Case Of Epidermal Cyst Research Articles

Clinical Analysis of Auricular Tumors

Background and Objectives Various distinct types of tumors can develop in the auricles; however, those have not been thoroughly studied clinically. The aim of the study is to assess the clinical nature of auricular tumors.Subjects and Method We retrospectively reviewed medical records and pathological findings in patients with auricular tumors who underwent surgical interventions at a single institution from January 2011 to October 2023. Cases in which the location of the tumor could be identified and pathological results were confirmed were included. We analyzed age, sex, tumor location and size, tumor occurrence period and causes, recurrence, and pathological results.Results A total of 98 auricular tumors were included in the study. Auricular tumors were most commonly found on the lobule (32.3%), followed by the helix (30.1%) and the posterior auricle (15.1%). The most prevalent pathological type of auricular tumors was an epidermal cyst (45.2%), followed by keloid (21.5%). A single case of squamous cell carcinoma was reported. Eight tumors recurred following surgical resection, with five cases of keloid, two cases of epidermal cyst, and one case of squamous cell carcinoma, with an average recurrence interval of 6.1 months.Conclusion The present study assessed the largest number of auricular tumors collected in a single institution. Tumors with diverse clinical characteristics can develop in the auricle, and cosmetic considerations must be taken into account before undergoing surgical treatment. The findings of the present study could provide proper approaches to the auricular tumors.

Clinicopathological Spectrum of Vulvar Lesions-A Retrospective Study

Introduction: Vulvar lesions constitute a wide spectrum ranging from non neoplastic inflammatory lesions to malignancies. Some show nodular masses and others remain asymptomatic. This poses challenges to clinicians in differentiating non neoplastic inflammatory dermatoses from benign and malignant lesions. Along with the clinical history and physical examination, a biopsy of the lesion plays an important role in proper diagnosis and treatment. Aim: The aim of the present study was to identify the morphological spectrum of vulvar lesions with clinical and histological findings. Materials and Methods: This was a retrospective observational study conducted in the Konaseema region of India for two years from January 2019 to January 2021. A total of 85 female patients with vulvar lesions were included in the study. Biopsy samples were obtained from all the 85 cases and were formalin-fixed, routinely processed, and paraffin embedded. Haematoxylin and Eosin (H&E) staining was done. Special stains were done wherever necessary. The results were analysed using Microsoft excel. Results: The age of patients ranged from 18 to 88 years. The most common age of patients was in the 4th decade (30 cases amounting for 35.29%). The mean age of the study population was 39.5±15 years. Among the 82 cases, 40 (48.78%) were non neoplastic lesions, and 42 (51.21%) were neoplastic lesions. Among the neoplastic category, 27 (64.2%) were benign lesions and 15 (35.71%) were malignant lesions. The non neoplastic category included five infections (12.5%) and 35 non infectious inflammatory lesions (87.5%). The infections included one case of MC and 4 cases of condyloma acuminatum. The non infectious, and non neoplastic inflammatory lesions included 10 cases of Lichen Sclerosus Atrophicus (LSA), one case of Lipomatoushamartoma, four cases of Lichen planus, six cases of epidermal cysts, 10 cases of Bartholin cysts and four cases of Gartner duct cyst. The benign lesions in the neoplastic category included four cases of Hidradenomapapilliferum, four cases of Aggressive Angiomyxoma (AA), 12 cases of Fibroepithelial Stromal Polyps (FEP), and a case of Leiomyoma. The malignant lesions included 14 cases of squamous cell carcinoma and a case of extramammary Paget’s disease. Conclusion: Vulvar lesions can be due to eclectic causes and pose a diagnostic difficulty both clinically and histopathologically due to their similar presentation. Thorough clinical and pathological examination along with proper clinicopathological correlation is required for accurate diagnosis and treatment.

