Beneficial Method Research Articles

The effect of piperine and curcumin on the calmodulin gene of Echinococcus granulosus protoscolices in vitro

Cystic echinococcosis (CE) has been defined as an illness that results from the larval Echinococcus granulosus stage. Treating cystic echinococcosis is fundamentally dependent upon using Albendazole that may typically result in negative side effects, which is why, more sufficient options of treatment being necessary. The re-purposing of the drugs has been considered as a beneficial method to advance the drug development. In vitro proto-scolicidal effect of the piperine and curcumin have been assessed in E. granulosus and expression of calmodulin (CaM) genes, both of them were linked to the cellular signaling activities. Based on the results, curcumin and piperine’s have dose-dependent proto-scolicidal effects to achieve the optimal efficacy that the isolated piperine 20mg/k and 2g/k curcumin showed significant anthelminthic activity compared to the standard anthelminthic drug enhancing the bioavailability of curcumin. Calmodulin, as a dynamic Ca 2+ sensor, mediates various activities of the cellular signaling from E. granulosus will be possibly involved in a significant biological function.

Reviewing the Physiology of Cutaneous Wound Healing and Evaluating the Effect of Exercise on It: A Narrative Review Article

Context: The skin is the most important organ of the body, and maintaining its integrity is important for health. Severe skin damage is life-threatening, and wound healing restores its integrity. One of the main health problems is impaired cutaneous wound healing. According to the importance of wound healing and the fact that unrepaired skin decreases the quality of life, many studies have investigated the effect of some natural and chemical substances on the length and quality of wound healing to find beneficial interventions for rapid and economical treatment. Objectives: This review was conducted to describe the physiology of cutaneous wound healing and some positive and negative factors affecting it with a focus on exercise. Evidence Acquisition: An electronic search without any time limitation was performed on the PubMed, Google Scholar, and Web of Science databases. The keywords were ‘wound’, ‘healing’, and ‘exercise’. Finally, according to the similarities or differences between the results and the relationship with the subject, 53 papers were selected and reviewed. Results: Wound healing is a complex physiological process with four overlapping processes. It seems that disturbance in the inflammatory phase of wound healing is the main factor in the impairment of healing. Traditionally, many chemical and herbal medicines and compounds have been used to speed up wound recovery due to their anti-inflammatory and antioxidative properties. Many studies have evaluated the effect of exercise, as complementary medicine, on wound healing, and they have examined the effect of different protocols of exercise on the speed of wound healing. According to the results of these studies, aerobic exercise, due to its anti-inflammatory and antioxidative effects, is a beneficial method in shortening the length of healing, especially in aged, obese, and diabetic individuals. Conclusions: Exercise as a low-cost intervention is a good strategy in the treatment of impaired and chronic wounds.

On the possibility to process copper-molybdenum ore using a combined flotation reagent

The article presents the results of laboratory studies on ore flotation of copper-molybdenum deposits in the East Kazakhstan region of Kazakhstan using a combined reagent. It is required to use new beneficiation methods and flotation reagents to increase the efficiency of flotation of ore minerals to improve the processing of finely disseminated ores. The problem can be solved by using a combination of different collectors. The objective of the research is to increase the recovery of copper and molybdenum during flotation of copper-molybdenum ore using a combined reagent. The studied ore sample contains 0.42% copper; 0.009% molybdenum. A combination of sodium butyl xanthate, TS-100 thionocarbamate, and reaflot in a ratio, in %: 15: 3: 1, was used as a combined flotation reagent. The combined flotation reagent was preliminarily passed through an ultrasonic homogenizer JY96-IIN to obtain a reagent microemulsion before flotation. The optimum dispersion time for the combined flotation reagent is 60 seconds. At the same time, 99.4% are microemulsion particles with a particle size of fewer than 3.7 microns. The use of a combined reagent microemulsion increases the extraction of copper into the copper-molybdenum concentrate by 3.69%, and the extraction of molybdenum by 6.05%. The copper content in the copper-molybdenum concentrate increases by 1.26%. The copper content in the flotation tailings decreases from 0.07 to 0.056%. The consumption of the combined reagent is reduced by 15% in comparison with the basic butyl xanthate.

