Benha University Hospital Research Articles

Assessment of Macular and Retinal Nerve Fiber Layer Changes after Uncomplicated Phacoemulsification Surgery in Diabetic Patients Using Optical Coherence Tomography

Background: Macular edema (ME) is a major cause of vision loss after cataract surgery in patients with diabetes. In this study we aimed to assess the macular and retinal nerve fiber layer changes after uncomplicated cataract surgery in the early postoperative period in diabetic and non-diabetic patients. Methods: This is a comparative cross-sectional study conducted on patients with cataract, included 30 patients divided into 2groups: Group 1 (Study group): Diabetes mellitus group (DM group) consists of 15 eyes with cataract (15 diabetic patients without diabetic retinopathy). Group 2 (Control group): non diabetic group consist of 15 eyes with cataract (15 nondiabetic patients). Preoperative and 30 days postoperative OCT measurements were compared. All patients were admitted for cataract surgery (phacoemulsification) and posterior chamber intraocular lens (IOL) in Ophthalmology Department Benha University Hospital. Results and conclusion: The mean (±SD) age of diabetic group was 57.7 (±6.4). They were 6 males (40%) and 9 females (60%). While the mean (±SD) age of non-diabetic group was 60.2± (9.5). They were 9 males (60%) and 6 females (40%). Both groups were matched regarding age and gender (p>0.05 for both). Our data indicated that, although in each group; there is a significant increase in MFT and peripapillary RNFL postoperatively. However, there is a significant statistical difference between both groups regarding MFT and peripapillary RNFL after 30 days postoperative. Also there is improvement in BCVA progressively postoperative in each group, but there is a statistical significant difference between both groups.

Comparison Between Nasal High-Frequency Oscillatory Ventilation And Nasal Continuous Positive Airway Pressure In The Management Of Respiratory Distress Syndrome

Context: A neonatal respiratory distress syndrome occurs at or soon after delivery (<24 hours). Premature newborns with respiratory distress syndrome (RDS) often need breathing assistance. There has been a tendency to reduce in the previous decade the use of non-invasive ventilation modes (NIV) in neonatal intensive care units to prevent ventilator-induced lung damage, in particular after recent data showing NIV in preterm babies has equivalent efficiency compared to EMV. In practical practise, different forms of NIV may be employed include nasal continuing positive airway pressure and noninvasive intermittent positive airway pressure. Nasal continuous positive airway pressure is one of the most often utilised non-invasive techniques (NCPAP). Although HFV has been used in several neonatal critical care units, a relatively novel modality of nasal high frequency oscillatory ventilation (nHFOV) is limited in evidence of its utility. The objective of this research has been to examine the effectiveness and safety of nasal oscillatory ventilation with nasal airway continuous pressure in preterm baby respiratory distress syndrome therapy. Methods: This research is a (60 instances) clinical experiment conducted with respiratory distress syndrome (admitted to the Benha University Hospital Neonatal Intensive Care Unit and Benha Kids Hospital) between the 1–28 day age range. Cases were randomly picked in two groups: Group I: 30 instances of high-frequency oscillatory nasal ventilation were treated (nHFOV). Group II: 30 individuals with constant nasal airway pressure were treated (NCPAP). Methods: Detailed history of medicine. Total usage time NHFV and NCPAP usage time and oxygenation time required for each instance. Complication detection occurs during non-invasive breathing (pulmonary air leak syndrome, IVH, nasal injury and other.) Studies of imagery. Outcomes: There was no statistically significant difference in demographic data between the two groups. There was a statistically significant difference in IVH complication between Group I and Group II. The percentage of nasal septal injuries in Group I was significantly lower than in Group II. The rate of intervention failure (intubing and ventilator demand) in Group I was significantly lower than in Group II (3.3 percent, (26.6 percent) p value=0.030. Conclusion: High frequency nasal ventilation has a greater impact than continuous airway pressure on infants and is less complicated. This research revealed that the length of non-invasive respiratory support was greatly shortened by high frequency nasal ventilation and the necessity for intubation was minimised compared to the continuous positive airway pressure of RDS infants.

