There are several studies on environmental contaminations due to active Uranium (U) mining and after decommissioning of U mines. However, there are very few information on environmental impacts due to U exploration and development (E&D). This lack of information hinders generating baseline data for future environmental health impact assessment, particularly during the active phase of mining. We conducted an extensive environmental sampling around a U E&D site in Labrador in 2013. We collected soil, water, sediment, leaves of wild plants and trees (Carex Aquatilis, Myrice Gale, Spruce and Alder), tree core (Spruce), and fish (Trout) samples. We also collected similar samples from control sites from a nearby area. The rationale behind the sampling was to explore the level of contamination and impacts on food chain, as local Aboriginal (Inuit) community frequently visit those sites for hunting, catching fish and collection of traditional foods like berries. We found very high level of U contamination (10 to 250 times more than the control sites) of water, sediments and plant samples from the actual E&D site. Mixture of stream water from the surrounding forest further diluted the contaminated water. Therefore, the level of contamination drastically fell beyond few hundred meters of E&D site. The E&D site is almost 25km from the nearest community. It showed that until now the contamination is still localized. As of now there is no immediate threat to human health; however the local authority should erect a fence around the highly contaminated site to prevent any animal contamination. Due to growing global demand for U, the E&D site will turn into fully functioning U mining in near future. The study has generated very rich baseline data for future environmental health impact assessment.