Reconstruction of facial skin defects by the V-Y subcutaneous pedicle flap

Objective: To investigate the method and efficacy of reconstruction of facial skin defects after removing the lesions by applying the V-Y subcutaneous pedicle flap. Methods: A retrospective analysis was performed on 23 patients with facial reconstruction by using V-Y subcutaneous pedicle flap in the Otolaryngology Department of Guangdong Integrated Traditional Chinese and Western Medicine Hospital from March 2012 to April 2021. Patient ages ranged from 45 to 85 years old, with a mean age of 66.5 years (14 males and 9 females). The facial lesion sites included cheek in 12 cases (nearly lower eyelid in 4 cases), nose in 4 cases, lips in 3 cases, temporal in 2 cases and mental region in 2 cases. The initial pathology included malignant tumors (7 cases of basal cell carcinoma (BCC), 2 cases of squamous cell carcinoma(SCC), and 1 case of malignant melanoma) and benign lesions (7 cases of keratoderma, 3 cases of intradermal nevus, 1 case of pilomatricoma, 1 case of cutaneous mixed tumor and 1 case of epidermal cyst). The V-Y subcutaneous facial pedicled flaps were designed reasonably after the facial lesions were excised. The advantages of blood supply, survival rate and adverse events of the flap were analyzed Chi-square test was used to compare the observation results of different types of patients. Results: The primary focus of 23 patients was excised surgically, and intraoperative frozen-section examinations were performed for obtaining margins negative as far as possible. One positive margin was still found in 1 patient after multiple resection in our group. The defect sizes were 14 mm×12 mm-59 mm×54 mm. All the flaps survived. The adverse events were slight necrosis of the epidermis at the junction or vicinity of the three arms of "Y" shaped in 4 cases, but the wounds finally recovered by wet compress and dressing change. There were no significant differences in the incidences of adverse events between double and single pedicle flaps (4/19 vs. 0/4), between benign and malignant lesions (4/13 vs. 0/10), and between patients with and without underlying diseases (1/6 vs. 3/17) (χ2 values were 0.98, 3.56, 0.01, respectively, all P>0.05). There were no other major complications such as dehiscence, hematoma, eyelid ectropion and lip deformation. The patients with benign lesions were followed-up at least for 3 months, while those with malignant tumors were followed-up for 6-36 months postoperatively, without recurrence. Conclusions: V-Y subcutaneous facial pedicled skin flap may be a "no-easy-necrotic" local flap in the repair of small and medium-sized facial defects.

A rare case of epidermal cyst of hand with review of literature

Epidermoid cysts commonly occur in the soft tissues in a subcutaneous location as a result of trauma or surgery. They are benign cystic lesions that have a good outcome after excision. Here we present a case of epidermal cyst of hand in 56 year old male patient. X-ray demonstrated a soft tissue swelling without bony involvement on the palmer aspect at the level of middle phalanx of the right middle finger. MRI report was suggestive of round to oval lobulated well defined lesion seen on the palmer aspect of right middle finger measuring 3.1x1.6 cm. We present its further management and review of literature.

伴淋巴细胞带状浸润的表皮囊肿一例

伴淋巴细胞带状浸润的表皮囊肿一例

Keystone-designed buried de-epithelialized flap: A novel technique for obliterating small to moderately sized dead spaces.

Effective obliteration of dead space after reconstructive surgery facilitates a good cosmetic outcome and prevention of delayed wound healing and recurrent infection.We evaluated the efficacy of a keystone-designed buried de-epithelialized (KBD) flap for the obliteration of small to moderately sized surgical dead spaces.We reviewed the medical records of patients who received a KBD flap following removal of a mass or debridement of necrotic tissue from September 2015 to February 2016. The diagnosis, site, dead space dimensions, flap width, drain data, complications, and follow-up duration were recorded.Twenty-eight KBD flaps were evaluated, including 9 cases of fat necrosis, 7 cases of epidermal cyst, and 12 cases of lipoma. Dead space dimensions ranged from 2 × 1.5 × 1 cm to 10 × 5 × 3 cm, with a mean depth of 2.01 cm. Flap sizes ranged from 2.5 × 1 cm to 11 × 3 cm, with a mean flap width of 2.01 cm. No postoperative complications, such as seroma or hematoma, occurred. The cosmetic results were favorable, and all patients were satisfied with their final outcomes.The KBD flap is useful for the obliteration of small to moderately sized surgical dead spaces both spatially and physiologically and shows excellent cosmetic outcomes.

