ABSTRACT Juvenile delinquency, where young people engage in criminal behavior, is a serious concern for society due to high arrest rates among minors. Delinquent behavior is a serious concern due to its devastating effect on the well-being of society. The relationship between genetics and violent behavior is complex and not fully understood. This study aims to investigate the correlation between specific genetic traits, particularly CRHR1 and FKBP5 genes, and sociodemographic characteristics in the context of their age, gender, socioeconomic status, and crime history of delinquent behavior in adolescents. The study was designed as a single-center hospital-based case–control study involving 45 adolescents for each study group: control and those showing delinquent behavior, case group. Findings revealed an abnormal CRHR1 expression in male teenagers is a strong indicator and presents the risk for violent and delinquent behavior. Understanding specific genetic markers, like abnormal CRHR1 expression, helps target assessments and interventions. Additionally, recognizing sociodemographic factors associated with delinquency allows for a more comprehensive approach, considering the various influences on adolescent behavior. This study provides important insights to address and reduce the complex issue of juvenile delinquency.