Bone Gain Research Articles

Dimensional changes after horizontal and vertical guided bone regeneration without membrane fixation using the retentive flap technique: A 1-year retrospective study.

To evaluate the dimensional changes after horizontal and vertical guided bone regeneration (GBR) without membrane fixation using the retentive flap technique. This study retrospectively examined two cohorts that received vertical or horizontal ridge augmentations (VA or HA groups). GBR was performed using particulate bone substitutes and resorbable collagen membranes. The augmented sites were stabilized using the retentive flap technique without any additional membrane fixation. The augmented tissue dimensions were assessed using cone-beam computed tomography at preoperative, immediately postoperative (IP), 4 months (4M), and 1 year (1Y). Postoperative vertical bone gain in 11 participants of VA group amounted to 5.96 ± 1.88 mm at IP, which decreased to 5.53 ± 1.62 at 4M and to 5.26 ± 1.52 mm at 1Y (intragroup p < 0.05). The horizontal bone gain at IP in 12 participants amounted to 3.98 ± 2.06 mm, which decreased to 3.02 ± 2.06 at 4M and to 2.48 ± 2.09 mm at 1Y (intragroup p < 0.05). The mean implant dehiscence defect height after 1Y was 0.19 ± 0.50 mm in the VA group, and 0.57 ± 0.93 mm in the HA group. GBR without membrane fixation using the retentive flap technique seems to preserve the radiographic bone dimensions of vertically augmented sites. This technique may be less effective at preserving the width of the augmented tissue.

Effectiveness and complications of transcrestal sinus floor elevation using the cushioned grind-out technique: A retrospective cohort study with up to 7 years of follow-up.

To evaluate the effectiveness and complications of the cushioned grind-out technique. The primary outcome was endo-sinus bone gain (ESBG), while secondary outcomes included the Schneiderian membrane perforation rate and mid- to long-term implant survival. In this retrospective study, we compared the cushioned grind-out technique with the classic osteotome technique, establishing statistical models to assess ESBG, membrane perforation rate and implant survival rate. A total of 259 patients and 340 implants were included. The mean ESBG was 5.31 mm for the cushioned grind-out group and 4.64 mm for the osteotome group. Multivariable regression analysis revealed that the cushioned grind-out technique significantly facilitated ESBG (p = .028). Nineteen preparation sites experienced membrane perforation, with rates of 5.5% and 6.4% for the cushioned grind-out and osteotome groups, respectively. However, the difference was not statistically significant (p = .920). Additionally, the cumulative survival rate of the implants for 7 years was 95.2% and 91.4%, respectively, with the surgical technique not significantly influencing the results. With 6 months to 7 years of post-prosthetic restoration review data, our findings show that the cushioned grind-out technique facilitates a higher ESBG, with no significant difference in membrane perforation or implant failure rate.

A New Concept of Horizontal Bone Augmentation Using Collagen Bovine Bone Blocks Without Membrane at Implant Placement: A Preliminary Study.

A buccal bone thickness (BBT) of at least 1.8-2mm is necessary to ensure long-term implant stability, and a bone grafting procedure is commonly needed to restore this BBT. This study aims to prove the effectiveness of a novel bone augmentation technique in which minero-organic bone substitutes are solely used to restore adequate BBT, excluding the need for coverage membranes. Fifty partially edentulous patients having a residual bone width ranging between 5 and 6mm were enrolled in this study. The horizontal buccal defects were grafted simultaneously at implant placement. Minero-organic collagen bovine bone blocks (CBBB) were placed on the outer side of the buccal bone wall, and adapted to the defect morphology through slow compressive movements. The grafted sites were not covered with any type of membrane nor stabilized with fixation pins. Cone-beam computed tomography scans were obtained pre-operatively, immediately post-surgery, and four months later. Scans were superimposed on the ITK-Snap software to measure the amount of bone gain and assess the percentage of CBBB resorption. Measurements were effectuated at four different levels apically to crestal level. Radiographic findings showed BBT increase and CBBB resorption in all cases, four months post-grafting. A mean horizontal bone gain of 1.39mm was calculated at a crestal level. Based on these findings, it appears that this novel and user-friendly bone grafting technique can achieve positive outcomes from both clinical and radiographic perspectives.

