Smoking in adolescents has become a habit and the proportion tends to increase. The cause of teenagers smoking psychologically was for relaxation, giving calm and coping with stress. The purpose of this study was to examine the influence of stress management on adolescent smoking behavior in West Bogor District Vocational High School (SMK). The results of this study are expected to be useful for the preparation and implementation of intervention programs and as a guide for nurses in providing stress management interventions. The research design was Quasi-Experimental using pre and post tests with Control Group. Before the selection of respondents, screening was conducted on 5 SMKs totaling 410 students. From the results of the screening, it was found that the number of adolescents who smoked less than or equal to5 cigarettes per day with mild and moderate stress levels was 108 students. This group was divided into two, namely the control group 54 students and the intervention group 54 students. The results showed that the average number of cigarettes smoked per day in the intervention group decreased from 3.30 to 1.42 cigarettes. There was a significant decrease in smoking behavior in adolescents after getting stress management interventions (P value 0,000).