Behavioral Inhibition Research Articles

Impaired inhibitory control when processing real but not cartoon emotional faces in autistic children: Evidence from an event-related potential study.

Impaired socioemotional functioning characterizes autistic children, but does weak inhibition control underlie their socioemotional difficulty? This study addressed this question by examining whether and, if so, how inhibition control is affected by face realism and emotional valence in school-age autistic and neurotypical children. Fifty-two autistic and 52 age-matched neurotypical controls aged 10-12 years completed real and cartoon emotional face Go/Nogo tasks while event-related potentials (ERPs) were recorded. The analyses of inhibition-emotion components (i.e., N2, P3, and LPP) and a face-specific N170 revealed that autistic children elicited greater N2 while inhibiting Nogo trials and greater P3/LPP and late LPP for real but not cartoon emotional faces. Moreover, autistic children exhibited a reduced N170 to real face emotions only. Furthermore, correlation results showed that better behavioral inhibition and emotion recognition in autistic children were associated with a reduced N170. These findings suggest that neural mechanisms of inhibitory control in autistic children are less efficient and more disrupted during real face processing, which may affect their age-appropriate socio-emotional development.

Synthesis of 7,8-dihydroxy-4-phenylbenzo[g]coumarins as potential multitarget anti-skin-aging candidates

Skin aging is a gradual, spontaneous, slow-processing, and natural phenomenon that induces a negative impact on the skin's function and structure. Numerous cosmoceutical products have been studied for their ability to prevent skin aging. However, only one published study looked into these coumarin-related traits. This research gap stimulated the initiation of the present work, in which six 4-phenyldihydroxybenzocoumarins were synthesized starting from 2,3,6-triaminonaphthalene. The latter was transformed into a diazonium salt product that undergoes a Sandmeyer reaction, forming 2,3,6-trihydroxynaphthalene. This multihydroxylated compound is coupled with various ethyl benzoylacetate derivatives to yield the target compounds coded YR1-YR6. By analyzing the FTIR, 1HNMR , 13CNMR , and HRMS spectra, the molecular structures of the synthesized coumarins were confirmed. The anti-skin-aging potential was evaluated by following the inhibitory properties of these compounds against four skin aging-related enzymes, which are tyrosinase, elastase, collagenase, and hyaluronidase. Also, the inhibitory behavior profiles were defined by plotting Lineweaver-Burk diagrams. To detect whether they are normal-skin biocompatible, the compounds under investigation were tested using a human skin keratinocyte line. The results showed that the synthesized coumarins demonstrated outperforming inhibitory properties against the test four enzymes exceeding those of references used. Also, the inhibitory behaviors of the synthesized coumarins were collectively detected as competitive inhibitors against enzymes under study. Regarding the skin biocompatibility, these compounds showed excellent biosafety profiles toward the keratinocytes studied. Given the results, the general framework of the synthesized coumarins, 7,8-dihydroxy-4-phenylbenzo[g]coumarin, is responsible for the superior anti-skin-aging effects. On the other hand, the para substitution on the phenyl ring exerts a detected but minor role in these effects. The author concluded that the skeletons of the synthesized coumarins provide insights to develop potential multitarget anti-skin-aging biocompatible candidates. Also, there is a good opportunity for YR1 and YR2 to be directly included in the pre-clinical studies, minimizing the time spent considering them as anti-skin medications.

Translational approaches to the neurobiological study of conditional discrimination and inhibition: Implications for psychiatric disease.

There is a growing number of studies investigating discriminatory fear conditioning and conditioned inhibition of fear to assess safety learning, in addition to extinction of cued fear. Despite all of these paradigms resulting in a reduction in fear expression, there are nuanced differences among them, which could be mediated through distinct behavioral and neural mechanisms. These differences could impact how we approach potential treatment options in clinical disorders with dysregulated fear responses. The objective of this review is to give an overview of the conditional discrimination and inhibition findings reported in both animal models and human neuropsychiatric disorders. Both behavioral and neural findings are reviewed among human and rodent studies that include conditional fear discrimination via conditional stimuli with and without reinforcement (CS+ vs. CS-, respectively) and/or conditional inhibition of fear through assessment of the fear response to a compound CS-/CS+ cue versus CS+. There are several parallels across species in behavioral fear expression as well as neural circuits promoting fear reduction in response to a CS- and/or CS-/CS+ compound cue. Continued and increased efforts to compare similar behavioral fear inhibition paradigms across species are needed to make breakthrough advances in our understanding and treatment approaches to individuals with fear disorders. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Monetary reward enhances response inhibition processes manifested in No-go P3