Effect of Different Crestal Sinus Lift Techniques for Implant Placement in the Posterior Maxilla of Deficient Height: A Randomized Clinical Trial

This study evaluated dental implant stability, vertical bone gain, bone density, and crestal bone loss using different crestal sinus lift techniques (osteotomy, Densah burs, and piezosurgery). A total of 21 patients were randomly divided into three groups: Group 1: patients were treated using a Densah drill crestal sinus lift, Group 2: patients were treated using a piezoelectric crestal sinus lift and Group 3: patients were treated using an osteotome crestal sinus lift. The patients in all three groups underwent bone grafting and implant placement. An Osstell device was used to determine the implant stability by recording the values of the implant stability quotient (ISQ). CBCT was performed before and 6 months after implant placement for radiographic evaluation and comparison among the groups. All dental implants were completely successful, and statistically significant differences from baseline to 6 months were noted in all groups (p &lt; 0.05). The Densah burs technique resulted in the best implant stability of all groups, while the osteotome technique demonstrated better vertical bone augmentation. However, the values for bone density and crestal bone loss showed no significant difference among all treated groups (p &gt; 0.05). All three techniques were successful for crestal sinus lifts with good clinical outcomes at a 6-month follow-up. The Densah group demonstrated better implant stability, shorter surgery time, and fewer complications; however, the vertical bone gain was greater with the osteotome technique.

Endoscope-assisted maxillary sinus floor augmentation with a mini-lateral window: A retrospective study.

The aim of this study was to evaluate the efficacy of endoscope-controlled sinus floor augmentation through a mini-lateral window, compared with traditional lateral window approach. This retrospective research included 19 patients and 20 augmented sinuses using lateral window approach with simultaneous implant placement (test group: a 3-4 mm round osteotomy; control group: a 10 × 8 mm rectangular osteotomy). Preoperatively (T0), immediately after surgery (T1), and 6 months postoperatively (T2), cone-beam computed tomography (CBCT) scans were obtained. Residual bone height (RBH), lateral window dimension (LWD), endo-sinus bone gain (ESBG), apical bone height (ABH), and bone density were measured. Intraoperative and postoperative complications were recorded. Patients' evaluation of pain first day after surgery and a week later was assessed by visual analog scale (VAS). No significant difference was found in ESBG, ABH between the two groups at T1, T2 or their changes from T1 to T2. However, the increase of bone density value in the test group was significantly higher than control group (356.28 ± 149.59 vs. 242.99 ± 129.54; p < 0.05). The sinus perforation rate of test and control group was 10% and 20%, respectively. The VAS score of the test group at the first day after surgery was significantly lower than control group (4.20 ± 1.03 vs. 5.60 ± 1.71; p < 0.05). Endoscope-controlled maxillary sinus floor augmentation through a mini-lateral window yield similar result with traditional approach in terms of bone height gain. The modified approach could facilitate new bone formation, reducing sinus perforation rate and postoperative pain.

Incidence of Peri-Implantitis, Technical and Biological Complications of Single Implants Placed with Flap or Flapless Surgery-A 10-12-Year Case-Series.

Long-term follow-up of single implants and crowns is scarce, especially when inserted using flapless surgery. Evaluate survival, peri-implantitis incidence, and technical/biologic complications of solitary implants/crowns after 10-12 years of function. 49 patients with 53 single implants, initially operated with a one-stage flap (F) or flapless (FL) surgery and delayed loading, were recalled. Implant survival, radiographic bone-level changes compared to baseline, peri-implant health, and soft tissue aesthetics were registered. Differences in implant level between and within groups were statistically tested using the Mann-Whitney U-Test and Wilcoxon Signed Ranks Test, respectively. 36 patients with 40 implants were reassessed, yielding 100% implant and 97.5% crown survival. The bone loss in F (n = 19) was 0.56 mm (SD 0.89; range -0.9-2.02) and -0.85 mm (SD 0.98; range -2.84-0.53) in FL (n = 21), indicative of bone gain in FL (p = 0.003), the latter due to a difference at baseline but bone-level was comparable (p = 0.126). Groups were comparable for probing pocket depth (PPD); (3.32 vs. 3.19 mm), Bleeding Index (BI); (0.15 vs. 0.22), and gingival recession; (0.38 vs. 0.17 mm). According to international criteria, the peri-implantitis incidence was 0%, but 32.5% of the implants/crowns experienced biological or technical complications irrespective of surgical technique. Solitary implants and crowns show good long-term clinical outcomes and peri-implant health. Flapless surgery is a good alternative to conventional in straightforward cases with sufficient bone volume and proper treatment planning.

Cushioned grind-out technique transcrestal sinus floor elevation for simultaneous implantation in severe atrophic maxilla: A retrospective study with up to 7 years of follow-up.

