Biphenyl Group Research Articles

Organosoluble thermoplastic polyimide with improved thermal stability and UV absorption for temporary bonding and debonding in ultra-thin chip package

Thermoplastic polyimide (TPI) has been extensively applied in electronic industry due to improved processibility, superior mechanical and dielectric properties. However, TPI is still restricted by the limited thermal stability and insufficient UV absorption for the application of temporary bonding and debonding (TBDB) in ultra-thin chip package. In this work, the rigid biphenyl group, twisted non-coplanar structure, rigid bulky side group and flexible ether bond are introduced to obtain a series of novel quaternary copolymerized TPIs with superior comprehensive performance. The results show that the as-prepared TPI possesses excellent solubility in NMP, DMF, DMAc and DMSO, and thermoplasticity (E’ drop > 103 MPa). Besides, the temperature of 5% weight loss and glass transition temperature could achieve as high as 548.1 °C and 335.4 °C, respectively. Furthermore, the tensile strength of TPI-4 is 128.7 MPa and elongation at break is about 14.2%. Moreover, the TPI-4 also exhibits superior adhesion on silicon wafer (adhesion strength >5 B by hundred grid test) and wonderful absorption at 355 nm UV laser (99.7%). At last, the application in TBDB process has also been proved with a laser energy of 400 mJ/cm2 within 60 s, showing superior efficiency and low-cost. All these results prove their application in TBDB of ultra-thin chip package for 5G era and so forth.

Role of π-conjugated-length-regulated perovskite intergrain interconnecting in the photovoltaic performance of perovskite solar cells

Despite great advancements in perovskite solar cells (PSCs), the unsatisfactory intergrain interconnecting in polycrystalline perovskite films remains a challenge to be addressed. Herein, three bilateral dicarboxyic acids, i.e. suberic acid (SA), p-phthalic acid (PTA) and biphenyl dicarboxylic acid (BPDA), are employed as additives to uncover the role of π-conjugated-length-regulated intergrain interconnecting in PSCs. Benefiting from strong interactions between two-sided carboxyl groups and perovskites, incorporation of these additives can control crystal growth, passivate defects/traps and tighten the interconnecting of perovskite grains. Moreover, thanks to the large π-electron delocalization and π-π interactions, introduction of π-conjugated additives (i.e. PTA and BPDA) can evidently intensify the preferred orientation of perovskite crystals and improve the carrier transport between perovskite grains. Especially, by extending π-conjugated structure to biphenyl groups (i.e. BPDA), high-quality perovskite films exhibiting large and ordered grains with vertically columnar alignment, along with strong electrical intergrain interconnecting, are obtained. Moreover, the intrinsic hydrophobicity nature of π-conjugated structures is helpful for improving the moisture stability. Eventually, the champion efficiency of 20.87% is acquired with negligible hysteresis and excellent moisture stability for PSCs with BPDA. Our work demonstrates that the π-conjugated length of additives can play a vital role in regulating the intergrain interconnecting.

Single-walled zeolitic nanotubes.

We report the synthesis and structure of single-walled aluminosilicate nanotubes with microporous zeolitic walls. This quasi-one-dimensional zeolite is assembled by a bolaform structure-directing agent (SDA) containing a central biphenyl group connected by C10 alkyl chains to quinuclidinium end groups. High-resolution electron microscopy and diffraction, along with other supporting methods, revealed a unique wall structure that is a hybrid of characteristic building layers from two zeolite structure types, beta and MFI. This hybrid structure arises from minimization of strain energy during the formation of a curved nanotube wall. Nanotube formation involves the early appearance of a mesostructure due to self-assembly of the SDA molecules. The biphenyl core groups of the SDA molecules show evidence of π stacking, whereas the peripheral quinuclidinium groups direct the microporous wall structure.

Tunable electrochromic behavior of biphenyl poly(viologen)-based ion gels in all-in-one devices

Electrochromic (EC) materials have attracted considerable attention for various applications, such as smart windows, information displays, and functional energy storage devices. In particular, poly(viologen) are promising EC materials owing to their flexible color tunability depending on the N -substituents and molecular weight. In this study, a new poly(viologen) containing biphenyl group and viologen (denoted as BP-poly(viologen)) was synthesized and employed in ion gel-based-EC devices (ECDs). Hydroquinone (H 2 Q) was used as the anodic species, and the H 2 Q/BP-poly(viologen) mole ratio was adjusted to obtain a balanced charge for the desired redox states of BP-poly(viologen). The resulting ECDs exhibited three different colors depending on the redox states of BP-poly(viologen): orange (dications), green (radical cations), and purple (neutral species). Color-switchable EC displays with various patterns were demonstrated using electro-force-assisted dispensing printing. • An electrochromic (EC) polymer based on biphenyl and viologen (BP-poly(viologen)) was synthesized. • The BP-poly(viologen) ion gels-based EC devices exhibited tunable EC behavior. • Color-switchable EC displays were fabricated by printing BP-poly(viologen).