This study investigated the impact of motivational valence on No-go P3 and N2 by incorporating monetary rewards based on response outcomes. We also investigated how personality differences in terms of the behavioral inhibition system (BIS) and behavioral approach system (BAS) influenced No-go N2 and No-go P3. Twenty-eight participants performed Go/No-go tasks (80 % Go and 20 % No-go) under two conditions. In the reward condition, each correct-rejection trial for the No-go stimulus was rewarded with 10 yen (∼6 cents), whereas in the neutral condition, neither monetary rewards nor punishments were contingent on response outcomes. Individual responsiveness to punishment and rewards was evaluated using the BIS and BAS scales. The error rate was significantly lower in the reward condition than in the neutral condition. P3 amplitude for correct-rejection trials (i.e., preceding erroneous muscular activity on the wrong hand) was larger in the reward condition than in the neutral condition; however, N2 amplitudes did not differ between the two conditions. These results suggest that monetary rewards may enhance motor inhibition control. Individuals with a higher BIS score exhibited a larger No-go N2 for correct-rejection in the neutral condition. We conclude that No-go N2 amplitude is modulated by avoidance motivation.

The coach bots are coming: exploring global coaches’ attitudes and responses to the threat of AI coaching

ABSTRACT Artificial intelligence (AI) in business coaching, as in other human resource development professional service roles, opens up the possibility of multiple chances, such as cost- and time-effective gains. However, as AI can act autonomously and may surpass human performance, it can both lead to unforeseen risks as well as create a threat for professional service workers, including business coaches. Using a within-subject threat manipulation design, the present research investigated whether business coaches (N = 436; from over 50 different countries) respond to the topic of AI in coaching with heightened threat-related affective states and how this change affects their attitude towards the topic. Expectedly, the topic evoked higher behavioral inhibition and lower behavioral activation threat-related affective states, leading to lower curiosity in and a more negative opinion of AI in coaching. Theoretical and practical implications are addressed to lower the coaches’ threat-related affective states towards AI application in professional services. A hybrid approach between responsible AI and an ethically skilled and professionally trained coach is recommended.

Effects of social inhibition and group relations on altruistic behaviour of children under conditions of reputational threat

ABSTRACT . This study examines the relationship between reputational threat and altruistic behavior in children aged 6-11 and explores how social inhibition and group relationships affect this behavior. Study 1 involved 204 children and found that age and reputational threat influence altruism, with age 8 being a key turning point. Study 2 focused on 130 nine-year-olds and showed that children with low social inhibition engage in more altruistic acts, regardless of reputational threat. Study 3, with 151 participants, analyzed the effects of group dynamics based on left-behind status. Non-left-behind children preferred out-group altruism, while left-behind children showed in-group preference under reputational threat, with no difference in its absence. Left-behind children were generally more altruistic. The findings highlight age 8 as crucial for reputation strategies and suggest that reputational threat, social inhibition, and group dynamics shape altruistic behavior. This research offers insights into the positive qualities of left-behind children, informing their development and education.

Decreased Serum Cocaine- and Amphetamine-Regulated Transcript Level in Internet Gaming Disorder.

Vulnerability to internet gaming disorder (IGD) has increased as internet gaming continues to grow. Cocaine- and amphetamine-regulated transcript (CART) is a hormone that plays a role in reward, anxiety, and stress. The purpose of this study was to identify the role of CART in the pathophysiology of IGD. The serum CART levels were measured by enzyme-linked immunosorbent assay, and the associations of the serum CART level with psychological variables were analyzed in patients with IGD (n=31) and healthy controls (HC) (n=42). The serum CART level was significantly lower in the IGD than HC group. The IGD group scored significantly higher than the HC group on the psychological domains of depression, anxiety, the reward response in the Behavioral Activation System and Behavioral Inhibition System. There were no significant correlations between serum CART level and other psychological variables in the IGD group. Our results indicate that a decrease in the expression of the serum CART level is associated with the vulnerability of developing IGD. This study supports the possibility that CART is a biomarker in the pathophysiology of IGD.

