Case Of Fibroadenoma Research Articles

A Case of FIBROADENOMA Cured with Individualized Homoeopathic Medicine- Evidence Based Homoeopathy

Introduction: Fibro-adenomas are the most common benign tumor of female breast having distinct clinical and Histopathological findings. This case report of fibroadenoma highlights clinical presentation along with proper investigation reports like ultrasound, individualized homoeopathic treatment provided and ongoing follow-up. Palpable mass, nodular swelling, pain, redness and changes in the breast appearance along with fibrous and glandular tissue components are emphasized for proper diagnosis. Homoeopathic literature shows that case of fibro-adenoma had been successfully treated with individualized homoeopathic medicine. Individualized homoeopathic approach to breast fibro-adenoma ensures improved outcomes in mental, emotional as well as physical wellbeing. Case summary: The case report presented here wasa 23 year old female patient, from Repertory OPD, Homoeopathy Hospital, North Eastern Institute of Ayurveda and Homoeopathy, Shillong. The patient was treated with individualized homoeopathic medicine (Phosphorous30, 200) for one year, with significant improvement and progressively decreases in size of tumor.

Cytohistological Evaluation of Unusual Male Breast lesions: A Case Series from a Tertiary Care Centre

Introduction: Pathologic lesions of male breast are not as common as its female counterpart.In this study we have reported six cases of unusual pathological lesions of male breast presenting clinically asbreast lump studied by Fine Needle Aspiration Cytology (FNAC) with histologic correlation.Method: 6 male patients were studied who presented to us with breast lump and had FNAC done with subsequenthistopathological correlation.Result: Out of 6 cases, 3 were fibromatosis (desmoid-type), 2 cases of invasive carcinoma involving both breastswith axillary lymph node metastasis and 1 case of complex fibroadenoma were reported. In all of the above casesdefinitive diagnosis was given on FNAC with subsequent histopathological confirmation except for fibromatosisin which the diagnosis was benign breast lesion on FNAC.Conclusion: FNAC being a fast and cheap diagnostic tool proves to be a reliable diagnostic method for evaluationof breast lumps at an earliest with excellent histologic reproducibility.

Spontaneous fibroadenoma in a twenty-one-week-old female Wistar rat – a case report

We describe the characteristic macro- and microscopic findings of a new case of spontaneous fibroadenoma in a 21-week-old, non-treated female Wistar rat. A mobile and non-ulcerated mass was detected affecting the caudal inguinal mammary gland. At necropsy, the mass was 5.5 cm in size, spherical in shape, and well demarcated with a smooth surface. The cut surface was pink, with a multilobulated pattern. Microscopically, fibroadenoma was composed of dense connective tissue surrounding luminal epithelial tissue, organized in tubular structures. The luminal epithelial cells were typical and, in some areas, presented lipid vacuoles in the cytoplasm and proteinaceous material in the lumen of the tubules. The interlobular and intralobular stroma showed variable amounts of mast cells. Immunohistochemically, epithelial cells expressed both oestrogen and progesterone receptors in the nucleus. Fibroadenoma is a frequent tumour, but it is uncommon at an early age.

Клинический случай гигантской фиброаденомы у 13-летней девочки. Особенности диагностики

The article describes a clinical case of giant fibroadenoma in a 13-year-old girl, whose size was 20 cm, as well as a brief review of the scientific literature on benign neoplasms of the mammary glands in young patients. Giant fibroadenomas account for 0.5 to 2% of all fibroadenomas. In children and adolescents, ultrasound of the mammary glands is the main method of diagnosing fibroadenoma. Fibroadenoma needs to be differentiated from a phylloid tumor, which is clinically no different from fibroadenoma, but at the same time it has a high risk of malignancy. To make a final diagnosis, a puncture fine needle aspiration biopsy is additionally perform

Fibroadenoma Excision under Thoracic Segmental Spinal Anaesthesia in Isolated Situs Inversus Totalis: A Case Report