Enhance Nurse Managers' Legal and Ethical Aspects at Benha University Hospital

Backgrounds: Nurse managers' are facing the challenges in their daily practice such as short ofstaffing, workload and maintenance of high quality and encounter many legal and ethical issuessurrounding these area. Law defined as a legal document setting rules governing a particular kind ofactivity while ethics are moral principles that govern how the person or a group will behave. Aim ofthe study: Was to enhance nurse managers' in the legal and ethical aspects at Benha UniversityHospital. Research design: A quasi-experimental design was utilized. Sample: Composed of 79nurse managers include nursing director (1), supervisors (14), and first line manager (64). Setting:The study was conducted in all units (44) at Benha University Hospital. Tools for data collectionTwo tools were used; the first tool: legal and ethical aspects knowledge questionnaire sheet. Thesecond tool: legal and ethical aspects observational checklist. Results: Majority of the studiedsample had unsatisfactory knowledge level about legal and ethical aspects at preprogram, whileimmediate post educational program the majority of them had satisfactory knowledge level. Also, theminority of the studied sample pre educational program demonstrated complete performance aboutlegal and ethical aspects, while post program the majority of them improved their performance.Additionally there was astatistical significant positive correlation between nurse managerg’s totalknowledge scores and performance scores. Conclusion: There were an improvement in level ofknowledge and performance of the nurse mangers about legal and ethical aspect immediately postand follow-up implementation of educational program compared to pre-program.Recommendations: Establish an ethical and legal committee within the organization for all ethicaland legal aspects in nursing practice. Further research: effect of legal and ethical nurses’ knowledgeon patients outcome.

Assessment of Nurses Knowledge and Practices Regarding The Use of Evidence-based for Pregnant Women with Pre-eclampsia

Background: Once preeclampsia is diagnosed, evidence-based interventions may reduce the risk or severity of maternal and infant health outcomes of preeclampsia. Aim of the study: Was to assess nurses knowledge and practices regarding the use of evidence-based for pregnant women with pre-eclampsia. Design: A descriptive study design was utilized to achieve the aim of the study. Setting: The present study was conducted at obstetrical and gynecological department at Benha University Hospital. Sampling: A convenient sample. Tools: Three tools were used for data collection:A self-administered questionnaire, Observational checklist and Modified Likert scale. Result: There were more than one third of studied nurses(41.7%) had average level of total knowledge about EBP and preeclampsia, less than two third of studied nurses (65%) had satisfactory level of total practices regarding preeclampsia and more than half of studied nurses (53.4) had high level of awareness about barriers. Conclusion: There was statistical significance positive correlation between total practices, total knowledge about evidence based practices and total knowledge of preeclampsia. Recommendation: Improving nurse’s awareness regarding EBP through involving them in educational programs to encourage them to utilized EBP into patient daily care.

Mothers’ Care regarding Primary School Children with Primary Headache

Background: Primary headache is the most frequent neurological symptom and commonest manifestation of pain in children, between 30-40% of children report headaches at least weekly with subsequent impact at home and on school attendance and performance. The study aimed to assess mothers’ knowledge and care regarding primary school children with primary headache. Research design: A descriptive research design was utilized to conduct this study. Setting: The study was conducted at Pediatric Outpatient Clinics in Benha University Hospital. Sample: A purposive sample was used, it included 236 mothers accompanied with their children Tools: A structured interviewing questionnaire was used, it was consisted of three parts: Part I; a) socio-demographic characteristics of mothers, b) personal characteristics of children, c) medical history of children. Part II; Mothers’ knowledge regarding their children with primary headache. Part III; Mothers practices regarding their children with primary headache. Results: 57.2%of studied mothers aged from 20-30 years and 46.2% of them had basic education. 43.2% of mothers had average knowledge about primary headache, 59.7% of mothers had unsatisfactory practices about their children primary headache. Conclusion: There were statistically significant relations between mothers' total knowledge; total practice and their demographic characteristics. Also, there was significant relation between total mothers' practice and total knowledge. Recommendations: Health education program should be implemented at pediatric outpatient clinics to improve mothers' knowledge and practices regarding their children with primary headache.

