contribute to economic growth instead of restricting it. As of the published statistical records of 2018, sales tax, federal excise duty, and customs duty contribute 65 per cent, 9 per cent, and 26 per cent, respectively, to the total indirect taxes. This collection structure is required to be rationalised to boost economic growth.