Situs inversus totalis is a rare congenital positional anomaly with a predicted incidence of 1: 10,000 amongst the general population described by the transposition of the abdominal and thoracic visceral structures. Local infiltration of the breast is a common technique for fibroadenoma of small sizes. However, its efficacy, including duration of action as well as the extent, can be unreliable and surgeon dependent. Unless otherwise contraindicated, the regional technique of thoracic segmental spinal anesthesia has been proven to be a safe and effective method for even major surgeries including laparoscopic cholecystectomy, breast lumpectomy and abdominal surgeries. Multiple regional anesthetic techniques are available and should be used according to the requirement of the surgery as well as the skill and knowledge of the performing anesthetist. We discuss here, a case of fibroadenoma in a patient with isolated situs inversus totalis, operated under thoracic segmental spinal anesthesia.

A case of fibroadenoma of the breast cured by constitutional remedy

A case of fibroadenoma of the breast cured by constitutional remedy

GIANT TUBULAR ADENOMA OF BREAST IN A YOUNG NULLIPAROUS FEMALE: A CASE REPORT

Background: Tubular adenoma of breast is an uncommon benign condition in young females, with only few growing to a very large size. Triple assessment tools shows similar presentation as a fibroadenoma, however, only excision biopsy can differentiate tubular adenoma from fibroadenoma. Methods: A case of giant lump in 18 years young, unmarried, nulliparous female presented in outdoor patient department of a medium size trust hospital of Lahore, Pakistan and was preoperatively diagnosed as a case of fibroadenoma. Results: Postoperative excision biopsy report showed a rare pathology of giant tubular adenoma of breast. Conclusions: Giant tubular adenomas are rare clinically in nulliparous young females and should be considered in differential diagnosis of breast lumps among young, nulliparous females and a long-term follow-up of patients is required to observe its potential for recurrence and malignancy.

Juvenile fibroadenoma of the breast

Juvenile fibroadenoma is a rare variant of fibroadenoma and is characterized by rapidly enlarging, painless, and unilateral masses. We presents a case of juvenile fibroadenoma of the breast in a 14 year old girl, presented with rapidly growing mass in the right breast of four months duration. On local examination a solitary, firm, mobile, unilateral, non-tender mass was felt in the upper and lower outer quadrant of the right breast, measuring 6.5 x 4.1 x 3.5cm. The overlying skin was normal. There was no axillary lymphadenopathy. The sonomammography of the right breast showed a single, oval, hypoechoic, well circumscribed mass lesion with cleft like spaces features suggestive of complex fibroadenoma BIRADS IV a. On fine niddle aspiration cytology showed sheets of hyperplastic benign ductal epithelial cells with myoepithelial cells and a background of benign bipolar nuclei and blood, without inflammatory cells. It was suggestive of fibroadenoma. She underwent right lumpectomy with breast conservation. We received right breast lumpectomy specimen. On gross showed a well-circumscribed, grey white, firm mass m 6.3 x 4.1 x 3.2 cm. On histologic features reported as juvenile fibroadenoma right breast. The postoperative period was uneventful and she recovered well and advise regular follow up. Juvenile fibroadenomas are rare benign breast tumors that should be distinguished from other masses of breast. Herewith we are presenting case of Juvenile fibroadenoma for its clinical, radio imaging, pathological features and management.