Mental Health Outcomes Among Health Care Workers Exposed to Covid-19 Pandemic, Qalyoubia Governorate: Cross-Sectional Survey

Background: The pandemic caused by novel coronavirus disease 2019 (COVID-19) is considered the worst health crisis facing the entire world today. At the topmost of this crisis are the healthcare workers (HCWs) who are working to maintain well-being of all people. COVID-19 pandemic added more and more stress to healthcare workers in particular, depending on their work position. Objective: To assess mental health outcomes among HCWs dealing with confirmed or suspected COVID-19 patients. Methods: This is cross-sectional, hospital-based survey study conducted between Feb 6 and April 28, 2021. A total of 548 HCWs participated in the study. Mental health impact was assessed by using the 9- item Patient Health Questionnaire (PHQ-9), the 7-item Generalized Anxiety Disorder (GAD-7) and the 7-item Insomnia Severity Index (ISI) questionnaires. Multivariable logistic regression analysis was done to determine the risk factors of mental health outcomes. Results: Among the 548 HCWs surveyed;64.8% were nurses and 50.0% aged from 26-30 years old. About 52.0% worked in Benha University Hospital, 21.2% worked in Toukh Fever Hospital, and 26.8% worked in Qaha Central Hospital. A considerable proportion of HCWs had symptoms of anxiety, depression and insomnia. Nurses, workers aged from 26-30, those working in Qaha Central Hospital and those who had shift hours from 7–10 experienced more severe symptom levels of depression, anxiety, and insomnia. Nurses were associated with severe symptoms of anxiety, depression and insomnia. Conclusion: The COVID-19 pandemic represents a new working challenge for HCWs and intervention strategies to prevent depression and anxiety to reduce the risk of adverse mental health outcomes are needed. [ABSTRACT FROM AUTHOR] Copyright of Egyptian Journal of Hospital Medicine is the property of Egyptian Journal of Hospital Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Assessment the Domestic Violence among Infertile Women at Benha University Hospital

Assessment the Domestic Violence among Infertile Women at Benha University Hospital

Nurses' Application of International Patient Safety Goals at Accredited and Non-accredited Hospitals

Background: Patient safety is an essential component in the quality of patient care. Itremains a challenge for developing countries. Assessment of application of international patientsafety goals in healthcare organizations is becoming an integral component to improve patients'safety. The study aimed to assess nurses’ application of international patient safety goals ataccredited and non-accredited hospitals. Research design: A comparative design was utilized toconduct this study. Setting: The study was conducted at general intensive care units (ICU) in BenhaUniversity Hospital (non-accredited hospital) and Elaraby International Hospital (accreditedhospital). Sample: All available 112 staff nurses working at the above mentioned settingsdistributed as following 60 staff nurses at Benha University Hospital and 52 staff nurses' at ElarabyInternational Hospital. Tools for data collection: Three tools were used. I: Personal and workcharacteristics of studied staff nurses, II: International patient safety goals’ questionnaire and III:Observational checklist for international patient safety goals practice. Results: 97.8% & 94.3% ofstudied staff nurses had good knowledge and competently applied practice level at accreditedhospital respectively. While, 30.1% had good knowledge and 76.1%of them had incompetentlyapplied practice level at non-accredited hospital about international patient safety goals.Conclusion: There was a positive statistical significance correlation between studied staff nurses'knowledge and practice of international patient safety goals at accredited and non-accreditedhospitals. There was highly statistical significance difference between accredited and nonaccredited hospitals regarding knowledge and practice of international patient safety goals amongstudied staff nurses. Recommendations: Educational programs and training courses should bedeveloped and implemented for staff nurses' about application of international patient safety goalsand how it can be used to improve patient safety at non-accredited hospitals

Assessment of Pre and Postoperative Voiding Habits among Patients Undergoing Prostatectomy

Background: Prostatectomy is a common procedure to remove the prostate gland, most often for prostate adenocarcinoma, although occasionally performed for benign prostatic hyperplasia. This study aimed to: Assess the pre and postoperative voiding habits among patients undergoing prostatectomy. Research design: Descriptive research design was utilized in carrying out this study. Setting: The study was conducted at Benha University Hospital in Urology Department. Subjects: The study was conducted on 105 patients undergoing prostatectomy. Study tools:Data were collected by using two toolsI:Structured interviewing assessment to assess, patients' socio-demographic characteristics, patients' clinical information, and life style changes characteristics. II:Pre and postoperative voiding habits questionnaire Results: 40.0%of the studied patients aged 50 years old and more. 66.7% of them had total healthy lifestyle score.There were highly statistically significant differences in all items related the studied patients' voiding habits between pre and postoperative. There were highly statistically significant positive correlations between the studied patients' voiding habits and their lifestyle characteristics. Conclusion: There were highly statistically significant differences in all items related the studied patients' voiding habits between pre and postoperative. There were highly statistically significant positive correlations between the studied patients' voiding habits and their lifestyle characteristics related to dietary habits, smoking habits, personal hygiene, stress, and sexual practices. While there were no statistically positive correlations between the studied patients' voiding habits and their activities as well as exercises, sleep and comfort. Recommendations: This study recommended conducting a study on the aspects of patients and knowledge, attitude, and practices towards prostate cancer. Establishing of an educational program to improve health related quality of life for prostate cancer patients. The same study should be replicated for a large sample size from different geographical areas to generalize the results.

