A nalytical Chemistry editors have called into question a study published last spring that claims to have detected high levels of potentially harmful platinum in the tissues and body fluids of women exposed to silicone breast implants. The study authors, Ernest D. Lykissa and Susan V. M. Maharaj, implicated a platinum- based silicone cross-linking catalyst as the source of the metal, which they reported to have detected in unusually high oxidation states—as high as +6 (C&EN, April 17, page 11). Upon publication of the study, silicone chemists raised questions regarding the team's ion chromatography methods. They noted, for example, that the highly oxidizing sample-preparation conditions and the absence of analytical standards in the study cast doubt on the team's ability to assign oxidation states accurately. In an editorial, Analytical Chemistry Editor Royce W. Murray and Associate Editor Catherine C. Fenselau write that the paper's results might be correct, but the presumption that the oxidation states ...