Is Less Invasive Surfactant Administration a Beneficial Method for Late Preterm Infants?

Late preterm infants (LPIs) have increased steadily in all newborns delivery and they are the largest patient group requiring admission to the neonatal intensive care unit. Surfactant treatment is frequently used in LPIs in case of respiratory distress, but the procedure and the timing of surfactant administration are not well-known. We aimed to evaluate the effect of surfactant administration techniques on pulmonary outcomes in LPIs with respiratory distress. In this retrospective study, we compared the effects of the less invasive surfactant administration (LISA) technique and conventional treatment on respiratory and other morbidities in LPIs who have respiratory difficulties. We named these two groups as the LISA group and the conventional group (CG). Comparison of the mechanical ventilation (MV) rates between the groups was the primary outcome of our study. There were 25 LPIs in each group. The duration of nasal continuous positive airway pressure (CPAP) and oxygenation were similar in both groups. The rate of MV and the duration of MV (P=0.004 and P=0.02) were lower in the LISA group. Also, the need for more than 1 dose of surfactant was higher in the MV requiring group, although it was not statistically significant between the groups (P=0.21). Using the LISA technique for surfactant instillation reduces any MV requirement. LISA is a very useful and reliable technique in experienced hands in LPIs as in very preterm infants.

Mechanochemical synthesis of eco-friendly fertilizer from eggshell (calcite) and KH2PO4

The present article, based on reverse logistic, provides an environmentally beneficial and cost-effective method of producing calcium phosphate bioceramics (potassium calcium phosphates) aimed for soil conditioning, by a free-solvent mechanochemical process between eggshell waste and KH2PO4. The K3CaH(PO4)2 and possibly CaKPO4 phases formed provide a better nutrient management of P, K and Ca, when applied in soil system the material first release K and form hydroxyapatite and important P and Ca bioavailable source at pH ∼ 5, which comprises a large part of many countries soils.

A few words about the arthrodesis operation

The operation of arthrodesis, or artificial ankylosis of the joint, first performed by Albert in 1878, is one of the most beneficial orthopedic methods of treatment in cases of complete paralysis of all muscles moving this joint and in cases of ankylosis in a functionally disadvantageous position of the joint, when a quick recovery of the patient's ability to work is required if it is impossible, for one reason or another, to use his orthopedic devices.

Tin reduction from fluorine doped tin oxide for silicon nanowire-based solar energy harvesting and storage.

Hydrogen plasma reduction of fluorine doped tin oxide is a beneficial method to form tin nanodroplets on the sample surface directly in the plasma-enhanced chemical vapor deposition reactor. The formation of catalyst droplets is a crucial initial step for vapor-liquid-solid growth of silicon nanowires for radial junction solar cells and solar fuel cell technology. We present an original optical model which allows us to trace the formation process on fluorine doped tin oxide on soda-lime glass substrate from the in situ data and is in a good agreement with the spectroscopic ellipsometry data measured before and during the reduction process. The model reproduces well the phase shift introduced by a transition double layer in fluorine doped tin oxide which acts as a barrier against the sodium diffusion. Furthermore, we study the process of tin reduction from fluorine doped tin oxide in a real time and compare estimated amount of produced metallic tin with images from scanning electron microscopy.The proposed approach is very important for in situ real-time monitoring of the one-pump-down fabrication process used to grow nanowires and form radial junction devices.

Influence of Drying Methods and Vacuum Impregnation on Selected Quality Factors of Dried Sweet Potato

