Distribution Of Blood Groups Research Articles

Study the Relationship between Asthma Severity and ABO Blood Group Phenotype in Sample of Iraqi patients with Chronic Bronchial Asthma

Purpose: To find ABO blood group distribution among asthmatic patients in addition to the association between blood group phenotype and asthma severity. Methods: Sixty patients with asthma were included in this study. The ABO and Rh blood group were determined using agglutination reaction method. Asthma control test (ACT) and pulmonary function test (PFT) using spirometry were used for determination of asthma severity. Results: The blood group distribution among asthmatic patients was in order of B>A>O>AB with the frequency distribution of (33.33%), (30%), (28.33%), (8.34%) respectively with significant differences among them (P<0.05) and (90%) of patients was with Rh blood group positive. Regarding asthma control test (ACT) most of asthmatic patients (78.3%) presented with uncontrolled asthma, (25%) was with blood group (O) followed by blood group (A, B) in same frequency (23.3%). Pulmonary function test using Spirometry, the forced expiratory volume in one second (FEV1), it was found that (71.7%) of asthmatic patients had severe asthma (FEV1<60) mostly in patients with blood group A (23.4%) and O (21.7%). Severe asthma in case of Forced Vital Capacity (FVC<60) mostly found in patients with blood group O (20%). Blood group B (26.7%) is associated with severe asthma in case of peak expiratory flow (PEF<60). Conclusion: Although this study tries to find association between ABO blood group phenotype distribution and asthma prevalence, there is no unanimity in this finding regarding the association of ABO blood group phenotype and asthma severity.

Türkiye'nin Karmaşık Etnik Kökenini Temsil Eden İstanbul’da ABO ve Rh (D) Gruplarının Dağılımı

Objective: In humans, 38 different critical blood type classification systems are currently recognized. They differ in frequencies in distinct populations. It is aimed to visualize ABO and Rh(D) groups distribution in Istanbul as having the largest community in Turkey. Method: Volunteered blood donor's data on the automation system were screened retrospectively. Blood donation acceptance criteria were based on the guidelines prepared by the Ministry of Health. ABO and Rh(D) groups were analyzed using column agglutination/gel centrifugation methods. Results: The study covered six years' data between the dates of January 2014 and December 2019, including 136,231 donors. The majority of the donors were found to have blood group A with a frequency of 41.88%(n=57,059). The second most common blood group was group O, and had a frequency of 34.92%(n=47,576). The blood group B (n=20,790;15.26%) and group AB (n=10,806;7.93%) were found to be the rare encountered blood groups. Among the Rh(D) group, 85.02% of the donors were Rh(D) positive. Conclusion: In transfusion medicine, ABO and Rh(D) groups' compatibility is mandatory. According to the monthly and or annual blood products requirement, there are some suggested quantities of blood units to be available at blood centres. Determining the frequency of blood group distribution of populations will help to coordinate the ratio of blood groups to be storaged. The Turkish genetic makeup is a fascinating mixture of European and Asian DNA, necessitates to find out the countries' specific ABO and Rh(D) groups ratio. We compared our results with the previously reported studies performed in different cities of Turkey and the world around. Thus, our research as giving the overall distribution of ABO and Rh(D) groups from the largest city of Turkey reflecting the general ethnic background of the country, would help to the establishment of a databank of ABO and Rh(D) group's ratio.

Donor profile and prevalence of transfusion transmitted diseases among voluntary blood donors

Knowing about ABO and Rh blood group distribution among voluntary donors is important as it helps in better management of blood bank inventory. Current study was done to know the distribution of ABO, Rh blood groups and also the seroprevalance of transfusion transmitted infections in donors attending voluntary blood donation camps. This an observational cross sectional study conducted over a period of six months at a blood bank attached to a private medical college. There were 378 voluntary blood donors during this study period. Male donors constituted 87.6% (268) and females 12.4% (37). Predominant blood group was O positive 146 (38.6%), followed by B positive 110 (29.1%).

Investigation on compliance with sepsis bundle and outcomes in patients with septic shock in Changshu area

Objective: To perform a statistical analysis of the ABO blood group distribution of COVID-19 convalescents, and further analyze the ABO blood group distribution in COVID-l9 convalescents with different plasma antibody titer against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-Z).