Nanoassemblies formed from amphiphilic pillar[5]arene–rod–coil macromolecules in water for the detection of aliphatic diamines

An amphiphilic pillar[5]arene–rod–coil macromolecule (H1) composed of pillar[5]arene, biphenyl, and oligo(ethylene oxide) groups, was synthesized, and its applicability as a soft material for detecting aliphatic diamines was verified. Amphiphile H1 self-assembled into unique nanorings and shows an obvious lower critical solution temperature effect in aqueous solution. Interestingly, nanoaggregates of H1 exhibit certain aggregate-induced emission properties owing to the presence of ten electron-rich biphenyl units on the upper and lower sides of the pillar[5]arene block. In addition, various nanoassemblies were precisely constructed from H1, through the addition of small molecules with electron-acceptor units. This implies that charge-transfer interactions and hydrophilic/hydrophobic effects cooperatively influence the morphology of H1 to form diverse nanoassemblies in water. Moreover, macromolecule H1 with the pillar[5]arene block has a good ability to form host–guest complexes with aliphatic diamines in water, with high selectivity; this significantly affects the process of supramolecular nanoassembly.

Synthesis of benzidine-based conjugated organic materials bearing donor-acceptor groups: DFT studies and photovoltaic applications

Herein, tetraethoxymethyl, diphenyl, and dipyrenyl units have been fused with biphenyl group, via diimine bond, resulting in 3 (2 novel) benzidine derivatives 2, 4a-b. The derivatives were successfully synthesized by condensation of three different aldehydes (formaldehyde, benzaldehyde 3a, and pyrenecarboxaldehyde 3b) with benzidine in high yields. Structural identifications of the newly obtained compounds are determined by NMR, IR, UV–Vis, and HRMS spectroscopic techniques. Then, the photovoltaic properties of the organic compounds were investigated. To obtain insight into the geometric, electronic, and spectroscopic features of compounds 2, 4a-b, theoretical calculations were performed utilizing the B3LYP/6–311G(2d,2p) basis set. Theoretical 1H and 13C NMR resonance signals of compounds 2, 4a-b were estimated in the gas phase and the IEFPCM model in solvent field calculations utilizing the GIAO method at the B3LYP/6–311G(2d,2p) level and showed excellent correlation with the experimental results. A comparison of computed and experimental vibrational frequencies was performed, and significant bands were allocated. The results showed that experimental and theoretical IR frequencies had a good correlation (R2=0.9997 (2), 0.9996 (4a), and 0.9940 (4b)). To explain the relationship between the molecular structure of the compounds and photovoltaic properties, density functional theory (DFT) and its time-dependent form (TD-DFT) were utilized. The HOMO-LUMO energies and energy gap (Eg) helped understand optimal energy levels for electron absorption and transfer. The calculated band-gap of compounds 2, 4a-b were 4.705, 3.679, and 3.006 eV, respectively. The power conversion efficiency (PCE) values for the compounds 2, 4a-b were also calculated as 2.25, 2.70, and 2.80%, respectively. Compared to compounds 2 and 4a, dipyrenyl-bearing benzidine derivative 4b showed a larger redshift in the absorption wavelength with a remarkable high PCE value along with a low Eg value, which can be attributed to the greater stability of 4b due to the extended π-conjugation.Therefore, compound 4b with the d-A-π-A-D architecture is a potential candidate as useful electron transport material for DSSCs.

