Bonded carbon fiber reinforced polymer (CFRP) confined concrete presents issues such as stress hysteresis and easy detachment at the interface between CFRP and concrete. Applying prestress to CFRP can improve this situation. To investigate the stress-strain behavior of prestressed CFRP strengthened plain concrete columns (PC) under axial compression, a total of 1 unreinforced concrete column, 9 bonded CFRP strengthened concrete columns, and 27 prestressed CFRP strengthened concrete columns were designed. Including CFRP layers and the level of prestress were taken as the study factors, and axial compression tests were conducted on each specimen to analyze their axial compression performance. The test results indicated that applying prestress to CFRP results in the core concrete being constantly subjected to triaxial compression, with initial transverse compressive strain and longitudinal tensile strain, thereby increasing the initial stiffness of the core concrete. In contrast to bonded CFRP-strengthened columns, the ultimate axial stress, ultimate axial strain, and initial stiffness of prestressed CFRP-strengthened columns increased with the level of CFRP prestress, with a more pronounced improvement observed in columns wrapped with a higher number of layers of CFRP. For a 4-layer CFRP strengthened column prestressed at 0.3, the ultimate axial stress and ultimate axial strain increased by up to 13 % and 20 %, respectively, compared to bonded 4-layer CFRP strengthened columns, with the initial stiffness increasing by up to 30 %. On the other hand, applying prestress to CFRP can significantly enhance the effective utilization of CFRP, but it is negatively correlated with the number of CFRP layers. Compared to bonded 1-layer CFRP strengthened columns, the effective utilization rate increased from 0.63 to 0.91, a 44 % increase, when prestressing CFRP at 0.3. Finally, based on existing relevant research, a peak stress and strain model considering the ratio of confinement stiffness to strain ratio was proposed. Based on the fundamental assumptions of curve analysis, the design-oriented axial stress-strain model suitable for prestressed CFRP strengthened concrete columns was established, with good match between theoretical and experimental curves.
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