Effect of Managerial Innovation Educational Program for Head Nurses on their Professional Competency

Background: Managerial innovation is necessary at the workplace to enhance head nurse’s professional competency so head nurses need to adopt with clear and attainable system for managerial innovation in health care sector. The study aimed to assess the effect of managerial innovation educational program for head nurses on their professional competency. Design: A quasi- experimental design was utilized. Setting: The study was conducted at Benha University Hospitals in all medical and surgical buildings. Subjects: Consisted of 55 head nurses. Tools of data collection: Three tools were used in the present study for data collection, innovation knowledge questionnaire, managerial innovation skills questionnaire and professional competency questionnaire, Results: Minority of head nurses (12.7%) had good level of knowledge at preprogram phase while increased to more than two thirds (81.8%&70.9%) at post program and follow up study phases. The most (85.5%& 80%) of head nurses had high level on managerial innovation skills at post program and follow up phases respectively as compared to preprogram phase (14.5%). Most (81.8%& 70.9%) of head nurses had good professional competency at post program and follow up, respectively. Conclusion: There was a highly positive statistically significant correlation between head nurses' managerial innovation knowledge, skills, and level of professional competency at post and follow up program phases. Recommendations: Hospital management can organize educational programs for refreshing and increasing knowledge and skills about nurses' innovation as well as emphasizing managerial innovation skills of head nurses.

Mothers Perception regarding Poisoning among their Preschool Children

Background: Poisoning is a term used to describe an event where the poisonous substanceshave entered the body through breathing, mouth, blood vessels, eating, injections and leads to thedestruction and death of the body's cells. The aim of this study was to assess Mothers perceptionregarding poisoning among their preschool children. Research design: A descriptive study design wasutilized to conduct this study. Setting: This study was conducted at Toxicology Unit at BenhaUniversity Hospital in Benha City, Egypt. The sample: Purposive sample of 25% of all poisonedchildren attended the previously mentioned setting with their mothers (130 mothers). Tools of datacollection: Two tools were used, I. An interviewing questionnaire was used, It consisted of four parts:First part: Socio demographic characteristics of the mothers. This part included two items. A) Mother'sdemographic characteristics B) Child's characteristic. Second part: Was concerned with the child healthstatus. Third part: Was concerned with knowledge of mothers regarding to poisoning among theirpreschool age children. Forth part: An observational checklist was used to observe mothers׳preventivepractices. II. Scale to measure the attitude of mothers. Results: 60.7% of mothers had poor totalknowledge regarding poisoning among preschool age children, 67.7% of mothers had unsatisfactorytotal of reported practices about poisoning, 62.3% of mothers had total negative attitude aboutpoisoning of preschool children. Conclusion: There were a positive statistically significant correlationbetween total knowledge and attitude scores, between total knowledge and total reported practicesscores and between attitude scores and total reported practices regarding poisoning among theirpreschool age children. Recommendations: All possible forms of mass media should be utilized tohelp in disseminating information about poisoning in children.

Impact of Educational Program for Hepatic Encephalopathy on Nurses` Performance and Patients` Outcomes

Background: Hepatic Encephalopathy (HE) is life-threateningcomplication of liver disease occurs with liver failure and may result from theaccumulation of ammonia and other toxic metabolites in the blood. Aim of thestudy: Was to evaluate the impact of educational program for hepaticencephalopathy on nurse's performance and patient's outcomes. Research design: Aquasi-experimental research design will be utilized. Sample: All the availablenurses (40) who are caring for patients with hepatic encephalopathy regardless oftheir age and years of experience. Sample sizes of at least 50 patients with hepaticencephalopathy. The study was conducted at Intensive Care Units at BenhaUniversity Hospital. Tools were obtained through three main tools; StructuredInterview Questionnaire Sheet, Nurse's Observational Checklist for hepaticencephalopathy care and Patient's Outcomes Sheet. Results: There is a highlystatistically significant difference between knowledge and practice of studiedsubjects pre, immediate after implementation and 3 month post implementation ofdesigned hepatic encephalopathy program (P < 0.000**). There was a highlystatistically significant difference between nurse's performance and patientoutcome of designed hepatic encephalopathy program. Recommendation:Educational programs for nurses in ICU should be continuous for improve nurse'slevel.

