Purpose: Tissue-engineered strategies have gained considerable attention for the past decades to regenerate articular cartilage. The current approaches aim to develop scaffolds with sufficient mechanical strength by mimicking the structure and composition of the native tissue. Hence, the use of decellularized cartilage scaffolds appeared as most attractive since they fulfil both characteristics. To tailor decellularized cartilage scaffolds as an appropriate environment for cell ingrowth and chondrogenesis, mechanical properties, such as stiffness or elasticity, play a key role.