A Case of Epidermal Cyst with Ossification

A Case of Epidermal Cyst with Ossification

Transsacrococcygeal Approach for Resection of Retrorectal Tumors

Retrorectal tumors, are a rare and interesting entity, traditionally managed with surgery. The surgical approach is a key to get an easy and safe access. The purpose of this study was to evaluate the results of resection by a transsacrococcygeal approach. Thirty-six patients had retrorectal tumors resected by a transsacrococcygeal approach in our department. All the tumors were en bloc resected, irrespective of size and anatomical depth. The clinic data were retrospectively reviewed. Tumor mean size was 10 ± 4.4 cm. In 16 cases, tumors were 10 cm or more in size. The largest tumor measured 20 cm. The estimated mean blood loss was 130 ml. No mortality and severe postoperative complications were observed. The most significant issues were wound infection and delayed healing. Pathology showed 15 cases of epidermal cysts, two cases of enterogenous cyst, one case of bronchogenic cyst, 12 cases of teratoma, two cases of schwannoma, two cases of low-grade malignant fibrous myxoma, one case of aggressive angiomyxoma, one case of desmoid tumor. The transsacrococcygeal approach gives an easy access and good visualization with fewer complications. This surgical approach shows to be safe and effective for resection of retrorectal tumors.

Epidermal cyst of breast: A rare case entity

Epidermal cyst arising from breast is an uncommon benign condition. We report two cases of epidermal cyst of the breast on fine needle aspiration one in male and other in female patient in their forties. Epidermal cyst of breast presents as an enlarging lump in the breast and mimics a benign breast lesion, most commonly fibroadenoma. Excision is usually recommended for a definite histopathological diagnosis and for the prevention of potential risks of malignant transformation.

Cistos epidermais em ovinos

São descritos os aspectos clínico-patológicos de cistos epidermais em quatro ovinos, com idade entre dois e 12 anos, oriundos da região central do Rio Grande do Sul, Brasil. Três desses ovinos apresentavam múltiplos nódulos cutâneos, distribuídos aleatoriamente pelo corpo, e um ovino apresentava nódulo cutâneo solitário na região cervical. O período entre o aparecimento do primeiro nódulo e o surgimento de múltiplos nódulos foi de oito meses, em um caso, e um ano, em dois casos. Os quatro ovinos eram os únicos animais afetados em seus respectivos rebanhos. Os nódulos cutâneos eram redondos ou ovais, salientes, flutuantes, não pruriginosos e recobertos por pele parcialmente alopécica. Esses nódulos variavam de 1,0 a 7,0cm de diâmetro e, ocasionalmente, apresentavam um pequeno orifício central, com 1-2mm de diâmetro, na superfície externa. Ao corte eram císticos, delimitados por uma parede fina e branca, com 0,5-0,8cm de espessura, e preenchidos por material branco ou amarelado e friável. Histologicamente, os cistos eram revestidos por epitélio, contendo todos os estratos de um epitélio escamosos estratificado, sobre uma fina cápsula de tecido conjuntivo fibroso denso. Os cistos eram preenchidos por agregados homogêneos e feixes de ceratina, arranjados de forma concêntrica. Baseado na localização e características macroscópicas e histológicas esses cistos foram diagnosticados como cistos epidermais infundibulares.

An Unusal Case of Epidermal Cyst in Submandibular Space

Epidermal cysts are very common skin lesions and 1.6% are seen in oral cavity. But epidermal cyst in submandibular region is extremely rare with only 3 such reported cases in last 25 years. Here we present a rare case of epidermal cyst in left submandibular space in a 53-year-old female.

