Background and objective: The current study aims to evaluate the glycemic index of local honey and date intake in healthy adults. Methods: The study was conducted on 24 healthy volunteers. They were given 50 g of carbohydrates from Haji Omeran local honey, Khudri (or Khadrawi) local date and reference food (white bread). The average body mass index and age of volunteers are almost similar. The blood samples were collected from finger capillaries to assess the glucose levels by using glucometer at selected time points (0, 15, 30, 60, 90, and 120 minutes). The data was recorded and statistically analyzed by one-way ANOVA and Duncan comparison. Results: The study results showed that the glycemic index of the honey and date is classified as a medium glycemic index, referring to their high carbohydrates content. The results also indicated that honey and dates have significantly different effects (P<0.05) on the blood glucose responses compared to reference food (white bread) in healthy subjects. The mean blood glucose levels after honey ingestion were higher than that when the date was ingested and lower than that of the reference food. In addition, the blood glucose responses for different foods in the study for females and males are not significantly different (P>0.05). Conclusions: In conclusion, eating behavior regarding honey and date consumption, particularly portion size and ingestion timing, is essential to manage blood glucose levels. Thus, glycemic index values should be considered in promoting a healthy lifestyle from chronic related metabolic disorders especially, diabetes mellitus, cardiovascular disease, and obesity.