Association of ABO blood group with crowding among patients with different malocclusions

Introduction: This study correlated ABO blood groups and crowding in the lower anterior region and also to find an interrelationship between ABO blood grouping system and sagittal relation of the jaws. Materials and Methods: The sample size consisted of 138 Maharashtrian patients (60 males and 78 females) age range from 12 to 30 years which were randomly selected. Each patient's records comprised: a lateral cephalometric head film, photographs, and dental casts as standard pretreatment records. Based on ANB angles, patients were divided into Group-1: ANB 1–3° (51 individuals with 27 males and 24 females), Group-2: ANB >3° (60 individuals with 24 males and 36 females), and Group-3: ANB Results: The mean ± standard deviation of age in Group 1, Group 2, and Group 3 was 16.53 ± 2.43 years, 17.60 ± 3.73 years, and 18.67 ± 3.28 years, respectively. The gender distribution of cases studied did not differ significantly across three study groups. The distribution of median ANB did not differ significantly across various blood groups in the study group. The blood group distribution of cases studied did not differ significantly across three study groups. The distribution of Little's index differs significantly across perfect alignment and minimal irregularity as well as between minimal irregularity and moderate irregularity. The distribution of Little's index did not differ significantly between perfect alignment and moderate irregularity. Conclusions: The occurrence of blood group B+ was more in Class I and II skeletal patterns whereas in Class III skeletal pattern individuals have more prevalence of blood group A+. ABO blood groups and Little's Irregularity Index for crowding is found to be correlated between perfect alignment and minimal irregularity individuals as well as between minimal and moderate irregularity subjects.

Retrospective analysis of clinical features in 134 coronavirus disease 2019 cases.

We aimed to describe the clinical features in coronavirus disease 2019 (COVID-19) cases. We studied 134 critically ill COVID-19 cases from 30 December 2019 to 20 February 2020 in an intensive care unit (ICU) at Wuhan Jinyintan Hospital. Demographics, underlying diseases, therapy strategies and test results were collected and analysed from patients on admission, admission to the ICU and 48 h before death. The non-survivors were older (65.46 (s.d. 9.74) vs. 46.45 (s.d. 11.09)) and were more likely to have underlying diseases. The blood group distribution of the COVID-19 cases differed from that of the Han population in Wuhan, with type A being 43.85%; type B, 26.92%; type AB, 10% and type O, 19.23%. Non-survivors tend to develop more severe lymphopaenia, with higher C-reactive protein, interleukin-6, procalcitonin, D-dimer levels and gradually increased with time. The clinical manifestations were non-specific. Compared with survivors, non-survivors more likely to have organ function injury, and to receive mechanical ventilation, either invasively or noninvasively. Multiple organ failure and secondary bacterial infection in the later period is worthy of attention.

ABO and Rh Blood Groups and Risk of Myelomeningocele.

To investigate the relationship between the distribution of ABO or Rhesus (Rh) blood group antigens and the incidence of myelomeningocele. A retrospective data was reviewed for all myelomeningocele patients operated at a tertiary academic hospital between years 2014 and 2019. Age, sex, delivery method, physical and neurological examination findings, and radiological findings alongside with blood type of each patient were recorded. The data of blood group distribution among the study patients was compared to the data of healthy individuals in the same region. Patients with group B and AB showed a higher chance of developing myelomeningocele. Rh-positive blood group was associated with high incidence of myelomeningocele (93.5%), whereas Rh-negative blood group showed least association (6.5%). Rh-positive blood group was also found to be more frequent in patients with myelomeningocele with hydrocephalus and Chiari malformation. The findings of this study show that ABO and Rh blood groups have an effect on the development of myelomeningocele under the influence of environmental or genetic factors.

ABO blood groups and hepatitis B virus infection: a systematic review and meta-analysis

ObjectiveHepatitis B virus (HBV) infection is a major public health problem worldwide. Several studies have reported that ABO blood groups may be associated with HBV infection. However, its association is...

Association of Fingerprints with the ABO Blood grouping among students in Gandaki Medical College

Introduction: Dermatoglyphic study is undoubtedly the most reliable, convenient and acceptable method of individual identification since the fingerprint pattern persist same throughout the life and no two individ­ual has similar pattern. Both blood group and dermatoglyphic pattern have genetic inheritance so an attempt has been made to analyze their correlation with gender and blood group of an individual.&#x0D; Methods: A cross sectional study was carried out in 200 students (105 male and 95 female), aged 17to 27 years, with prior knowledge of their blood group, of Gandaki Medical College, Pokhara, Nepal. The finger­print patterns of both hands were recorded and patterns were observed.&#x0D; Results: Loop was the most common pattern registering 51.8% followed by whorls, arches and composite in both genders. Frequency of loop was higher in both male and female. Frequency of whorl was comparative­ly higher in male (41.3%) compared to female (38.8%). Similarly arch was more common in female (9.89%) than in male (5.05%).Frequency of loop was highest in all blood groups in both male and female; followed by whorls, arches and composite. Both loops and whorls were highest in individual with O+ blood group. Arch was found to be highest in B+ subjects.&#x0D; Conclusion: There was no significant association between distribution of fingerprint patterns, blood group and gender and thus prediction of gender and blood group of a person is not possible based on his finger­print pattern.

