During the summers of 1950 and 1951, the first author examined about 50 specimens of the Pacific giant salamander, Dicamptodon ensatus (Eschscholtz), collected near Portland, Oregon. About half of these were found to harbor a species of intestinal fluke with peculiar anatomical features. Although resembling trematodes assigned to the subfamilies PLEUROGENETINAE and CEPHALOGONIMINAE in some respects, this species could not be placed in any of their genera. The authors therefore propose for it the new genus Cephalouterina with Cephalouterina dicamptodoni n. sp. as type species. The specimens were fixed in either Bouin's fluid, formalin-alcohol-acetic or corrosive-acetic acid solution. They were stained with borax carmine or Ehrlich's hematoxylin, cleared in xylene or terpineol, and mounted in Clarite. Serial sections were stained with Galigher's alum hematoxylin and eosin. All measurements are in millimeters with averages in parentheses. We wish to express our thanks to Mr. Kenneth Neiland for his help in obtaining the salamanders utilized in this study and to Dr. R. M. Cable for critical reading of this paper.