A comparative study was conducted on the effect of vacuum impregnation and drying methods on the production of dried sweet potatoes with high bioactivity. The present study determined the quality and physicochemical properties of dried sweet potato depending on the used impregnating solutions. Sweet potatoes were pretreated in freshly squeezed onion (O) and kale (K) juice, onion and kale (OK) mixture (1:1), and sodium chloride solution. Vacuum impregnation (VI) was carried out under reduced pressure (6 kPa) for 2 min, after which the impregnating solution was dispensed and maintained under vacuum for 4 min. Sweet potato slices were dried using vacuum drying (VD) and freeze drying (FD) methods. Higher content of polyphenols, carotenoids, and chlorophyll, as well as increased antioxidant capacity and higher VOC profile, were recorded for the dried products obtained using the sublimation method. The use of vacuum impregnation reduced the hardness of the products and other textural characteristics, such as cohesiveness, springiness, and gumminess. Furthermore, we found that vacuum impregnation pretreatment was a beneficial method for improving the characteristics of dried vegetables. The highest content of phenolics, carotenoids, and chlorophylls in dried sweet potatoes were recorded when samples were impregnated with onion and kale juice. For the fresh sweet potato, the highest contribution in VOC composition had phenylacetaldehyde (44.90%), (E)-2-octen-1-al (9.43%), and benzaldehyde (8.18%), respectively. The interesting content of VOC profile compounds in dried sweet potatoes was recorded when samples were impregnated with kale juice.

Separation Efficiency of Different Methods to Treatment of a Low-Grade Iron Ore

In the present study, characterization and beneficiation tests were performed on an iron ore sample to evaluation of separation efficiency (SE) of different methods. Results showed that the decrease in feed size fraction increases the SE irrespective to beneficiation method. It was determined from the liberation analyses that the increase in SE values ​​at finer size fractions is related with higher liberation. Calculated SE values revealed that operational parameters significantly affect the SE of all methods and the net forces acting on particles play an important role on SE of different size fractions. Mean SE of different size fractions showed that separation efficiencies of gravity concentration and magnetic separation takes similar values above 1 mm, however, SE of magnetic separation is significantly higher than gravity concentration below 1 mm for studied sample. For low grade ores, it is very crucial to develop a flow sheet to achieve the optimum grade and recovery while decreasing the cost likely by using optimum method. Therefore, SE calculations used in this research can be used as a basic method to compare the efficiency of different beneficiation methods. SE method has advantages because they are fast methods for the efficiency evaluation by using experimental results.

Experimental Study of the Effect of Lyophilized Platelet Growth Factors (LPGFs) on Healing of Critical Size Defect in Craniofacial Bone

Background: The maxillofacial trauma and their complications represent a great socio-economic concern for the Egyptian health system. There are multiple reconstructive options are available for reconstructing the critical size defects in craniomaxillofacial field. The reconstruction of the critical sized defects by autografts is considered the golden standard. They offer minimum immunological rejection, complete histocompatibility and can provide the best osteoinductive, osteoconductive and osteogenicproperties. Cell therapy and its applications showed great advance in reconstructive surgery in the last years. Growth factors derived from platelet rich plasma (PRP) can contribute to tissue regeneration in allogenic bone graft, by assisting cell migration, proliferation, differentiation and extra cellular matrix synthesis. Objective: To study the effect of human lyophilized GFs on healing of critical size bone defect in craniofacial bone of animal. Materials and Methods: This study was conducted between October 2016 and October 2018. It was conducted at the Medical Research Center associated with Ain Shams Faculty of Medicine and approved from the Research Ethics Committee (REC) of Faculty of Medicine, Ain Shams University (No: FMASU 1969/2014). Using 30 albino rats divided into 3 groups. Results: The results obtained in this study revealed a statistically significant bone healing after reconstruction of critical size calvarial bone defects by Lyophilized platelet growth factors (LPDGF) seeded on allogenic Demineralized bone matrix (DBM). In conclusion, this study presents a beneficial method for reconstruction of critical size calvarial bone defects by an already made non-immunogenic new tissue regenerate.Conclusion: This study advocate the use of DBM with LPDGF as a reconstructive tool for bone regeneration. But further clinical studies are needed to evaluate its rule in the unfavorable general and local conditions.

