Multidisciplinary research is the hallmark in 21st century and a way forward towards holistic sustainability. Ancient philosophers viz; Aristotle, Socrates, Confucius, Al-Farabi, Sigmund Freud, Jabar-bin-Hayan, Benjamin Bloom, Karl Marx and Friedrich Nietzsche laid foundations of philosophies based on their intellectual multidisciplinary knowledge approach. The promising impact of multi-scientific disciplines demonstrate the importance of diverse academic and research domains. In fact, every discipline is interrelated and interdependent to each other with a minute hairline difference. MDR unites scientists globally from distinct academic backgrounds to address pressing challenges of next decade, but no doubt cooperation is crucial in scientific study as it stimulates innovation, creativity, and systematic conception. Present review emphasizes importance of transdisciplinary research in diverse meta-problems, tackling future challenges and multi-faceted complexities. Emerging technology has made it possible for scientists and scholars from various purviews around the world to collaborate on projects and research without being at the same location. The most significant recommendation of this article highlights the future scope of transdisciplinary approach by inclusion of collaborative research meeting sustainable development goals (SDG’s) through multi research, thereby aligning researchers and scientists towards internationalization.
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