Regional business management methods, crisis management problems, recommendations received from internationally experienced partners, experience, and modern challenges are reviewed and supported by arguments in the article. The topic outlines the main strengths and weaknesses affecting the development of the region in general. Various critical assessments of opportunities and threats are identified. The article notes that regional business in our country has repeatedly found itself in a very difficult situation. The economic crisis, which has covered almost the entire economic segment, has become the subject of extraordinary research. As a result of the investigation of such a problem, a problem and strategy based on arguments should be developed. There is a need for a system of measures, which involves the support of today's Georgian business sector and the conditions adapted to them. The latter, by itself, will lead to the re-advance of the country. In general, one of the ways for the country to get out of the crisis is to strengthen the region as one of the main links of the economy. The paper talks about these problems. In particular, how it affects the economy, demography, and ways of solving problems. Based on all this, we should pay attention to strengthening the main, independent role of the region. These activities are very important. The business resources of the region are provided and the optimal tool for their management is created. This will further contribute to the efficiency and improvement of the quality of management, in conditions of a high level of promotion of regional business and provision of informational development. Natural raw material bases and the socioeconomic development of society are also important, as well as the optimization of relations between them. The development of existing methods, improvement of experience, development, and management information system will support and develop the development of new legal economic relations in the society, formation, and structural and fundamental transformation of the national economy. Keywords: small business, region, agriculture, state support.