Effect of Application of Health Promotion Model on Lifestyle of Women with Endometriosis

Background: Endometriosis is a life-threatening gynecological health problem in womenduring the reproductive age that cause chronic pelvic pain, infertility, dysmenorrhea, dyspareunia,dysuria and dyschezia. Aim: The study aimed to evaluate the effect of application of health promotionmodel on lifestyle of women with endometriosis. Design: Quasi-experimental study design (preposttest). Setting: The study was conducted at Obstetric and Gynecological out -patient clinic in BenhaUniversity hospital. Sample: A purposive sample consisted of 146 women with endometriosis. Theydivided control group comprised 73 women and study group comprised 73 women. Tools: Structuredself-administered questionnaire, health promotion lifestyle profile-II and patient's satisfaction sheet.Results: 65.8% of study group were highly satisfied of health promotion model compared to only 7.2%of control group, total health promotion lifestyle profile-II improved from 20% before programimplementation to 64.4% after program implementation among study group while there was noimprovement in the control group, nearly three quarters of both study and control groups respectivelyhad poor knowledge score about endometriosis before program implementation. Meanwhile, more thanthree quarters of study group had good knowledge score about endometriosis. Conclusion: The presentstudy showed that there was a highly statistical significant difference regarding all health promotionlifestyle profile-II items (health responsibility, physical activity, nutrition, spiritual growth,interpersonal relations and stress management) between study and control groups after programimplementation (P< 0.001). Application of health promotion model has positive effect on lifestyle ofwomen with endometriosis therefore, the study hypothesis was supported. Recommendation: Asimplified and comprehensive booklet should be available for all patients with endometriosis whichinclude a clear, brief and simple explanation about non pharmacological modalities to reduceendometriosis related pain._____________________________

Efficacy of the Free-Style, Perforator-Plus Flaps in the Reconstruction of the Soft Tissue Defects at the Lower Leg and Ankle Regions

ABSTRACTBackground: Reconstruction of the lower leg and ankle soft tissue defects is not that the convenient task, due to the unique anatomy and its variation. Aim of Study: Evaluation efficacy of the Free-Style, Perforator-Plus flap concepts in the reconstruction of the soft tissue defects at lower two-thirds leg, tendo-Achilles and ankle regions.Method: A Prospective (Case Series) Study, was carried on 20 consecutive patients, which performed at the Plastic and Reconstructive Surgery Unit, of General Surgery Department, of Benha University Hospitals, and Department of Plastic and Reconstructive Surgery at Nasser Institute for Research and Treatment in the period from June 2020 to June 2021. Results: 20, consecutive, exclusively males, patients, aged from 3 to 57 years old (Mean 28 ± 12 SD years), had a “Free-Style, Perforator-Plus Flap” reconstructive surgery, to cover defects presented at lower Leg two-thirds (75% of cases), Tendo-Achilles (10%) and Ankle (15%) regions. Flap complications were encountered in 4 cases (20%): 2 cases (10%) had distal congestion, the other 2 cases had distal ischemia, which one of them developed full-thickness distal loss. The final recipient outcome “Defect Coverage” was achieved in all cases (100%). Conclusion: The Free-Style, Perforator-Plus Flap is reliable with relative efficiency, versatile, and has a modest rate of failure and need for secondary surgery. It capable to reconstruct small to relatively large, complex defects (exposed bone or hardware and chronic osteomyelitis) in the distal Leg two-thirds, Tendo-Achilles, and Ankle regions.