This study aimed to evaluate the effects of the cushioned grind-out technique transcrestal sinus floor elevation for simultaneous implant placement with ≤4 mm of residual bone height (RBH). This was a retrospective propensity score matching (PSM) study. Five PSM analyses included the confounding variables of Schneiderian membrane perforation, early and late implant failure, and peri-implant apical and marginal bone resorption. After PSM, we compared the difference in five aspects between the RBH ≤ 4 and >4 mm groups. A total of 214 patients with 306 implants were included in this study. After PSM, the generalized linear mixed model (GLMM) indicated that RBH ≤ 4 mm had no significantly higher risk of Schneiderian membrane perforation and early and late implant failure (p = .897, p = .140, p = .991, respectively). The implant cumulative 7-year survival rate of the RBH ≤ 4 and >4 mm groups was 95.5% and 93.9%, respectively (log-rank test: p = .900). Within at least 40 cases per group after PSM, two multivariate GLMMs indicated that RBH ≤ 4 mm could not be identified as the promotive factor of bone resorption of either endo-sinus bone gain or crest bone level (RBH × time interaction p = .850, p = .698, respectively). Within the limitations, 3 months to 7 years of post-prosthetic restoration review data indicated an acceptable mid-term survival and success rate of applying the cushioned grind-out technique in RBH ≤ 4 mm cases.

Quantifizierung von biomechanischen und morphologischen Eigenschaften der Patellarsehne mittels Myotonometrie und Panaroma-Ultraschalldiagnostik – eine Reliabilitätsstudie

The purpose of this study was to characterize arthroscopically the frequency and location of the glenoid bare area.Three fellowship-trained orthopaedic sports surgeons evaluated and characterized the bare area of the glenoid in 52 consecutive patients undergoing arthroscopic surgery of the shoulder without a diagnosis of instability. Among the patients with a visible bare area, the position was measured, and when eccentrically located, an apparent bone loss or gain was calculated.The bare area of the glenoid was observed in only 48% of patients undergoing arthroscopic surgery, and when observed, it was at the center only 37% of the time. Of the glenoids with visible bare areas, 8% were located anteriorly enough to result in an apparent bone loss calculation of greater than 20%. An additional 25% of visible bare areas were posteriorly located, resulting in an apparent bone gain.The glenoid bare area is a variably visible and eccentric landmark on the glenoid and thus should not be used as the sole reference point to measure glenoid bone loss.Level IV, retrospective observational study.

Vergleich der isometrischen Maximalkraft der Hüftgelenksabduktoren und Kniegelenksextensoren zwischen Kniearthrose-Patienten mit und ohne Instabilitätsgefühl

The purpose of this study was to characterize arthroscopically the frequency and location of the glenoid bare area.Three fellowship-trained orthopaedic sports surgeons evaluated and characterized the bare area of the glenoid in 52 consecutive patients undergoing arthroscopic surgery of the shoulder without a diagnosis of instability. Among the patients with a visible bare area, the position was measured, and when eccentrically located, an apparent bone loss or gain was calculated.The bare area of the glenoid was observed in only 48% of patients undergoing arthroscopic surgery, and when observed, it was at the center only 37% of the time. Of the glenoids with visible bare areas, 8% were located anteriorly enough to result in an apparent bone loss calculation of greater than 20%. An additional 25% of visible bare areas were posteriorly located, resulting in an apparent bone gain.The glenoid bare area is a variably visible and eccentric landmark on the glenoid and thus should not be used as the sole reference point to measure glenoid bone loss.Level IV, retrospective observational study.

Return-to-Play: Bedeutung der Kraftentwicklung drei und sechs Monate nach VKB-Rekonstruktion

The purpose of this study was to characterize arthroscopically the frequency and location of the glenoid bare area.Three fellowship-trained orthopaedic sports surgeons evaluated and characterized the bare area of the glenoid in 52 consecutive patients undergoing arthroscopic surgery of the shoulder without a diagnosis of instability. Among the patients with a visible bare area, the position was measured, and when eccentrically located, an apparent bone loss or gain was calculated.The bare area of the glenoid was observed in only 48% of patients undergoing arthroscopic surgery, and when observed, it was at the center only 37% of the time. Of the glenoids with visible bare areas, 8% were located anteriorly enough to result in an apparent bone loss calculation of greater than 20%. An additional 25% of visible bare areas were posteriorly located, resulting in an apparent bone gain.The glenoid bare area is a variably visible and eccentric landmark on the glenoid and thus should not be used as the sole reference point to measure glenoid bone loss.Level IV, retrospective observational study.