Blood Groups and their Association with Academic Performance among Medical Students in a Nepalese Medical College

Introduction: Knowing a person’s blood type is not only important in transfusion medicine and forensic medicine but is also useful for predicting a person’s characteristics including intelligence, knowledge, skill and behavior. It is recognized that intelligence, knowledge and skill are assessed by performance in examination. The objective of this study was to determine distribution of blood groups among students and its association with their academic performance. Methods: This was an analytical study that was conducted among the medical students of Nepalese Army Institutes of Health Sciences (NAIHS) in Department of Clinical Physiology from June 2014 to April 2019. This study was conducted among 738 students by using convenient sampling method. Blood group was determine on the basis of agglutination reaction. Academic performance of students was assessed by the marks obtained by them in annual final examination. Results: Blood group O was the most prevalent at 33.5%, followed by B at 29.5%, A at 29% and AB at 8%. Distribution of Rh positive and Rh negative were 96.6% and 3.4% respectively. The mean scores obtained in final university examination were highest in blood group A (62.9%) and lowest in blood group AB (60.3%) but the difference between different blood groups was not statistically significant. Conclusion: Blood group O was the most common blood group. Rh positive was present in 96.6%. Though mean score was highest in blood group A, significant association between blood groups and academic performance was not seen in our study.

Blood Groups and their Association with Academic Performance among Medical Students in a Nepalese Medical College

Introduction Knowing a person’s blood type is not only important in transfusion medicine and forensic medicine but is also useful for predicting a person’s characteristics including intelligence, knowledge, skill and behavior. It is recognized that intelligence, knowledge and skill are assessed by performance in examination. The objective of this study was to determine distribution of blood groups among students and its association with their academic performance.&#x0D; MethodsThis was an analytical study that was conducted among the medical students of Nepalese Army Institutes of Health Sciences (NAIHS) in Department of Clinical Physiology from June 2014 to April 2019. This study was conducted among 738 students by using convenient sampling method. Blood group was determined on the basis of agglutination reaction. Academic performance of students was assessed by the marks obtained by them in annual final examination.&#x0D; ResultsBlood group O was the most prevalent at 33.5%, followed by B at 29.5%, A at 29% and AB at 8%. Distribution of Rh positive and Rh negative were 96.6% and 3.4% respectively. The mean scores obtained in final university examination were highest in blood group A (62.9%) and lowest in blood group AB (60.3%) but the difference between different blood groups was not statistically significant.&#x0D; ConclusionBlood group O was the most common blood group. Rh positive was present in 96.6%. Though mean score was highest in blood group A, significant association between blood groups and academic performance was not seen in our study.

Association of Consanguinity and ABO Blood Groups with β-thalassemia major in District Dadu and Hyderabad, Pakistan

Consanguineous marriages are the deeply rooted social trend in Pakistan, which lead to the high prevalence of inherited diseases. Thalassemia is an inherited disorder characterized by the abnormal synthesis of hemoglobin leading to anemia. β-thalassemia is the most common inherited disorder in Pakistan particularly in Sindh. The patients of β-thalassemia need repeated transfusion, which might cause complications causing the high rate of mortality in blood transfusion dependent β-thalassemia patients. Several studies have previously reported the high prevalence of β-thalassemia in Pakistan, however, the prevalence of β-thalassemia in the siblings borne from β-thalassemia carrier parents and association of ABO blood group with β-thalassemia have not been extensively studied. The purpose of this study was to find out the prevalence of β-thalassemia in the siblings of β-thalassemia carriers parents. This study was also set to find out the association of β-thalassemia with ABO blood groups. This was a cross sectional study carried out from August 2016 to July 2017 in the Thalassemia centers of district Dadu and district Hyderabad. In this study, 168 children from 50 families were selected for the study. The results indicate that almost half of the births 44.64% from β-thalassemia carriers are the β-thalassemia patients. B blood group was found to be higher in both in male and female β-thalassemia patients. Male had higher prevalence of β-thalassemia than female children. The pattern of ABO blood group distribution was B > O > A > AB, and for the RH factor it was RH + ve > Rh –ve. Conclusively, this study indicates the higher prevalence of β-thalassemia in siblings borne from β-thalassemia carrier’s parents. β-thalassemia was higher in male children and B blood group was higher than other blood groups.