EVALUATION EFFECT OF APPLICATION METHODS OF DIFFERENT SOURCES OF HUMIC SUBSTANCES ON POTATOES PLANT GROWTH, PRODUCTIVITY AND QUALITY IN NEWLY RECLAIMED SANDY SOIL UNDER DIFFERENT LEVELS OF MINERAL FERTILIZERS

The present work was conducted to: evaluate the effect of application methods of CT, HA and FA individually or in combination without and with recommended mineral fertilizers doses (RMFD) (50 and 100%), on potato growth and their yields. To achieve these objectives, a field experiment during winter seasons of 2019 was conducted at El Nagah Village, El-Tahrir Region, El Beheira Governorate, Egypt (Latitude 30o.40´N- Longitude 30o.33´E) (represented newly reclaimed sandy soil). The layout of the experiment was a split- plot design, with the main plots arranged in a randomized complete blocks design with three replicates. Potatoes (Solanum tuberosum L) plants cultivar Spunta, as a tuber crop. Three application methods of the used organic amendments were applying. These methods were: soil application (through drip irrigation Drip), foliar spray Spray and the alternative between them Spray/Drip. The application methods of Spray/Drip was carried out by applying half amount of each organic amendments applying as soil application and the other 50% was applied as foliar spray). This study including the treatments of control (without any applications of organic amendments treatment). The used CT was added at a rate of 200 L fed-1. FA and HA were added at a rate of 6 and 10 Kg fed-1. respectively. The used mineral fertilizers (NPK) were applied at two rates (50 and 100% of recommended dose for the potato plants. After 40 and 65 days from sowing, dry matter yields (DMY) of the growing plants (shoots) and at harvesting, tuber yield per fed. feddan=4200 m2), as well as quality traits their elemental composition, mainly contents of nitrogen, phosphorus, potassium were determined. The obtained results indicated that, DMY (shoots and tuber) of potato plants received the combined application of CT+ HA+ FA were the highest values under all application methods compared to their individual application, under both levels of mineral fertilization, at 40 and 65 days after sowing for shoots as well as at harvesting for tubers. The maximum values of N, P and K contents of potato shoot at 40 and 65 days after sowing and in tubers were obtained from double application (Spraying/Drip (method treatments of the in-combination treatments of organic amendments under both levels of recommended mineral fertilization. Accordingly, the duple application Spray/Drip methods of organic amendments, considered a more beneficial application methods in the cultivation of potato plants (Spunta cultivar) in newly reclaimed sandy soils due to it resulted in a high tuber yield, quality and reducing the environmental pollution as a result from reducing the additions of the mineral fertilizer with the in combination organic amendments.

Effects of plasma‐activated water and heat moisture treatment on the properties of wheat flour and dough

SummaryPlasma‐activated water (PAW) production and use is an emerging technology for enhancing product safety, extending shelf‐life and quality retention, and promoting sustainable processing. At present, it has generated considerable attention for applications to starch and flour modification. This work presents an innovative approach to wheat flour (WF) modification using PAW and heat‐moisture treatment (HMT), and compares this approach with distilled water (DW) treatment. As expected, PAW and HMT promoted flour granule clustering, increasing particle size. These treatments accelerated molecular interactions between wheat starch and non‐starch components (e.g. proteins and lipids), which eventually increased resistant starch (RS) content. Addition of modified flour (30 g) to WF positively affected its rheological properties, and closely bound water content of the dough. The gluten protein network structure in the dough suffered varying degrees of damage. In conclusion, our results showed that PAW and HMT may provide a novel beneficial method for modifying wheat flour during food processing to obtain viscoelastic wheat flour products with nutritional functions.

Anaphylaxis in Obstetrics—Double the Trouble

(Anaesthesia. 2020;75:1424–1427) Anaphylaxis in obstetrics, a rare but life-threatening event, can be expected for an individual anesthetist to witness once every 7 years. As the infrequency coupled with difficulties and challenges of resuscitation may heighten anxieties with such events, investigations such as the pan-European study provide further insight into beneficial management methods.

