Based on the goal of "dual-carbon" strategy, it is important to explore the impacts of land use change on carbon stock and the drivers of spatial differentiation of carbon stock in Xinjiang. Here, we predicted the land use types in Xinjiang in 2035 under different scenarios and analyzed the impacts of land use on carbon stock, which is of great theoretical and practical importance for policy formulation, land use structure adjustment, and carbon neutrality target achievement in Xinjiang. The coupled PLUS-InVEST-Geodector model was used to explore the spatial and temporal patterns of carbon stock change under the scenarios of rapid development, natural change, arable land protection, and ecological protection in Xinjiang in 2035 and to quantitatively reveal the attribution of influences on the changes in carbon stock from the perspectives of land use change and the combination of nature-socioeconomic-accessibility. The results showed that: ① From 1990 to 2020, the area of arable land and construction land in Xinjiang increased, and in terms of the transfer direction, it was mainly shifted from unutilized land to grassland. ② On the time scale, the carbon stock in Xinjiang showed the fluctuation of "decrease-increase-decrease," with an overall increasing trend. The transfer of unutilized land to grassland was the main reason for the increase in carbon stock; on the spatial scale, the carbon stock in the Altai Mountains in the north, the Tianshan Mountains in the middle, and the Kunlun Mountains in the south was higher, whereas the carbon stock in the Tarim Basin and the Junggar Basin was lower. ③ In 2035, the carbon stock of the natural development and rapid development scenarios decreased by 27.24 Tg and 71.17 Tg compared with 2020, respectively, and the ecological protection and arable land protection scenarios increased by 492.55 Tg and 46.67 Tg. The ecological protection scenario could significantly increase the carbon stock of the Xinjiang Region compared with that in the other scenarios, and the distribution pattern of the carbon stock in the four scenarios was more or less the same as that in 2020. In addition to land transformation, soil erosion intensity was the main driver of spatial differentiation of carbon stocks in Xinjiang (q value of 0.3501), followed by net primary productivity of vegetation. The results of multifactor interactions showed that the spatial differentiation of carbon stocks in Xinjiang was the result of the joint action of multiple factors. All the factors had a synergistic enhancement under the interactions. The interaction between soil erosion intensity and the net primary productivity of vegetation was the main driver of the spatial differentiation of carbon stocks in Xinjiang.