The influence of ABO blood group on mortality in major trauma.

ABO blood group has a profound influence on hemostasis as it is a major determinant of plasma levels of von Willebrand Factor. In vitro studies suggest that blood group O is a risk factor for increased severe bleeding while blood group non-O is a risk factor for thromboembolic events. Yet, the impact of ABO blood group outcome after multiple trauma is unknown. Retrospective multicenter case-control study from three level-1 trauma centers in Germany from 2012-2015. Inclusion criteria were severe trauma with an Injury severity score ≥9 and admission to an intensive care unit. 1281 patients (69.5% male) were included. Mean Injury Severity Score (ISS) was 21.1±12.4; mean age was 50.2±22.4 years. Distribution of blood groups was: O: 37.4%; A: 44%, B: 12.7 and AB: 5.8%. Hospital mortality depending on blood group was 9.7 (A), 10.4 (B), 6.8 (AB) and 12.7 (O) %. Multivariant logistic regression for mortality revealed an Odds ratio of 0.79 (A), 0.60 (B) and 0.54 (AB) without statistical significance (P=0.35 (A), 0.17 (B), 0.33 (AB)). Thromboembolic events (blood group O vs. others) occurred in 2.8 (O) vs. 3.3 (others) %, P=0.619.In this retrospective study on 1281 multiple injured patients, no relevant influence of ABO blood group on hemorrhage, thromboembolic events and mortality could be found.

Association of Bleeding Time and Clotting Time with ABO Blood Groups Among Healthy Adults

Background&#x0D; Haemostasis is the stoppage of bleeding. Bleeding time (BT) and Clotting time (CT) assess the integrity of haemostatic mechanisms. Assessment of Hematological parameters like bleeding time, clotting time and blood grouping are a very important before initiating any surgical procedure. Blood group has clinical importance in transfusion medicine and medico legal cases. Some studies have showed epistaxis and thrombosis found in O blood group individuals. Earlier studies showed the conflicting results regarding association of blood group with clotting time and bleeding time.&#x0D; Objectives&#x0D; The aim of the study was to assess the distribution of ABO blood groups in males and females with age group of 17-21yrs and determination of BT and CT among males &amp; females. To analyze the relationship between the blood groups, BT and CT.&#x0D; Method&#x0D; The study was conducted in Department of Physiology, Mamata Medical College. The study included 205 healthy volunteers of age group between 18-21years. Blood grouping, bleeding time and clotting time were determined. Statistical analysis done by un paired t test for calculating gender wise CT and BT and ANOVA and Post Hoc test for assessing relationship between BT, CT and blood groups.&#x0D; Results&#x0D; Our study results showed that blood group O was predominant in both males and females. Clotting time and bleeding time is statistically higher in females compared to males. Results showed clotting time is statistically significant (0.011) only between group A &amp; group O, with higher value in group O but not the bleeding time.&#x0D; Conclusion&#x0D; Blood group O was the most common group. BT and CT were higher in females than males. May be due to high estrogen and lower fibrinogen levels in females. CT and BT maximum in blood group O due to more activation of von Willebrand's Factor.

Keeping the blood flowing

The transfusion procedure is the last step in a multi‐process supply chain. The task of matching supply with demand requires donor managers to consider average consumption rates on a weekly or monthly basis, but to also have insight into variability in order distribution and possible attribute (blood groups) requirements. Since hospitals and blood banks are usually not deeply interwoven and often only ex‐post data are available, forecasting methods should be implemented. A thorough analysis of order pattern to set weekly target inventories and safety levels is required to close the information gap. A collection plan needs to identify possible bottlenecks which can be prevented through the planning of inter‐shipping, changes in message urgency and building of reserve donor pools. Constant analysis of collection and mobilization KPIs allows donor managers to implement the rolling‐wave planning approach and continually adapt to changing requirements, unexpected events and overall systematic variability. The variability happens on the demand side, as order quantities and their attributes, such as blood group distribution, are subject to change. However, also the supply is subject to significant variation, as donor response rates, attrition, deferrals and overall availability of donors are not constant. Unfavourable combinations of variable factors often lead to bottlenecks if only long‐term average values find their way into the planning process.

