The present study was intended to measure the relationship between job stress and job satisfaction among nurses working for a general hospitals. The self-administered questionnaires were given to 312 nurses during the period from February 25 to March 16, 2013. As a results, the level of job satisfaction of subjects was significantly lower in high group than low group in job demand, but it was significantly lower in low group than high group in job control, supervisor support and coworker support. In correlations, job satisfaction were found to be in a negative correlation with job demand, whereas in positive correlation with job control, supervisor and coworker support. In logistic analysis, the odds ratio of job satisfaction on job demand were significantly increased in the high group than in low group, but job control supervisor and coworker support were significantly decreased in the high group than in low group. In hierarchial multiple regression analysis, the affecting factors to the job satisfaction was selected variables such as educational background, work station, subject satisfaction of work, career choice motives, turnover experience, job stress contents(job demand, job control, supervisor support and coworker support). especially, job stress contents was significantly increased of explanatory power of job satisfaction. It suggested that the level of job satisfaction got more power by addition of job stress contents.