Construction of nanoaggregates from amphiphilic supramolecules containing barbiturate and Hamilton wedge units

AbstractThe study of supramolecular morphology is gaining significant attention. This may be attributed to the fact that nanostructures of aggregates have been found to significantly influence the photoelectronic properties of supramolecular materials. In this study, the self‐assembling behaviour of rod–coil molecules with barbiturate (Ba) or Hamilton wedge (Hw) units and the supramolecule Ba‐Hw was investigated. In chloroform solution, molecule Hw consisted of an oligo‐ethylene chain with degree of polymerization of 17 as well as biphenyl, phenyl and Hw units. Ba molecules incorporated octyloxy, biphenyl, phenyl and Ba groups that self‐organized into nanofibres with different diameters. Supramolecular amphiphile Hw‐Ba self‐aggregated into different sizes of nanosheet‐like aggregates. In a dimethylsulfoxide/H2O (1:19 v/v) mixed polar solvent, molecules Hw and Ba aggregated into twist‐shaped and nanosheet aggregates, while the supramolecular Hw‐Ba aggregated into larger‐size microtubes. Experimental results obtained for these molecular assemblies suggest that combining Ba and Hw units by employing hydrogen bonds is an effective strategy for forming amphiphilic supramolecules. Compared with the individual rod–coil molecules Ba and Hw, supramolecule Hw‐Ba has stronger π–π intermolecular forces due to the presence of more planar Hw‐Ba building blocks, which form various supramolecular assemblies with less curvature than the rigid and flexible surfaces of the original molecules. © 2021 Society of Industrial Chemistry.

Boosting the CO2 capture efficiency through aromatic bridged organosilica membranes

CO2 capture have attracted much attention due to serious environmental problems caused by excessive CO2 emission. Membrane-based technologies boasting of energy-saving and high-efficiency advantages exhibit much prospect in treating this issue. Benefited from excellent molecular sieving properties and high porosity, a wide variety of organosilica membranes were applied to the CO2 separation process. Nevertheless, most studies focused on the development of linear alkanes bridged organosilica membranes. Few researchers were dedicated to developing organosilica membranes with aromatic groups. In fact, the aromatic groups (e.g., such as benzene groups) functionalized organosilica precursors can endow derived membranes with robust network structures. Moreover, aromatic benzene groups can provide infinite possibilities of decoration. Herein, organosilica membranes fabricated using phenyltriethoxysilane (PhTES) with pendant benzene group, bis(triethoxysilyl)benzene (BTESB) with bridged benzene group and 4,4′-bis(triethoxysilyl)-1,1′-biphenyl (BTESBPh) with bridged biphenyl group, were used for CO2 capture separation. The effect of the location of aromatic benzene groups (bridged or pendant type) and the number of aromatic bridges (single benzene and biphenyl bridges) were evaluated in detail. For CO2/N2 mixtures separation at 50 °C, PhTES membranes displayed a CO2 permeance of 1087 GPU (1GPU = 3.348 ✕ 10−10 mol m−2 s−1 Pa−1) and CO2/N2 selectivity of 30. In contrast, BTESB membranes maintained a similar level of CO2/N2 selectivity of 34 but approximately 2.5 times enhanced CO2 permeance of 2600 GPU. BTESBPh membranes featured an unprecedentedly high CO2 permeance of 5465 GPU and CO2/N2 selectivity of 13. This clearly indicated that the aromatic functionalized organosilica membranes presented great potential in CO2 capture applications. Furthermore, the gas permeation properties of organosilica membranes can be finely tuned via the change of the location and the number of the benzene groups.

Facile Synthesis and Redox Behavior of an Overcrowded Spirogermabifluorene

A spirogermabifluorene that bears sterically demanding 3,3′,5,5′-tetra(t-butyl)-2,2′-biphenylene groups (1) was obtained from the reaction of in-situ-generated 2,2′-dilithiobiphenylene with GeCl2·(dioxane). The solid-state structure and the redox behavior of 1 were examined by single-crystal X-ray diffraction analysis and electrochemical measurements, respectively. The sterically hindered biphenyl ligands endow 1 with high redox stability and increased electron affinity. The experimental observations were corroborated by theoretical DFT calculations.

Bis-Argentivorous Molecules Bridged by Phenyl and 4,4'-Biphenyl Groups: Structural and Dynamic Behavior of Silver Complexes.