Frequency and Distribution of ABO and Rhesus Blood Group of Blood Donors

Frequency and Distribution of ABO and Rhesus Blood Group of Blood Donors

ABO blood group does not impact incidence or outcomes of surgery for acute type A aortic dissection

Objectives. To evaluate the distribution and impact of ABO blood groups on postoperative outcomes in patients undergoing surgery for acute type A aortic dissection (ATAAD). Design. A total of 1144 surgical ATAAD patients from eight Nordic centres constituting the Nordic consortium for acute type A aortic dissection (NORCAAD) were analysed. Blood group O patients were compared to non-O subjects. The relative frequency of blood groups was assessed with t-distribution, modified for weighted proportions. Multivariable logistic regression was performed to identify independent predictors of 30-day mortality. Cox regression analyses were performed for assessing independent predictors of late mortality. Results. There was no significant difference in the proportions of blood group O between the study populations in the NORCAAD registry and the background population (40.6 (95% CI 37.7–43.4)% vs 39.0 (95% CI 39.0–39.0)%). ABO blood group was not associated with any significant change in risk of 30-day or late mortality, with the exception of blood group A being an independent predictor of late mortality. Prevalence of postoperative complications was similar between the ABO blood groups. Conclusions. In this large cohort of Nordic ATAAD patients, there were no associations between ABO blood group and surgical incidence or outcomes, including postoperative complications and survival.

The ABO Blood Group System and Plasmodium Infection in Iran: A Comprehensive Study

Background: Geographical distribution of ABO blood groups affects by race, ethnicity, migration and some infectious agents, such as Plasmodium species. P. falciparum is the major causative agent of death in malaria that can affect ABO blood group distribution in different populations. Therefore, the objective of the current study was to determine the effect of p. falciparum on ABO blood group distribution in Iran.&#x0D; Materials &amp; Methods The present study was conducted on the database of Iranian Blood Transfusion Organization (IBTO) in 30 provinces of the country about ABO and Rh blood groups of the people who referred to health centers from June 2011 to August 2012. &#x0D; Results: A total number of 2124560 individuals were referred to IBTO in 30 provinces. The highest and lowest rates of O blood group were observed in Sistan &amp; Baluchestan (64.6%) and Lorestan (37.7%), respectively. P. falciparum was the most common species of malaria in Sistan &amp; Baluchestan (53215) and the rarest infection agent in Semnan province (20). The results showed statistically significant relationship (p &lt; 0.05) between prevalence of P. falciparum with O blood group, while this relationship for a blood group was not significant (p &gt; 0.05).&#x0D; Conclusion: Our results revealed a significant relationship between prevalence of P. falciparum and geographical distribution of ABO blood. There was also found more susceptibility and risk to malaria infection and cerebral malaria in a blood group compared to other groups. In addition, this was the first comprehensive study on the ABO blood group system and Plasmodium infection in Iran.

ABO blood group distributions in multiple sclerosis patients from Basque Country; O- as a protective factor.

BackgroundThe relation between ABO/Rh groups and multiple sclerosis (MS) has been proposed in several studies, however there is a controversy about the role of these groups in the disease. Although it has been reported that some groups can be protective or risk factors, there is no consensus and discordant reports can be found in the literature.Objectives and methodologyIn this short report, we analyze the ABO/Rh distribution in a MS cohort of 265 patients and compare these frequencies with the results obtained from the Basque Blood Donors bank (17,796 individuals) of the same region.Results and conclusionsFrom our data, the absence of immune antigens (A, B or Rhesus +) defined by the group O- seems to be protective in the MS group with an odds ratio of 0.49 (95% confidence interval 0.309–0.796), while the presence of Rh+ plus A or B seems to be a risk in developing multiple sclerosis.

Relationship between ABO blood group and Migraine

Objectives : Disorders related with ABO blood group are infectious disease (cholera, helicobacter pylori, echerichia coli), cardiovascular disease, malignancies and allergic status.We objectived to elucidate the association between ABO blood group and migraine. Materials and Methods : We investigated retrospectively the files of 985 adult patients who were diagnosed with migraine and had blood type between January 2008 and December 2018 in neurology outpatient clinics included in the study. The age, gender and blood group of the patients scanned and recorded retrospectively from the hospital data system. Results : Distribution of blood groups in patients as follows: A Rh+: 383(38.89 %), A Rh-: 53(5.38 %), B Rh+: 148 (15.03 %), B Rh-: 16(1.62 %), AB Rh+: 93(9.44 %), AB Rh-: 8(0.81 %), 0 Rh+: 257(26.09 %), 0 Rh-: 27(2.74 %). Conclusion : We found that in our study A Rh+ blood group was most prevelance blood group in migraine patients.