It is well known that differential equations with piecewise constant arguments is a class of functional differential equations, which has fascinated many scholars in recent years. These delay differential equations have been successfully applied to diverse models in real life, especially in biology, physics, economics, etc. In this work, we are interested in the existence and uniqueness of asymptotically almost periodic solution for certain differential equation with piecewise constant arguments. Due to the particularity of the equations, we cannot use the traditional method to convert it into the difference equation with exponential dichotomy. Through constructing Cauchy matrix of the investigated system to find the corresponding Green matrix of the difference equation, we need the concept of exponential dichotomy and the Banach contraction fixed point theorem of the corresponding system. Then we give some sufficient conditions to obtain the existence and uniqueness of asymptotically almost periodic solutions for these systems.
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