Fermentation with edible Rhizopus strains as a beneficial alternative method in wheat germ cake processing

Wheat germ cake (WGC) is a nutritionally valuable by-product of oil production from wheat germ, of broad but not yet fully used potential for food applications. Solid-state fermentation with Rhizopus oligosporus and R. oryzae was tested as a new method of WGC bioprocessing aimed to obtain compact products overgrown with mycelium, characterised by a favourable composition.The best results were obtained after 96-h fermentation. The fermented material contained, on average, 42% more peptides, had 30% higher ABTS˙+ scavenging activity, and 100% higher ˙OH -scavenging activity than the raw substrate. The fermented WGC had, on average, 720 μg/g DM soluble phenolic acids, with a significant share of protocatechuic acid (69%). The fungal activity increased the levels of free protocatechuic acid and p-hydroxybenzoic acid. The fermented WGC was a good source of high-quality protein (28 g/100 g DM) rich in Lys (6.9 g/100 g protein), Phe + Tyr (7.9 g/100g protein) and Leu (7.3 g/100 g protein). The products also contained around 14.5 g/100 g DM of dietary fibre with 60:40 insoluble to soluble fraction ratio.Solid-state fermentation can be considered a new method for increasing the nutritional and bioactive value of WGC, thus extending the possibilities of its application for the food industry.

Equitable resource allocation for municipal safety: A data envelopment analysis

To improve local roadway safety, the diverse nature of municipalities must be considered given their differing needs associated with their unique population characteristics and physical environments. Yet, these differences are not accounted for in the current funding frameworks that support local highway departments. This paper explores the factors that impede the ability of municipalities to efficiently and equitably distribute highway funding to improve local road safety. Data envelopment analysis is conducted by fusing municipal highway staff data, municipal highway expenditure data, crash data, geographic data, and demographic data. Among other findings, this study concludes that non-white and rural regions require more financial support to equitably improve safety. Further, data envelopment analysis is demonstrated to be a beneficial method to consider equity disparities at a local level. The results suggest where local highway resources should be invested to efficiently and equitably improve local roadway safety.

Resisted Sprint Training in Youth: The Effectiveness of Backward vs. Forward Sled Towing on Speed, Jumping, and Leg Compliance Measures in High-School Athletes.

Uthoff, A, Oliver, J, Cronin, J, Winwood, P, Harrison, C, and Lee, JE. Resisted sprint training in youth: the effectiveness of backward vs. forward sled towing on speed, jumping, and leg compliance measures in high-school athletes. J Strength Cond Res 35(8): 2205-2212, 2021-Resisted sprinting (RS) is a popular training method used to enhance sprinting performance in youth. However, research has only explored the effects of forward RS (FRS) training. We examined the effects of FRS and backward RS (BRS) and compared these with a traditional physical education curriculum (CON). One hundred fifteen boys (age 13-15 years) were matched for maturity and allocated to either an FRS (n = 34), BRS (n = 46), or CON (n = 35) group. Training groups towed progressively overloaded sleds (20-55% body mass) 2 d·wk-1 for 8 weeks. Pre-training and post-training data were collected for sprinting times over 10 and 20 m, countermovement jump (CMJ) height, and leg stiffness (KN). Performance remained unchanged for the CON group (all p > 0.05), whereas all variables significantly improved (p < 0.05) after BRS, and all but 10-m performance improved after FRS. Compared with the CON, BRS and FRS significantly (p > 0.05) improved CMJ (Effect size [ES] = 0.67 and 0.38) and KN (ES = 0.94 and 0.69), respectively. No differences were found between training groups. The probabilities of improving sprinting performance after BRS (∼70%) were on average ∼10 and ∼8% better than the FRS and CON groups, respectively. The BRS and FRS showed similar probabilities of improving CMJ (75 and 79%) and KN (80 and 81%), respectively, over the CON group. It seems that BRS may be a means to improve sprint performance, and regardless of direction, RS seems to be a beneficial method for improving jumping height and leg stiffness in youth male athletes.

Segregation and mixing behavior of geldart D binary particles in pulsed gas-solid fluidized bed

Gas-solid fluidized bed is an effective dry method for beneficiation of −6mm fine coal, belonging to Geldart D particle. Due to the density difference of concentrates and gangue in the raw coal, the bed can remove gangue through segregation of binary particles. The core problem is how to reduce the bubble coalescence and improve segregation degree in the bed. In this study, glass beads and plastic beads were selected to simulate high-density and low-density particles in pulsed gas-solid bed (PGFB). And different pulsation frequencies (f = 0–7 Hz) and gas velocities (N = 1.1–1.7) were selected in this work. The results showed that gas velocity and pulsation frequency played important role on particle segregation and mixing behavior. The segregation index reached the maximum value at pulsation frequency f = 3.49 Hz and gas velocity N = 1.3 when h = 80 mm, indicating pulsed gas-solid fluidized bed can effectively separate particles of different densities. With the increase of bed height, the standard deviation of separation index decreases, and the optimal frequency moves to the low frequency region. This work provides guidance for the study of segregation and mixing behavior of Geldart D binary particles in pulsed fluidized bed.