Bis-argentivorous molecules (La and Lb), which have phenyl and 4,4'-biphenyl groups as linkers, have been prepared. The structures of Ag+ complexes with the new ligands (La and Lb) were investigated in solution and the solid state. The CSI-MS and 1H NMR titration of La and Lb with Ag+ show 1:1 and 1:2 complexes depending on the [Ag+]:[L] ratios. In the solid-state structures, single crystals of La and Lb with 2 equiv of Ag+ were prepared. X-ray crystallography of the silver(I) complexes with La and Lb showed that an intramolecular racemic structure (Δ(δδδδ)Λ(λλλλ) form) and a racemic mixture of Δ(δδδδ)Δ(δδδδ) and Λ(λλλλ)Λ(λλλλ) forms were formed, respectively. The dynamic 1H NMR studies suggest the following: (i) the activation entropies (ΔS⧧) of the side arm rotations in the Ag+ complex with La were all negative, indicating restricted rotation of the side arms due to their shortness, and (ii) the ΔS⧧ values of the Ag+ complexes with Lb were negative only when the side arms of both cyclens rotated simultaneously, and the ΔS⧧ values for the 1:1 and 1:2 complexes were positive when one cyclen side arm was rotated. These values of ΔS⧧ indicate that the biphenyl side arms between the two cyclens are not long enough to rotate the ring freely.

Improving the Intrinsic Thermal Conductivity of Epoxy Resin by Synergistic Effect between Rigid Groups and Hydrogen Bonds

AbstractAlthough introducing liquid crystal phase into epoxy resin for liquid crystal epoxy fabrication is one of the most conventional methods for improving the intrinsic thermal conductivity of epoxy resin, the complex molecular structure design and sophisticated synthesis process seriously limit its rapid expansion and further industrial application. Herein, the rigid groups of 4’4‐dihydroxybiphenyl were introduced into the main chain of epoxy resin by ring‐opening polymerization (ROP) to change the molecular structure of epoxy resin. The introduction of biphenyl groups enhances the “orderliness” of molecular structure and forms hydrogen bonds between molecules, which facilitates the transmission of phonons within the molecule. The intrinsic thermal conductivity of modified epoxy resin (MEP) reaches 0.29 W m−1 K−1. After adding the expanded graphite (EG) into the MEP matrix, the thermal conductivity of MEP/EG reaches 2.59 W m−1 K−1, which is 1133 % higher than that of EP. In addition, the MEP also has certain advantages in harsh environment, the |Z|0.01 Hz of MEP coating is higher than 1.4 times the value of EP coating after immersing in 3.5 wt% NaCl solution for ten days, which identified the excellent anticorrosion of MEP. The MEP prepared by this method can find great applications as heat conduction materials in harsh environment.

High-performance multiblock PEMs containing a highly acidic fluorinated-hydrophilic domain for water electrolysis

The present paper describes the design and evaluation of novel hydrophilic–hydrophobic poly(arylene ether sulfone) (PAES) multiblock copolymers for their synergistic effects upon transport properties and their potential use in proton exchange membrane water electrolysis. The multiblock copolymers are prepared via a coupling reaction between (i) a hydrophilic segment consisting of a disulfonated quinone fluorinated biphenyl group that contains fluorine moieties next to the sulfonated groups to increase the acidity, and (ii) hydrophobic segments composed of non-sulfonated biphenyl sulfone to provide dimensional stability. Two different lengths (molecular weights; 5 k and 10 k, where k represents 103 g mol-1) of hydrophobic segments are used to investigate the effects of the membrane properties compared with those of Nafion® and PAES random copolymer (i.e., BPSH40). Atomic force microscopy images of the BPSH40 and multiblock membranes are shown to agree closely with a mesoscale simulation, thus confirming the importance of the morphological effect upon the transport properties. Moreover, the multiblock copolymer with a higher proportion of hydrophilic segments (10 k–5k) was shown to provide enhanced performance (3.41 A cm-2 at 1.9 V) compared to the multiblock copolymer with equal proportions of hydrophilic and hydrophobic segments (10 k–10 k) due to the greater continuity of nano-sized ionic channels.

Asymmetric phthalocyanine compounds in the structure D-π-A containing cyano groups: Design, synthesis and dye-sensitized solar cell applications

In this study, asymmetric zinc phthalocyanine compounds with Donor-π-Anchor (D-π-A) property that enable the movement of electrons in molecular structure in one direction were synthesized. Phthalocyanines were designed to ensure electron mobility within the molecule and to facilitate the transfer of electrons to the TiO2 layer. The synthesized asymmetric zinc phthalocyanines (ZnPc-1 and ZnPc-2) are molecules with three donor biphenyls and one anchor aldehyde group and three acceptor/anchor cyano and one anchor aldehyde group, respectively. The effect of biphenyl and cyano groups on cell efficiency with aldehyde anchor group was investigated. The structure of the synthesized phthalocyanines was characterized by Fourier Transform Infrared Spectrometry (FTIR), Mass Spectrometry (MS), UV-vis, Fluorescence spectroscopy. The experimentally calculated optical band gap values were supported by the values found by Density Functional Theory (DFT) calculations. dye sensitive solar cells were measured and the efficiencies were evaluated with reference to the N719 standard dye. In the solar cell measurements of the designed phthalocyanines, the structure containing the cyano group has been given a higher photovoltaic cell thanks to the higher short circuit photo-current (Jsc). In this way, the highest power conversion efficiency value was achieved among the cyano group molecules.