Knowledge and Self-Care Practices among Psoriatic Patients in Benha City

Background: Psoriasis is a common, chronic, non-communicable skin disease, with no clear cause or cure. The negative impact of this condition on people’s lives can be immense. Psoriasis affects people of all ages, and in all countries. The reported prevalence of psoriasis in countries ranges between 0.09% and 11.43%, making psoriasis a serious global problem with at least 100 million individuals affected worldwide. Psoriasis has an unpredictable course of symptoms, a number of external triggers and significant comorbidities, including arthritis, cardiovascular diseases, metabolic syndrome, inflammatory bowel disease and depression. The study aimed to assess knowledge and self-care practices among psoriatic patients. Research design: A descriptive research design was utilized to conduct this study. Setting: The study was conducted at Dermatology Hospital out-patient clinics and Dermatology Out-Patient Clinics of Benha University Hospital in Benha City. Sample: A convenient sample was selected from the above mentioned setting; it included 30 psoriatic patients. Tools: Two main tools. Tool I: A structured interviewing questionnairePart I: A) Socio-demographic characteristic of the psoriatic patients, B) Past medical history of the psoriatic patient, c) Current medical history. Part II: Psoriasis Knowledge Questionnaire (PKQ). Tool II: The patients' self-care practices toward psoriasis. Results: 40% of studied patients aged more than 50 years old, 73,3% of studied patients were males, 56.7% of psoriatic patients had poor total knowledge, While 23.3%of them had a good total knowledge score and 73.3% of studied patients had total unsatisfactory self-care practices score toward psoriasis. Conclusion: there was a positive correlation between the studied patients' total knowledge score and their total self-care practices score regarding psoriasis. Recommendation: Health educational program about psoriasis should be developed and implemented at outpatient clinics to improve patients' knowledge and self-care practices regarding psoriasis.

The association between allergic rhinitis and Polymorphism of Toll like receptors 2 &amp; 4 genes

Background: Allergic rhinitis is atopic disorder, 10% to 25% of the population worldwide are suffering from it, The prevalence is increasing during the last 10 years. Objectives: To study the relationship among polymorphism of single nucleotide in TLR2 and TLR4 genes and the risk of allergic rhinitis disease. Methodology: This study was done on 60 patients suffering from allergic rhinitis and 30 healthy subjects as a control group from April 2019 to March 2020. The patients were collected from Otorhinolaryngology Department of Benha University Hospital. Test of Skin prick (SPT) was done to assess atopic state. Blood samples were collected to detect TLR gene polymorphism by Polymerase chain reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). Results: The genotypic frequencies of TLR2 Arg753Gln showed increased frequency of the homozygous (GG) genotype among the controls (80%) more than the allergic rhinitis patients (30%). The heterozygous (AG) genotype was increased among the allergic rhinitis patients (62.5%) more than in the healthy group (15%) with OR =9.4, 95% CI (2.4-37.7) and significant P-value. Also, the homozygous mutant (AA) genotype has more trend in the patients (7.5%) than in the control subjects (5%), with OR = 0. 6, 95% CI (0.1-6.7) and non-significant P-value. The genotypic frequencies Statistical data in TLR4 Asp299Gly revealed that the homozygous (AA) genotype has more frequency in the controls (70%) than the allergic rhinitis patients (20%). The heterozygous (AG) genotype was more prevalent among the allergic rhinitis patients (65%) than the controls (30%) with OR =4.3, 95% CI (1.4-13.8) and significant P-value. Conclusion: GG genotype of TLR2 and AA genotype of TLR4 are least affected by allergic rhinitis disease and the major allele in both gene is protective against the disease.

The role of miRNA-196a2 genotypes in the susceptibility of acute lymphoblastic leukemia in Egyptian children

BackgroundDifferent types of miRNA were discovered to have a big role now in many diseases and cancer. ObjectivesThis study assessed the association between the miRNA-196a2 (rs 11614913) polymorphism and acute lymphoblastic leukemia (ALL) in children. DesignRetrospective case-control study. SettingsThis study was done in Benha University Hospital Pediatric Department & Benha Specialist Hospital for Children from May 2019 to February 2020. Subjects and methodsBlood DNA samples from cases and control children were studied for the miRNA-196a2 (rs11614913) polymorphism using Polymerase Chain Reaction-Restriction Fragment-Length Polymorphism (PCR-RFLP) approach. Sample size100 childhood ALL patients and 60 apparently healthy children as control were recruited in our study. ResultsThe frequency of miRNA-196a2 (rs 11614913) C allele was 56.7% in control compared to 54% in cases. In addition there was no significant association between CC or TT genotypes and susceptibility of pediatric acute lymphoblastic leukemia (P = 0.74 and 0.36). There was statistically highly significant increase in TT genotype in males compared to females and significant increase in mean of LDH and ESR in TT genotype compared to CC genotype. ConclusionWe concluded there was no association between miRNA-196a2 genotypes and pediatric acute lymphoblastic leukemia in Egypt. LimitationsSmall patient sample size.