Investigating the role of social inhibition in enduring involvement in online synchronous exercise classes: A use and gratification perspective

With the advancement of communication technology, online synchronous exercise courses become more common in recent years due to their ability to transcend time and space. Based on uses and gratifications theory (U&G), this study proposes a conceptual model for online synchronized exercise classes and examines the relationships among social inhibition, motivation, satisfaction, and continued involvement. After 322 valid questionnaires were collected and analyzed by partial least squares (PLS), this study confirmed the significant positive effects of hedonic, identified, and integrative motivation on online synchronous exercise satisfaction and the significant negative effect of social inhibition on online synchronous exercise satisfaction. Moreover, online synchronous exercise satisfaction has a positive effect on enduring involvement. This study not only contributes by extending the application of U&G theory to dynamic online synchronized exercise and addressing the interaction and pressure of online users in cyberspace but also provides novel marketing strategies for fitness and sports organizations.

Digital consumerism in times of crisis: exploring the shift in online shopping behaviour

PurposeThis research delves into consumer online shopping behaviour during the different phases of the COVID-19 pandemic, utilising the Theory of Planned Behaviour and the Behavioural Inhibition System.Design/methodology/approachA unique and comprehensive repeated cross-sectional methodology was meticulously employed, capturing the nuances of consumer online shopping behaviour across three distinct phases of the pandemic: the initial phase following the outbreak of COVID-19, the transition phase marked by the relaxation of restrictions, and the adaptation phase as society moved towards a new normal. The study involved a sample of 1,155 participants. Structural equation modelling was used to analyse the effects of behavioural attitudes, subjective norms, perceived behavioural control, and the moderating role of pandemic-induced consumer anxiety on online purchase intention.FindingsThe impact of behavioural attitudes on online purchase intentions increased continuously from the initial phase to the adaptation phase. In contrast, the influence of subjective norms on online shopping intentions gradually declined over the same period. During the early stages of the pandemic, consumer anxiety amplified the influence of personal attitudes towards online shopping while diminishing the impact of social pressures on the same behaviour.Originality/valueThis study’s originality lies in its nuanced analysis of how online purchase intentions evolved across different stages of the COVID-19 pandemic, integrating insights from both the Theory of Planned Behaviour and the Behavioural Inhibition System. The study offers a comprehensive understanding of the shifts in consumer behaviour over time. It enables more strategic and proactive marketing tactics in a changing environment.

Parent‐reported problematic lying tendencies and BIS/BAS activity as predictors of children's antisocial lie‐telling

AbstractThe current study examined whether age and parental reports of children's problematic lying, behavioural inhibition system (BIS) activity, and reward responsiveness predicted children's antisocial lie‐telling. Children from mostly middle and upper‐class Canadian families (ages 3–12, M = 6.23, SD = 2.52) participated in a modified Temptation Resistance Paradigm (TRP), where they were given opportunities to tell a self‐protective lie (to conceal a transgression) and an instrumental lie (to obtain a reward). Parents completed measures of their children's problematic lying tendencies, BIS activity, and reward responsiveness. Age and parent‐reported problematic lying and BIS activity were significant predictors of lie‐telling behaviour in the TRP. Instrumental liars were younger than dual liars (those who told both types of lies) and truth‐tellers. Truth‐tellers had lower parent‐reported problematic lying than instrumental and dual liars but not self‐protective liars. Dual liars had lower parent‐reported BIS activity than truth‐tellers; there were no differences among truth‐tellers, self‐protective liars, and instrumental liars. This study contributes to our understanding of the role of temperamental factors in children's lie‐telling propensity and the predictive utility of parent‐reported predictors for children's antisocial lie‐telling propensity. Our findings indicate that parents can identify and potentially address their children's problematic lying using their knowledge about their children's temperamental traits.

Acid corrosion inhibition of mild steel by 8-hydroxyquinoline derivatives: organic synthesis, characterization, chemical, electrochemical investigation and theoretical calculations

In this study, two 8-hydroxyquinoline derivatives, HAPAQ and EAPAQ, were first synthesized, and their molecular structures were confirmed by 1H and 13C NMR. The effects of HAPAQ and EAPAQ on corrosion processes were investigated using weight loss, electrochemical, and theoretical methods. Overall, the data unmistakably demonstrate that the inhibition performance (η %) increases with an increase as HAPAQ and EAPAQ concentrations rise, peaking at 96.08% (HAPAQ) and 94.37% (EAPAQ) at the optimal concentration (10−3 M) for PPD technology. The two 8-hydroxyquinoline derivatives exhibit inhibitory behavior, as seen by the polarization curve impedance tests; however, they demonstrate that adsorption promotes protective action on metal surfaces, creating a geometric blocking effect and a protective coating that impedes metal breakdown. HAPAQ and EAPAQ's inhibitory efficacy may be reduced by the rising temperature. Furthermore, it adheres to Langmuir’s single-layer adsorption isotherm, and the physisorption and chemisorption mechanisms are linked to the corresponding value of the adsorption energy (ΔG ads). Additionally, the MS scanning electron microscope (SEM) has been studied and discussed. The possibility of complex organization between the inhibitor molecules, 8-hydroxyquinoline derivatives (HAPAQ and HAPAQ), and the Fe2+ ions generated during the oxidation process was established by examining the test solutions using UV–visible spectroscopy. Consequently, it is evident from DFT simulations that the surface recovery is dependent on the local reactivity descriptors. The theoretical outcomes derived from DFT are aligned with the findings of the experimental studies.