Epidermal Cyst on the Sole

Epidermal Cyst on the Sole

Case of epidermal cyst on the glans penis

Case of epidermal cyst on the glans penis

Male Breast Lump: Case Report of Epidermal Cyst of the Breast

INTRODUCTION: The intramammary epidermal cyst is rare. Its localization more common is back, neck and scalp. Mammograms and ultrasound can be variable, mimicking benign and malign diseases. This diagnosis rarely is suspected. The etiology is diverse: congenital, trauma (including breast surgery), occluded hair follicles, otherwise associated to fibroadenoma or fibrocystic disease when ductal ectasia is present. It can evolve and increases until rupture with pain, inflammatory process or abscess. These complications can be seen after breast surgical procedures for aesthetical, diagnostic or therapeutic reasons. The resection of epidermal cyst is diagnostic and therapeutic. CASE REPORT: A 45 years-old man has presented right breast painful lump since November 2010 associated to growing, purulent nipple discharge and flogistic symptoms which regressed spontaneously. He has never taken any drug. Physical examination has showed retroareolar lump in right breast measuring 2 cm, nipple discharge and without axillary lymphadenopathy. In December 2010, ultrasound revealed right retroareolar, irregular, hipoecogenic nodule measuring 2. 7 cm. In February 2011, the needle aspiration sample was suggestive of mammary cyst. In March 2012, mammogram showed right retroareolar, regular nodule measuring 5 cm and BI-RADS 0. He had normal exams: renal and hepatic biochemical exam; thyroidal and sexual hormones; and tumoral markers to testicular neoplasia. In Juny 2012, the resection was carried out and histopathological study was epidermal cyst and organizing abscess. DISCUSSION: We describe a rare case of epidermal cyst in man. This disease can appear in any age and your frequency is unknown. Most similar cases in literature were female. In this report, gynecomastia was excluded and clinical and radiological findings have suggested fibroadenoma. The differential diagnosis with epidermal cyst is difficult and uncommon for the reason that it can imitate benign and malign lesions. The histopathological study is the best to define it. The epidermal cyst can degenerate in squamous carcinoma: 0.5 to 19%. When treated, the epidermal cyst has an excellent prognosis.

Epidermal cyst of the bony external auditory canal in an adult

To present a rare case of epidermal cyst of the bony external auditory canal (EAC) in an adult. Epidermal cyst of the bony EAC, although very rare, should be kept in the list of differential diagnosis of a skin-lined mass of the EAC. Epidermal cyst is very rare in the EAC. Only two cases of epidermoid cyst arising from the bony EAC are reported previously in English, but both were in pediatric age group. Epidermal cyst in EAC in adult patients may be confused with masses that are commonly seen, and these include osteomas, exostosis, ear polyps, carcinomas, etc. Epidermal cyst should be included in the differential diagnosis of a patient with an ear mass.

Epidermal Cysts in a Tacrolimus Treated Renal Transplant Recipient

Tacrolimus, a calcineurin inhibitor, formerly also known as FK506, is a macrolactam drug isolated from Streptomyces tsukubaensis. Its mode of action closely parallels the action of cyclosprorin A (CsA) and can be used for the treatment of inflammatory and autoimmune skin diseases in which systemic CsA has proved effective against psoriasis, pyoderma gangrenosum, atopic dermatitis, lupus erythematosus and graft versus host disease (GVHD). Although several cases of epidermal cysts have been reported in patients using cyclosporine and other immunosuppressants after organ transplantation; such types of cases have yet not been reported after administration of tacrolimus. However, we report herein a case of presence of multiple, various sized epidermal cysts in a renal transplant recipient receiving tacrolimus.

Pelvic Epidermal Cyst of Round Ligament:The Role of Imaging Procedures for Minimally Invasive Laparoscopic Approach

Background: This article reports on one case of epidermal cyst (EC) of the round ligament (RL), in which imaging procedures were helpful for establishing a preoperative diagnosis. Case: A 30-year-old female was referred to the authors' institution with abdominal pain. The ultrasonography showed a hypoechoic, heterogeneous round mass adjacent to the uterine extremity of the left ovary, with a maximum diameter of 4.5 cm. Computed tomography revealed a round (6 cm maximum diameter) pelvic mass in the left side of the uterus, superiorly to the omolateral ovary. Laparoscopic resection of the mass was performed. Macroscopically, the mass measured 6 cm × 6 cm × 3.5 cm and had a smooth external surface. On cut section, the mass was shown to be a unilocular cyst, and the cavity was filled with soft, yellow, amorphous material. Histologically the lesion was lined by a stratified squamous epithelium. The cavity contained keratin material. After 20 months of follow-up, the patient was healthy without any symptoms of a recurrent tumor. Conclusions: If a pelvic mass is encountered adjacent to an ovary an EC of the RL should be included in the differential diagnosis. Imaging procedures may show the benign nature of the mass and the lesion may be removed with a minimally invasive laparoscopic approach. (J GYNECOL SURG 26:289)

Detection of human papillomavirus 60 in epidermal cysts of nonpalmoplantar location.