Effectiveness of Comprehensive Intervention Package on pregnant Women's Perception regarding Selected Aspects of Safe Motherhood

Background: knowledge and attitude about safe motherhood practices could help not only to reduce pregnancy related health risks but also helps in improving maternal and child health. Aim: of this research was to evaluate the effectiveness of comprehensive intervention package on pregnant women's perception regarding selected aspects of safe motherhood. Design: A quasi- experimental design was utilized. Sample: A purposive sample of (154 pregnant women) (One Group Pre-test Post-test design). Setting: The research was carried out in obstetrics & gynecology outpatient clinic at Benha university hospital. Tools: Data were collected through three main tools: A self-administered questionnaire to assess women's socio-demographic characteristics and obstetrical history, maternal knowledge questionnaire, modified likert scale to assess women's attitude. Results: showed that the mean age of studied sample 22.9±6.87 years. There was improvement with a highly statistically significant difference observed in women's knowledge and attitude regarding all aspect of safe motherhood at post-intervention phase compared with pre- intervention phase (p < 0.001). A highly statistically significant positive correlation between total knowledge and total attitude regarding safe motherhood at pre-intervention phase (P≤ 0.001). While, there was a significant positive correlation between total knowledge and total attitude regarding safe motherhood at post-intervention phase (P≤ 0.05). Conclusion: The research concluded that research hypothesis is supported and the implementation of comprehensive intervention package succeeded in and had a considerable improvement in the knowledge and attitude regarding different aspects of safe motherhood among pregnant women. Recommendation: Applying educational intervention to improve women's perception about safe motherhood practices in different maternity health services to prevent further maternal and fetal mortality and morbidity

Effect of young rural women’s general characteristics on their knowledge and compliance with healthy practices during postpartum period

The aim of this study was to explore effect of young rural women’s general characteristics on their knowledge and compliance with healthy practices during postpartum period Research design: A descriptive study design was utilized. Setting: This study was conducted in Obstetrics &Gynecological outpatient clinic at Benha University Hospital. Sample: A simple random sample included 183 postpartum women Tools of data collection 1) a structured interviewing sheet to collect data about general characteristics and knowledge of women regarding healthy practices during postpartum period 2) self-reported measures to assess women's compliance with healthy practices during postpartum period .Results: 43.17% of studied women aged from 23 to 25 years with the mean age 22.248 ±1.794. Also 89.86% of studied women had incorrect total knowledge score about postpartum care, 99.28% of them not compliance with health practices about postpartum care. Conclusion: it can be concluded that around the most of studied women had poor knowledge about postpartum care and the majority of them not compliance with health practices about postpartum care. Reveals that, statistically significant relation between general characteristics of young rural women, total knowledge and total practices score toward postpartum care. Also there was a positive highly significant relation between total knowledge score and total practices score. Recommendation: Designing and implementing guidelines, brochure among pregnant women during third trimester and women during postpartum period to raising awareness about the care during postpartum period. Implementing counseling session to enhance women to seek antenatal, labour and postpartum health services.

Effect of Educational Program about Talent Management for Nursing Managers on Their Job Affiliation and Organizational Excellence

Background: Talent management has been on the agenda of many health care organizations because of the belief in its importance in achieving organizational excellence and make their personnel more affiliated to achieve organizational objectives. Aim: The study aims to evaluate the effect of educational program about talent management for nursing managers on their job affiliation and organizational excellence. Research Design: A quasi experimental research design was utilized to carry out the current study. Setting: The study was conducted in all (48) units at Benha University Hospital Qaluobia Governate, Egypt. Subjects: all (52) nursing managers that include (1) Nursing Director, (3) Supervisors, and (48) head nurses. Tools: Four tools were used in this study; First: Talent Management Knowledge Questionnaire, Second: Talent Management activities Questionnaire, Third: Job Affiliation Questionnaire and the fourth tool: Organizational Excellence Questionnaire. Results: The study findings revealed that there were highly statistical significant improvement in the nursing managers' levels of talent management knowledge and activities, job affiliation and organizational excellence after intervention both immediately post and follow up the program. Conclusion: The study concluded that there were statistically significant positive correlation among nurse managers' talent management knowledge and activities scores with their job affiliation and organizational excellence scores. Recommendation: Establishing bases for recruitment and selection in hospital that rely on the criteria of talents acquisition.