Yeongchen-Si Agri-Technology CenterAbstract This study was conducted to investigate physiologically active components and antioxidant capacity ofgrapevine leaves at growth stages. The leaves from two strains of grapevine, ‘Campbell Early’ and ‘Rosario Bianco’, werecollected at five different growth stages (leafing, blossom, fruiting, coloring, and maturity). Total flavonoid content washigher in leafing stage than the other stages and gradually decreased during growing. Total phenol content was higher in‘Campbell Early’ than in ‘Rosario Bianco’. Hydroxyl radical scavenging ability increased in the leafing stage anddecreased during growing. The electron donating ability was higher in ‘Campbell Early’ then ‘Rosario Bianco’ untilblossom stage. Leaves from ‘Campbell Early’ showed higher total antioxidant capacity than those from ‘Rosario Bianco’.According to the above results, grapevine leaves until the blossom stage would possess strong antioxidant activity byphysiologically active components such as polyphenol compounds. Therefore, these results suggest that young grapevineleaves can be used as materials for the development of functional foods.Keywords: antioxidant activity, Campbell Early, Rosario Bianco, flavonoid, polyphenol