Rückkehr zum Sport nach Rekonstruktion des vorderen Kreuzbandes - Welche Faktoren beeinflussen die Return to Sport-Entscheidung?

The purpose of this study was to characterize arthroscopically the frequency and location of the glenoid bare area.Three fellowship-trained orthopaedic sports surgeons evaluated and characterized the bare area of the glenoid in 52 consecutive patients undergoing arthroscopic surgery of the shoulder without a diagnosis of instability. Among the patients with a visible bare area, the position was measured, and when eccentrically located, an apparent bone loss or gain was calculated.The bare area of the glenoid was observed in only 48% of patients undergoing arthroscopic surgery, and when observed, it was at the center only 37% of the time. Of the glenoids with visible bare areas, 8% were located anteriorly enough to result in an apparent bone loss calculation of greater than 20%. An additional 25% of visible bare areas were posteriorly located, resulting in an apparent bone gain.The glenoid bare area is a variably visible and eccentric landmark on the glenoid and thus should not be used as the sole reference point to measure glenoid bone loss.Level IV, retrospective observational study.

Erfolgreiche Refixierung von traumatischen, reinen Knorpelfragmenten im kindlichen und jugendlichen Knie

The purpose of this study was to characterize arthroscopically the frequency and location of the glenoid bare area.Three fellowship-trained orthopaedic sports surgeons evaluated and characterized the bare area of the glenoid in 52 consecutive patients undergoing arthroscopic surgery of the shoulder without a diagnosis of instability. Among the patients with a visible bare area, the position was measured, and when eccentrically located, an apparent bone loss or gain was calculated.The bare area of the glenoid was observed in only 48% of patients undergoing arthroscopic surgery, and when observed, it was at the center only 37% of the time. Of the glenoids with visible bare areas, 8% were located anteriorly enough to result in an apparent bone loss calculation of greater than 20%. An additional 25% of visible bare areas were posteriorly located, resulting in an apparent bone gain.The glenoid bare area is a variably visible and eccentric landmark on the glenoid and thus should not be used as the sole reference point to measure glenoid bone loss.Level IV, retrospective observational study.

Einfluss perkussiver Massage auf den Muskeldehnungsreflex bei plötzlicher Supination des Fußes

The purpose of this study was to characterize arthroscopically the frequency and location of the glenoid bare area.Three fellowship-trained orthopaedic sports surgeons evaluated and characterized the bare area of the glenoid in 52 consecutive patients undergoing arthroscopic surgery of the shoulder without a diagnosis of instability. Among the patients with a visible bare area, the position was measured, and when eccentrically located, an apparent bone loss or gain was calculated.The bare area of the glenoid was observed in only 48% of patients undergoing arthroscopic surgery, and when observed, it was at the center only 37% of the time. Of the glenoids with visible bare areas, 8% were located anteriorly enough to result in an apparent bone loss calculation of greater than 20%. An additional 25% of visible bare areas were posteriorly located, resulting in an apparent bone gain.The glenoid bare area is a variably visible and eccentric landmark on the glenoid and thus should not be used as the sole reference point to measure glenoid bone loss.Level IV, retrospective observational study.

Vergleichbare Knie-Biomechanik aber unterschiedliche Muskelaktivierung nach VKB-Naht mit InternalBraceTM-Verstärkung und VKB-Rekonstruktion

The purpose of this study was to characterize arthroscopically the frequency and location of the glenoid bare area.Three fellowship-trained orthopaedic sports surgeons evaluated and characterized the bare area of the glenoid in 52 consecutive patients undergoing arthroscopic surgery of the shoulder without a diagnosis of instability. Among the patients with a visible bare area, the position was measured, and when eccentrically located, an apparent bone loss or gain was calculated.The bare area of the glenoid was observed in only 48% of patients undergoing arthroscopic surgery, and when observed, it was at the center only 37% of the time. Of the glenoids with visible bare areas, 8% were located anteriorly enough to result in an apparent bone loss calculation of greater than 20%. An additional 25% of visible bare areas were posteriorly located, resulting in an apparent bone gain.The glenoid bare area is a variably visible and eccentric landmark on the glenoid and thus should not be used as the sole reference point to measure glenoid bone loss.Level IV, retrospective observational study.