Fibroadenoma in axillary accessory breast tissue: a case report

BackgroundAccessory breast(s) is defined as the presence of more than two breasts with or without a nipple and areola in human beings. It may occur anywhere along the primitive embryonic milk lines, which extend from the axilla to the groin. Accessory breast tissue can potentially undergo the same physiological and pathological processes as the normally located breast, including lactational change, fibroadenoma, and carcinoma. Although common in the normally located breast tissue, the incidence of fibroadenoma in accessory breast tissue is rare. Furthermore, if the swelling occurs in the axilla or groin, it may present a diagnostic challenge by clinically mimicking a lymphoma or other causes of lymphadenopathy. Owing to its rarity and its tendency to pose a clinical diagnostic challenge, we decided to report a case of fibroadenoma in axillary accessory breast.Case presentationA 28-year-old Ethiopian female patient came to University of Gondar comprehensive specialized hospital with a complaint of left axillary swelling of 3 years duration. There was no history of cough, fever, weight loss, or night sweating. On physical examination, there was an approximately 5 × 4 cm, firm, well-defined, mobile, nontender solitary mass in the left axilla that was completely separated from the left breast. Fine-needle aspiration cytology suggested a diagnosis of fibroadenoma in axillary accessory breast tissue. The mass was completely excised, and histopathologic examination confirmed the diagnosis. Her recovery was uneventful. She was informed about the diagnosis, reassured, and discharged from care.ConclusionIn the clinical evaluation of a patient with axillary swelling, accessory breast tissue disorders such as fibroadenoma must be considered as a differential diagnosis for early diagnostic workup and management. Moreover, this case underscores the fact that, similar to normal breast tissue, accessory breast tissue is also susceptible to the same pathologic disease processes including neoplasms such as fibroadenoma.

A Rare Case of Fibroadenoma in an Accessory Breast over Anterior Chest Wall

Accessory breast tissue is an uncommon condition which occurs in 0.4–6% of women. It is mostly located in the axilla where it can cause diagnostic difficulty, especially if it is unilateral and large. Usually it is bilateral and presents as an asymptomatic mass during pregnancy or lactation. The diagnosis of ectopic breast tissue is important as it can undergo the same pathological changes that occur in a normal breast, such as mastitis, fibrocystic disease and carcinoma. We present a case of unilateral accessory breast without nipple and areola over anterior chest wall with a fibroadenoma inside it in a 20 year old lady.

Rare Case of Fibroadenoma within Ectopic Breast Tissue in Axilla – A Case Report and Review of Literature

The congenital anomalies of breast, especially the polymastia (supernumerary breast) and polythelia (supernumerary nipple), can have varied presentations, associated renal anomalies, and pathologies arising from them. The axillary polymastia is a variant of ectopic breast tissue (EBT). Ectopic breast tissue can undergo the same physiological and pathological processes as the normally located breast. The incidence of fibroadenoma developing in ectopic breast is reported as a rare entity, the most common being the carcinoma. Here we report a case of fibroadenoma developing in ectopic breast tissue located in axilla.

Fibroadenoma arising in accessory breast tissue of the axilla: A rare case report

Axilla is the most common site for accessory breast tissue. Fibroadenoma is a very common benign lesion of breast but is not commonly found in accessory breast tissue. We report a case of fibroadenoma in a 19-year-old young unmarried girl who presented with a mobile swelling in left axilla since five months. The ipsilateral breast was normal. No FNAC was performed and excision biopsy was done and sent for histopathological examination which showed features of fibroadenoma. The most important clinical significance is that number of inflammatory, cystic and neoplastic diseases similar to those of a normal breast have also been reported in accessory breasts. For early detection of malignancy in the axilla, a vigilant self-examination and clinical assessment is required. Keywords: Fibroadenoma, Accessory breast, Ectopic breast tissue.

Giant fibroadenoma mimicking phylloides tumor in post-menopausal female: a case report and review of literature

Giant fibroadenomas are rare breast lesions in elderly women especially post-menopausal women and accounting for 0.5-2% of all cases of fibroadenomas. They pose diagnostic as well as therapeutic challenge because resemblance of its clinical and imaging features with other breast lesions, especially phylloides tumor. We present a rare case of giant fibroadenoma of breast in postmenopausal female of 53 year of age mimicking phylloides tumor. Ultrasonography and fine needle aspiration cytology (FNAC) suggestive of fibroadenoma. Tumor was completely excised and diagnosis of giant fibroadenoma was confirmed by histopathology. Breast conserving surgery is the gold standard treatment.