Study on the Coexistence of Offshore Wind Farms and Cage Culture

In this study, a hydrodynamic model was used that includes the effects of wave–current interactions to simulate the wave and current patterns before and after offshore wind turbine installation in western Taiwan. By simulating the waves and currents after the offshore wind turbine was established, the waves and currents caused by the wind turbine were seen to have a limited range of influence, which is probably within an area about four to five times the size of the diameter (12–15 m) of the foundation structure. Overall, the analysis of the simulation results of the wave and current patterns after the offshore wind turbines were established shows that the underwater foundation only affected the local area near the pile structure. The wind farm (code E) of the research case can be equipped with about 720 cage cultures; if this is extended to other wind farms in the western sea area, it should be possible to produce economic-scale farming operations such as offshore wind power and fisheries. However, this study did not consider the future operation of the entire offshore wind farm. If the operation and maintenance of offshore wind farms are not affected, and if the consent of the developer is obtained, it should be possible to use this method to provide economically large-scale farming areas as a mutually beneficial method for offshore wind power generation and fisheries.

Effect of ultraviolet-C light on the environmental bacterial bioburden in various veterinary facilities.

To determine the effect of a mobile UV-C disinfection device on the environmental bacterial bioburden in veterinary facilities. 40 swab samples of surfaces from the operating theaters of 3 veterinary hospitals and 1 necropsy laboratory. Various surfaces were swabbed, and collected material was eluted from the swabs in PBSS. Then, an aliquot of the sample fluid was processed with a bacteria-specific rapid metabolic assay to quantify bacterial bioburden. Each site was then treated with UV-C light with an automated disinfection device for approximately 45 minutes. The same surfaces were swabbed following UV-C treatment, and bioburden was quantified. The bioburden at additional time points, including after a second UV-C treatment, was determined for the small animal operating theater. All surfaces at all sites had a persistent viable bacterial population following manual cleaning. Disinfection with UV-C achieved a mean bioburden reduction of 94% (SD, 5.2%; range, 91% to 95%) for all surfaces, compared with manual disinfection alone. Repeated UV-C treatment of the small animal operating theater reduced mean bioburden by 99% (SD, 0.8%), including no detectable bacteria on 4 of 10 surfaces. Disinfection with UV-C light may be a beneficial adjunct method for terminal disinfection of veterinary operating theaters to reduce environmental bioburden. (Am J Vet Res 2021;82:582-588).

Stature Estimation from Dry Bone and Radiographic Clavicular Measurements in A Thai Population

Stature is one of the main biological features which can be used to classify unidentified skeletal deceased. Also, precise population data is crucial for forensic anthropology frameworks. Nonetheless, the studies concerning this subject in Thailand are limited and regularly focus on long bones. This study attempts to establish stature estimation equations from clavicular dry bone and radiographic measurements. Both sides of the clavicular bones are separated from 25 female and 112 male deceased in an autopsy room situated in Bangkok, Thailand. Twelve variables of each side of the clavicle are measured. The study outcomes show that stature can be estimated by applying 3 variables in a stepwise regression analysis model in unidentified sex remains, with R2 = 0.49 and standard error of estimation (SEE) 5.238 cm. Moreover, the height of the sternal end of clavicle bones can be used to estimate stature in cases of fragmented clavicles recovered from crime scenes with R2 = 0.238 and SEE 6.353 cm. Maximum length shows the best correlation and model fit with stature (R = 0.562, R2 = 0.316 and SEE 6.020 cm) from radiographic measurements. Therefore, this study presents a complementary, beneficial method for forensic anthropologists to create biological profiles of unidentified skeletal remains in cases where the long bones are not obtainable. Moreover, stature estimation from radiographic measurements can be applied in cases of partial skeletonisation.