Nanofluids is a new type of efficient cooling mass. In the present experimental work, a new SiO2-ethylene-glycol/deionized water nanofluids with excellent static storage and dynamic stability was prepared. The static storage and high temperature dynamic stability of the nanofluids was investigated experimentally (particle size measurements, TEM photographs, Zeta Potential experiments). The corrosion resistance of nanofluids was investigated by means of aluminium pump cavitation experiments. The effects of concentration, temperature and Reynolds number on the thermophysical properties and heat transfer efficiency of nanofluids were studied. Based on the thermophysical parameters (thermal conductivity and viscosity) of nanofluids at different temperatures, the experimental correlations were fitted. The results show that the stability period of the nanofluids is more than 36 months. The convective heat transfer coefficient can be increased by more than 36.1% with the addition of 6 wt% nanofluids at 25 °C. The nanofluids provides improved heat transfer and good corrosion protection and impact resistance.