Lanthanum nanoparticle decorated carbon nanotubes: Facile method of synthesis and studies of their redox stability, cytotoxicity and corrosion inhibition on the magnesium alloy in 3.5 % NaCl environment

Functionalized carbon materials can act as high-temperature coatings and eco-friendly composite materials. We have studied lanthanum-doped carbon nanotube (La-CNT) material redox behavior, cytotoxicity, and corrosion inhibition efficiency. The La-CNT material has been characterized by different techniques to confirm the presence of functional groups. The Fourier transform infrared (FTIR) and Raman studies were performed to investigate the functional groups and carbon defects. Field emission scanning electron microscopy (FESEM) and tunneling electron microscopy (TEM) studies were used to investigate the carbon nanotube microstructure, La nanoparticles were shown to interact with the carbon nanotube surface. X-ray diffraction (XRD) techniques were used to confirm the crystallinity of composite material. Electrochemical methods were used to investigate corrosion inhibition and redox stabilities. After corrosion study on the Mg alloy its microstructure was analyzed to confirm the composite material inhibition efficiency. The composite material showed significant cytotoxicity, and corrosion inhibition efficiency was shown to be 82 % as compared with pristine epoxy-coated Mg alloy.XPS results are suggested that alloy oxide layer formed. The DFT study supported the experimental findings.

Effect of different freezing conditions on ice crystal formation behavior and ice-growth inhibition by cryoprotectants.

The formation of ice crystals will have adverse effects on aquatic products, and the key to ensure the long-term preservation and better quality preservations of the product is to evaluate the intercellular ice crystal formation to find suitable refrigeration conditions and cryoprotectants. The ice crystal formation was successfully captured by using an inverted microscope cryomicroscopic system equipped with a low-temperature stage, the ice crystals formed under different freezing methods between tuna muscle cells were observed directly, the deformation degree of muscle tissue pores during crystallization was evaluated, and the effect of freeze-thaw times on tuna samples was analyzed. The effects of the use of cryoprotectant such as cellobiose and carboxylated cellulose nanofibers on ice-growth inhibition were investigated, and the reliability of the ice crystal observation results was further verified by the determination of physical properties. The results showed that carboxylated cellulose nanofibers had the best ice-growth inhibition effect, they prevented about 50% cell deformation compared with the control group, and also reduced the minimum size of ice crystal formation. In addition, the addition of cellobiose and sodium tripolyphosphate gave the ice crystals a more uniform size and roundness. The experiment proposed a stable and clear observation method for the process of intercellular ice crystal formation, and the accuracy of the observation method was further verified by some physical indicators. This may help in the selection of suitable measurement methods to directly observe ice crystal formation behavior and screen cryoprotectants. © 2024 Society of Chemical Industry.

Unveiling Competitive Adsorption in TiO2 Photocatalysis through Machine-Learning-Accelerated Molecular Dynamics, DFT, and Experimental Methods.

The efficient harnessing of solar power for water treatment via photocatalytic processes has long been constrained by the challenge of understanding and optimizing the interactions at the photocatalyst surface, particularly in the presence of nontarget cosolutes. The adsorption of these cosolutes, such as natural organic matter, onto photocatalysts can inhibit the degradation of pollutants, drastically decreasing the photocatalytic efficiency. In the present work, computational methods are employed to predict the inhibitory action of a suite of small organic molecules during TiO2 photocatalytic degradation of para-chlorobenzoic acid (pCBA). Specifically, tryptophan, coniferyl alcohol, succinic acid, gallic acid, and trimesic acid were selected as interfering agents against pCBA to observe the resulting competitive reaction kinetics via bulk and surface phase reactions according to Langmuir-Hinshelwood adsorption dynamics. Experiments revealed that trimesic and gallic acids were most competitive with pCBA, followed by succinic acid. Density functional theory (DFT) and machine learning interatomic potentials (MLIPs) were used to investigate the molecular basis of these interactions. The computational findings showed that while the type of functional group did not directly predict adsorption affinity, the spatial arrangement and electronic interactions of these groups significantly influenced adsorption dynamics and corresponding inhibitory behavior. Notably, MLIPs, derived by fine-tuning models pretrained on a vastly larger dataset, enabled the exploration of adsorption behaviors over substantially longer periods than typically possible with conventional ab initio molecular dynamics, enhancing the depth of understanding of the dynamic interaction processes. Our study thus provides a pivotal foundation for advancing photocatalytic technology in environmental applications by demonstrating the critical role of molecular-level interactions in shaping photocatalytic outcomes.