Cyclic Diplatinum Complex with a Tröger's Base Ligand and Reductive Elimination of a Highly Strained Ring Molecule

The cover picture shows the structures of Tröger's base derivatives in this study. Tröger's base has a compact molecular structure with two chiral nitrogen atoms (upper left). A cyclic diplatinum complex with C-bonded Tröger's base ligand is synthesized and characterized (lower left). This complex undergoes reductive elimination of the cyclic dimer of Tröger's base (bottom right). Due to the conjugated biphenylene groups, the molecule contains the angle between the aromatic planes of Tröger's base, 65–66°, which is much smaller than those previously reported for Tröger's base derivatives (88–114°) (https://doi.org/10.1002/zaac.202100085).

Dinuclear Fe(III) Hydroxypropyl-Appended Macrocyclic Complexes as MRI Probes.

Four high-spin Fe(III) macrocyclic complexes, including three dinuclear and one mononuclear complex, were prepared toward the development of more effective iron-based magnetic resonance imaging (MRI) contrast agents. All four complexes contain a 1,4,7-triazacyclononane macrocyclic backbone with two hydroxypropyl pendant groups, an ancillary aryl or biphenyl group, and a coordination site for a water ligand. The pH potentiometric titrations support one or two deprotonations of the complexes, most likely deprotonation of hydroxypropyl groups at near-neutral pH. Variable-temperature 17O NMR studies suggest that the inner-sphere water ligand is slow to exchange with bulk water on the NMR time scale. Water proton T1 relaxation times measured for solutions of the Fe(III) complexes at pH 7.2 showed that the dinuclear complexes have a 2- to 3-fold increase in r1 relaxivity in comparison to the mononuclear complex per molecule at field strengths ranging from 1.4 T to 9.4 T. The most effective agent, a dinuclear complex with macrocycles linked through para-substitution of an aryl group (Fe2(PARA)), has an r1 of 6.7 mM-1 s-1 at 37 °C and 4.7 T or 3.3 mM-1 s-1 per iron center in the presence of serum albumin and shows enhanced blood pool and kidney contrast in mice MRI studies.

Crystal structure and photoreactive behaviour of N,N-diisoprop-yl(p-phenyl-phen-yl)glyoxyl-amide.

The title compound [systematic name: 2-([1,1'-biphen-yl]-4-yl)-2-oxo-N,N-bis(propan-2-yl)acetamide], C20H23NO2 was synthesized and its photoreactive properties in the crystalline state and in aceto-nitrile solution were investigated. The compound crystallizes in the chiral space group P212121. The crystal does not react under UV light irradiation, perhaps due to the presence of the biphenyl group. However, the compound is photoreactive in aceto-nitrile solution to give racemic 3-(p-phenyl-phen-yl)-3-hy-droxy-N-isopropyl-4,4-di-methyl-azetidin-2-one.

Thermal and Emission Properties of a Series of Lanthanides Complexes with N-Biphenyl-Alkylated-4-Pyridone Ligands: Crystal Structure of a Terbium Complex with N-Benzyl-4-Pyridone

This work focuses on the investigation of the liquid crystalline behavior and luminescence properties of the lanthanide complexes of Eu(III), Sm(III) and Tb(III) with N-biphenyl-alkylated-4-pyridone ligands. The organic ligands having a biphenyl group attached via a long flexible spacer with either 9 or 10 carbon atoms were synthesized by the reaction between 4-hydroxypyridine and the corresponding bromide compounds. The chemical structures of the organic and lanthanide complexes were assigned based on elemental analysis, single-crystal X-ray diffraction, 1H, 13C NMR and IR spectroscopies, and thermogravimetric analysis (TGA). The X-ray diffraction analysis of a parent compound shows that the lanthanide ions are surrounded by three monodentate pyridone ligands and three bidentate nitrate ions, giving a 9-coordinate environment. The mesogenic behavior and the type of liquid crystalline phases exhibited by the new complexes were analyzed by differential scanning calorimetry (DSC) and polarizing optical microscopy (POM), and powder X-ray diffraction (XRD) studies. Only the lanthanide complexes with longer spacer (10) display a monotropic SmA phase, typically on a short thermal range (less than 10 °C). The complexes with shorter flexible chains (9) show no liquid crystalline properties with melting temperatures lower than their analogs with longer spacers. The emission spectra recorded in solid state at room temperatures show typical emission bands for each lanthanide ion employed (Eu(III), Tb(III) and Sm(III)).