The posterior cruciate ligament–posterior femoral cortex angle: A reliable and accurate MRI method to quantify the buckling phenomenon of the PCL in ACL‐deficient knees

The purpose of this study was to characterize arthroscopically the frequency and location of the glenoid bare area.Three fellowship-trained orthopaedic sports surgeons evaluated and characterized the bare area of the glenoid in 52 consecutive patients undergoing arthroscopic surgery of the shoulder without a diagnosis of instability. Among the patients with a visible bare area, the position was measured, and when eccentrically located, an apparent bone loss or gain was calculated.The bare area of the glenoid was observed in only 48% of patients undergoing arthroscopic surgery, and when observed, it was at the center only 37% of the time. Of the glenoids with visible bare areas, 8% were located anteriorly enough to result in an apparent bone loss calculation of greater than 20%. An additional 25% of visible bare areas were posteriorly located, resulting in an apparent bone gain.The glenoid bare area is a variably visible and eccentric landmark on the glenoid and thus should not be used as the sole reference point to measure glenoid bone loss.Level IV, retrospective observational study.

Unterschiede der isokinetischen Muskelfunktionsanalyse und dynamischen Sprungtestung einer Frauenamateurfußballmannschaft im Vergleich zu einer Frauenprofifußballmannschaft

The purpose of this study was to characterize arthroscopically the frequency and location of the glenoid bare area.Three fellowship-trained orthopaedic sports surgeons evaluated and characterized the bare area of the glenoid in 52 consecutive patients undergoing arthroscopic surgery of the shoulder without a diagnosis of instability. Among the patients with a visible bare area, the position was measured, and when eccentrically located, an apparent bone loss or gain was calculated.The bare area of the glenoid was observed in only 48% of patients undergoing arthroscopic surgery, and when observed, it was at the center only 37% of the time. Of the glenoids with visible bare areas, 8% were located anteriorly enough to result in an apparent bone loss calculation of greater than 20%. An additional 25% of visible bare areas were posteriorly located, resulting in an apparent bone gain.The glenoid bare area is a variably visible and eccentric landmark on the glenoid and thus should not be used as the sole reference point to measure glenoid bone loss.Level IV, retrospective observational study.

Zerkleinerung des Knorpels mittels Shavers reduziert die Viabilität von bovinen Knorpelzellen unabhängig von Shavergröße

The purpose of this study was to characterize arthroscopically the frequency and location of the glenoid bare area.Three fellowship-trained orthopaedic sports surgeons evaluated and characterized the bare area of the glenoid in 52 consecutive patients undergoing arthroscopic surgery of the shoulder without a diagnosis of instability. Among the patients with a visible bare area, the position was measured, and when eccentrically located, an apparent bone loss or gain was calculated.The bare area of the glenoid was observed in only 48% of patients undergoing arthroscopic surgery, and when observed, it was at the center only 37% of the time. Of the glenoids with visible bare areas, 8% were located anteriorly enough to result in an apparent bone loss calculation of greater than 20%. An additional 25% of visible bare areas were posteriorly located, resulting in an apparent bone gain.The glenoid bare area is a variably visible and eccentric landmark on the glenoid and thus should not be used as the sole reference point to measure glenoid bone loss.Level IV, retrospective observational study.

Clinical and Radiological Benefits of Hyaluronic Acid in Periodontal Infrabony Defects: A Systematic Review and Meta-analysis

Purpose: There is no consensus on the clinical and radiological benefits of hyaluronic acid (HA) in patients with periodontitis having infrabony defects. Hence, this study examined the effects of HA in periodontitis patients with infrabony defects through a comprehensive systematic review process. Methodology: A systematic literature search was performed using PubMed/Medline, Scopus, Embase and Cochrane Library from inception to March 2022. Randomized or non-randomized clinical trials and single-arm clinical trials that assessed the clinical and radiological benefits of HA in periodontitis patients with infrabony defects with a minimum of 6 months follow-up were included in this study. Surgical regenerative therapy was considered as the comparator. The Cochrane risk of bias assessment tool and Downs and Black checklist was used for the quality assessment of randomized and non-randomized interventional studies, respectively. A subgroup and sensitivity analyses were performed to explore the heterogeneity and robustness of the findings, respectively. Results: A total of 13 out of 725 studies were included in this systematic review, of which 9 were considered for meta-analysis. The meta-analysis indicated significant benefits of HA in terms of reduction in probing pocket depth (SMD: 1.12mm; 95%CI: 0.60-1.65; 9 studies), bone defect depth (SMD: 1.04mm; 95%CI: 0.62-1.47; 3 studies) and gain in clinical attachment level (SMD: 1.40 mm; 95%CI: 0.33-2.47; 8 studies). Overall, the quality of included studies was good. Conclusion: The current evidence indicates that the administration of HA in the periodontal regenerative treatment of infrabony defects was significantly effective in increasing clinical attachment levels and reducing probing pocket and bone defect depth.