Human papillomavirus (HPV) types 57 and 60 are associated with epidermal cysts of palmoplantar location (PPECs). Recently, there was a report of HPV 60 in a wart located in a nonpalmoplantar area as a possible precursor of a nonpalmoplantar epidermal cyst (NPPEC). There has been no study that has examined the presence and frequency of HPV in ordinary NPPECs. We reviewed 63 cases of epidermal cysts, including 59 NPPECs and 4 PPECs. After routine histopathologic review, polymerase chain reaction (PCR) of extracted DNA, sequencing of PCR products, and, finally, a homology search were undertaken. As a result, 9 of 63 (14.3%) cysts, including 6 of 59 NPPECs (10.2%), showed a positive reaction on PCR. By homology search after PCR, all were demonstrated as HPV 60. For NPPECs, no variables, including some histopathologic features, are significantly related to the presence of HPV 60 in univariate or multivariate analysis (P > 0.05).

Molluscum contagiosum: histologic patterns and associated lesions. A study of 578 cases.

Molluscum contagiosum (MC) is rarely associated with other skin diseases, especially cutaneous neoplasms. Such associations are exceptional and of unknown frequency. The aim of this study was to record the histologic variants and frequency of associated lesions in a large series of consecutive MC cases. We reviewed 578 MC cases from the Laboratory of Dermatopathology of the University Hospitals of Strasbourg, France (1959-1999). The locations of MC were as follows: head and neck (34.7%), trunk (27.1%), lower limbs (20.7%), upper limbs (8.7%), and genitalia (3.8%). Molluscum contagiosum occurred more often in female patients (56.7%). The age range of patients included in this study was 0 to 19 years (34.9%), 20 to 39 years (31.1%), 40 to 59 years (22.8%), and over 60 years (6.5%). Histologic variants of MC were noted in 46 cases (31 pseudocystic, 8 giant, and 7 pedunculated). An underlying abscess was present in 65 cases. Of the 578 cases, 22 were associated with other lesions (3.8%). There were 9 cases of epidermal cysts, 4 of nevocellular nevi, 3 of metaplastic ossifications, 2 of true epidermal nevi, 2 of sebaceous hyperplasias, 2 of soft fibromas, and 1 of Kaposi sarcoma. Except in immunocompromised patients, such associations are likely to be coincidental. The clinical diagnosis was correct in 42.3% of the cases. Clinical accuracy varied according to the age, localization, and histologic pattern of MC. Pseudocystic MC, giant MC, and MC associated with other lesions were responsible for frequent clinical misdiagnosis.

Immunohistochemical observation of cytokeratins in keratinous cysts including plantar epidermoid cyst.

Sixteen cases of epidermal cyst (EC) (6 cases of conventional EC and 10 cases of plantar epidermoid cyst (PEC)) and 9 cases of trichilemmal cyst (TC) were examined by an immunohistochemical technique using various antibodies against cytokeratins and human papilloma virus (HPV) in order to clarify their histogenesis. There was no difference in immunoreactivities between EC and PEC with or without HPV infection. In TC, the inner layers of the cyst wall were stained with the antibody E3 (CK17), and the outermost layer was stained with the antibodies 4.1.18 (CK8) and 170.2.14 (CK19). In PEC and EC, however, the cyst wall didn't react with these antibodies, and differentiation-specific cytokeratins were expressed in the inner layer. These results confirmed that the immunoreactivities of PEC and EC were identical to those of normal epidermis or infundibulum, and that those of TC were similar to the outer root sheath between the lower infundibulum and isthmus. Although PEC has been recently reported to originate from eccrine ducts, there was a significant difference in immunoreactivities between PEC and eccrine ducts. Furthermore, on the basis of the fact that sole skin has no hair follicles, PEC was speculated to originate from epidermal implantation.