In silico analysis of resveratrol induced PD-L1 dimerisation

T-cell activation through the blockade of PD-1 – PD-L1 interactions is recognised at present as one of the most promising strategies in the cancer treatment and a number of antibodies targeting the PD-1 – PD-L1 immune checkpoint pathway have been approved after successful clinical trials. However, the use of antibodies suffers from a number of shortcomings including poor tissue and tumor penetration, long half-life time, poor oral bioavailability, and expensive production costs. Small molecule based therapeutic approaches offer the potential to address the shortcomings of the antibody-based checkpoint inhibitors. At present, more than twenty small molecular inhibitors of the PD-1 – PD-L1 interactions whose scaffold is based on substituted biphenyl group connected to a further aromatic ring through a benzyl ether bond have been identified and patented by Bristol – Mayers – Squibb (USA). Structural studies have shown that all these compounds act by inducing the dimerisation of PD-L1 that makes PD-L1 non-competent for forming complex with PD-1. Very recently, the dietary polyphenol resveratrol (RSV) has been reported to inhibit the PD-1 – PD-L1 interactions through the induction of the PD-L1 dimerisation but the mechanisms remain unclear. Here, computational structural biology tools combining protein – protein and protein – ligand docking with molecular dynamics simulations were used to gain structural insights into the mechanisms of the RSV-induced dimerisation of PD-L1.

Synthesis and properties of a benzoxazine monomer containing maleimide and biphenyl groups

Benzoxazine resin exhibits excellent properties and is widely used in many fields. Herein, the synthesis of a novel compound, the bis(2,4-dihydro-2 H-3-(4- N-maleimido)phenyl-1,3-benzoxazinyl)biphenyl (BMIPBB), has been reported, which was synthesized by reacting N-(4-aminophenyl)maleimide (APMI), formaldehyde, and 4,4’-dihydroxybiphenyl. 1,3,5-three(4-(maleimido)phenyl)-1,3,5-triazine (TMIPT) was formed as an intermediate during the reaction. The proton nuclear magnetic resonance (1H-NMR) and Fourier transform-infrared (FTIR) spectroscopy experiments were conducted to determine the structure of BMIPBB. BMIPBB was obtained as a reddish-brown solid in 40.1% yield. The thermal properties of BMIPBB were investigated using differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) techniques. Analysis of the DSC curves revealed that the broad peak representing the release of curing reaction heat appeared in the temperature range of 140–330°C. The peak temperature was 242.59°C and the heat of the reaction was 393.82 J/g, indicating that the rate of the curing reaction was low and the heat of the reaction was high. Analysis of the TGA results revealed that the weight loss rate was 5% at 110°C. The monomer exhibited a significant weight loss in the range of 320–500°C. The compound lost 50% of its weight at a temperature of 427°C.

“Double-Twist”-Based Dynamic Induction of Optical Activity in Multichromophoric System

The electronic circular dichroism (CD)-silent 2,5-bis(biphen-2-yl)terephthalaldehyde has been used as a sensor (reporter) of chirality for primary amines. The through-space inductor–reporter interactions force a change in the chromophore conformation toward one of the diastereomeric forms. The structure of the reporter, with the terminal flipping biphenyl groups, led to generating Cotton effects in both lower- and higher-energy regions of the ECD spectrum. The induction of an optical activity in the chromophore was due to the cascade point-to-axial chirality transmission mechanism. The reporter system turned out to be sensitive to the subtle differences in the inductor structure. Despite the size of the chiral substituent, the molecular structure of the inductor–reporter systems in the solid-state showed many similarities. The most important one was the tendency of the core part of the molecules to adapt pseudocentrosymmetric conformation. Supported by a weak dispersion and Van der Waals interactions, the face-to-face and edge-to-face interactions between the π-electron systems present in the molecule were found to be responsible for the molecular arrangement in the crystal.