Fiber-reinforced composite full-arch prosthetic reconstructions supported by three standard, short or extra-short implants: a two-center retrospective study.

To evaluate the survival of implants and prostheses, and marginal bone level of fiber-reinforced composite implant supported fixed complete prostheses supported by 3 implants. Patients with fiber-reinforced composite fixed prostheses supported by 3 standard-length, short or extra-short implants were included in this retrospective cohort study. Kaplan-Meier survival was computed for implants and prostheses. Univariate and multivariate Cox proportional hazard regressions, clustered by patient, were used to analyze bone level differences as a function of different study covariates. Linear regressions were used to investigate the relationship between distal extension lengths and bone levels. Forty-five patients with 138 implants were followed for up to 10years after prosthesis insertion (mean 52.8; SD 20.5months). Kaplan-Meier survival analysis showed overall survival rates of 96.5% for implants and of 97.8% for prostheses. The 10-year success rate for prostheses was 90.8%. Extra-short implants survived at similar rates to short and standard implants. Marginal bone levels surrounding implants remained stable over time, even showing slight bone gain on average (mean + 0.1mm/year; SD ± 0.5mm/year) Acrylic denture teeth, overdentures on the opposing arch, and implant placement in the posterior maxilla were correlated with bone gain. Screw retention, opposed to telescopic retention, was correlated with bone loss. Longer distal extensions were correlated with bone gain on the implants closest to the distal extensions. Fiber-reinforced composite fixed prostheses supported by only 3 implants, most of which were extra-short, presented high survival rates with stable bone levels. An encouraging prognosis can be expected for restoration of atrophic maxillary and mandibular arches, when restored with fixed fiber-reinforced composite frameworks with long distal extensions and supported on only 3 short implants.

Comparison between Platelet-rich Fibrin and Saline Filling after Sinus Elevation without Adjunctive Bone Graft in Dental Implants Insertion Using CBCT.

The goal of this research was to compare radiographically the outcomes of hydraulic transcrestal sinus lifting with platelet-rich fibrin (PRF) or normal saline filling on implant survival rates, negative outcomes, and variations in the height of residual alveolar ridge (HARB). There were 80 study participants included and 90 dental implants were placed. The study participants were divided into two categories: Category A and Category B. Each category consists of 40 study participants. Category A: Normal saline was placed in the maxillary sinus. Category B: PRF was placed in the maxillary sinus. Implant survival, complications, and HARB alterations were the outcome metrics. Radiographic images through Cone-beam computed tomography (CBCT) were retrieved and compared prior to surgery (T0), immediately following surgery (T1), three months later (T2), 6 months later (T3), and 12 months later (T4). There are 90 implants having an average length of 10.5 ± 0.7 mm were inserted into the posterior portion of the maxilla of 80 patients with an average HARB of 6.9 ± 1.2 mm. At T1, elevation in HARB peaked, and the sinus membrane continued to droop but steadied while observed at T3. The steady increment of areas of radiopacities was noticed below the elevated membrane of the maxillary antrum. A radiographic intrasinus bone increase of 2.9 ± 1.4 mm was caused by the PRF filling, compared to 1.8 ± 1.1 mm by the saline filling at T4 (p < 0.05). Over the course of the one-year follow-up period, all of the implants were operating normally with no major issues. Platelet-rich fibrin when used as a filling medium alone without bone graft can cause significant ascend in height of the residual alveolar bone (HRAB). The degradation of the alveolar bone under the maxillary sinus following tooth loss frequently restricts the placement of the implant in the edentulous region of posterior maxilla. Numerous sinus-lifting surgery procedures and tools have been developed to address these problems. It has been a topic of debate regarding the benefits of bone grafts placed at the apical region of the implant. The sharp protrusions of the granules of bone graft may also provide a danger of membrane puncture. Recently, it was shown that regular bone gain might occur inside the maxillary antrum without the use of any bone transplant material. Additionally, if there were substances that filled the gap between the floor of the sinus and the raised sinus membrane, then the membrane of the maxillary sinus could be raised greater and for a longer period of time during the phase of formation of new bone formation.