Rare findings in a common tumor: A case of complex fibroadenoma with secondary changes in a young female

Fibroadenoma (FA) is one the most common breast tumours seen in adolescent and young women. Although, in the postmenopausal females FA regresses, becomes hyalinised and shows calcification these findings are rare in the younger and reproductive age group. Complex FA is defined as FAs with cysts, sclerosing adenosis, epithelial calcifications or papillary apocrine changes. We present a case of multiple synchronous FAs in a young female with uncommon findings at her age like extensive hyalinization, coarse calcification and cystic changes. No evidence of ductal hyperplasia, carcinoma in situ or invasive carcinoma was seen. Very few such cases have been reported in literature in young females. Despite these unusual findings, recent large cohort studies concluded that complex FA is not an independent risk factor for carcinoma breast.

A rare case of fibroadenoma in ectopic breast tissue of axilla: case report

Developmental abnormalities of breast can lead to formation of ectopic breast tissue which may present as polymastia or polythelia or in form of swelling along the milk line. Ectopic breast tissue can also develop pathological changes similar to normal located breast tissue. This report is about a case of fibroadenoma developing in ectopic breast tissue of axilla. A thirty-four-year-old female presented with painful swelling in right axilla for 2 years and was diagnosed with fibroadenoma of axillary tail of right breast. Excision biopsy of the swelling confirmed the diagnosis of fibroadenoma. Fibroadenoma must be considered for any axillary swelling along with other differential diagnoses like lymphadenopathy, carcinoma arising from ectopic breast tissue, lipoma, sebaceous cyst, tuberculosis, vascular lesions, cutaneous malignancies or secondaries in lymph nodes. Ectopic breast tissue should be subjected to similar evaluation and screening as is recommended for normally located breast tissue. The patient should also be evaluated for possibility of kidney and urinary tract malformations.

A rare unilateral giant fibroadenoma of the breast during pregnancy and lactation

: Fibroadenomas are the most common breast masses in adolescent women. Giant fibroadenomas are an uncommon disease during pregnancy and lactation. Significant enlargement might result in breast asymmetry and deformity. We present a rare case of giant fibroadenoma during pregnancy and lactation with significant breast asymmetry. Excision with round block technique leaves a discrete scar and a cosmetic contour.

A rare unilateral giant fibroadenoma of the breast during pregnancy and lactation

Fibroadenomas are the most common breast masses in adolescent women. Giant fibroadenomas are an uncommon disease during pregnancy and lactation. Significant enlargement might result in breast asymmetry and deformity. We present a rare case of giant fibroadenoma during pregnancy and lactation with significant breast asymmetry. Excision with round block technique leaves a discrete scar and a cosmetic contour.

Giant Fibroadenoma of Breast: A Diagnostic Dilemma in a Middle Aged Woman

Giant breast masses are entities of great concern as they continue to pose a diagnostic as well as a therapeutic challenge We present a case of giant fibroadenoma of the right breast in a year old woman which simulated as a phyllodes tumor creating a diagnostic conundrum

11 歳女児に発生した乳腺巨大線維腺腫の 1 例

11 歳女児に発生した乳腺巨大線維腺腫の 1 例

Low Grade Well-circumscribed Well Differentiated Liposarcoma Developed in Fibroadenoma with Stromal adipose differentiation of the Breast; A Case Report

Fibroadenomas are the most common breast tumor in adolescents and young women.They comprise 20% of benign breast masses and 12% of all breast masses in postmenopausal women. Smooth muscle metaplasia and adipose differentiation are uncommon forms of stromal differentiation encountered in a minority of fibroadenomas. Liposarcoma can arise from pre-existing benign lesions like phylloides tumour or from lipoid tissue in the breast. In this article we present a case of 38 year-old female who presented with a right breast mass which was clinically diagnosed as a case of fibroadenoma, but histologically showed a low grade well-circumscribed liposarcoma discovered in a pericanalicular type of fibroadenoma with stromal adipose differentiation. According to our knowledge, this the first case of a well-circumscribed liposarcoma arises in fibroadenoma of the breast. Virtual Slides: www.diagnosticpathology.eu/vs/2016_2_100/