Can behaviorally inhibited preschoolers make friends?

Preschoolers who display extremely inhibited behavior are at risk for the development of anxiety disorders. However, behavioral inhibition (BI) is a multifaceted characteristic. Some children with BI are fearful when confronted by unfamiliar adults, peers, and objects; others are fearful when separated from their parents. In the present study, we examined specific features of BI that predicted observed friendship formation among preschoolers who are behaviorally inhibited. We also examined whether teacher ratings of classroom behaviors predicted friendship formation. Sixty highly inhibited children (35 female, Mage = 52.57 months) were observed during eight weekly free-play sessions with initially unfamiliar inhibited peers. Free-play periods occurred before weekly intervention sessions for children with BI and their parents. An observational protocol was developed to identify children who made a friend during the eight weekly sessions. Before the first session, different subtypes of BI were assessed by parents; preschool teachers assessed the children's classroom behaviors with familiar peers. Twenty-six children met the criteria for having made and kept a friend. Probit regression analyses revealed that parent ratings of BI among unfamiliar peers and teacher ratings of children's social anxiety before the intervention were associated with a decreased probability of making a friend. No evidence was found linking children's responses to the intervention and friendship formation. Results suggest that extremelyinhibited preschoolers are capable of making friends. Implications for future research and intervention efforts that focus on individual differences of children with BI are discussed. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

New insight into the mitigation strategy of microbiologically influenced corrosion caused by anaerobic microbial consortium based on resource conversion of obsolete antibiotics

In this work, the diversity of microbial consortium coming from a shale gas well was initially analyzed by 16 S full length sequencing, and the primary bacteria are Arciella (53.37 %), Shewanella (43.61%), and Desulfovibrio (1.95 %). These bacteria can produce large amounts of H2S using sulfate as electron acceptor. Subsequently, microbiologically influenced corrosion (MIC) behavior and MIC inhibition mechanism of norfloxacin and clindamycin hydrochloride are studied. The bacteria in anaerobic microbial consortium (AMC) significantly accelerate steel corrosion, but norfloxacin and clindamycin hydrochloride both can effectively inhibit MIC at a low concentration (40 mg/L) with inhibition efficiencies of 85.2 % and 82.7 %, respectively.

The effect of social inhibition on preschoolers' behavior problems: The moderating role of maternal parenting styles

AbstractThe present study aimed to examine the longitudinal relationship between social inhibition and behavior problems in preschoolers, as well as the potential moderating role of maternal parenting styles (authoritative, authoritarian, and permissive) in this relationship. A total of 196 preschoolers aged 3–4 years (MT1 = 3.460, SD = .594) and their mothers participated in the study, which involved two‐time points. Specifically, teachers assessed preschoolers' social inhibition at the first time point (November 2018). After 1 year (November 2019), mothers reported parenting styles and preschoolers' behavior problems. The results revealed that higher levels of social inhibition were positively associated with increased behavior problems in preschoolers. Furthermore, it was found that a high maternal authoritative parenting style buffered the positive association between social inhibition and preschoolers' behavior problems. However, maternal authoritarian and permissive parenting styles did not act as moderators. These findings emphasized the importance of maternal authoritative parenting style for behavior problems in preschoolers with social inhibition.

Comparison of Mindfulness-Based Cognitive Therapy and Integrated Transdiagnostic Psychotherapy for Emotion Regulation and Distress Tolerance

Introduction: Cardiac disease significantly impacts global health, causing substantial disability and mortality. This study compared the effectiveness of mindfulness-based cognitive therapy (MBCT) and integrated transdiagnostic psychotherapy (ITP) on emotion regulation and distress tolerance in patients with type D personality, characterized by social inhibition and negative affectivity. Methods: A semi-experimental design randomly assigned 60 cardiac patients with type D personality from Simorgh Heart Clinic, Mashhad, Iran, in 2022, to MBCT group (n = 20), ITP group (n = 20) and control group (n = 20). The MBCT and ITP groups received respective interventions, while the control group received no intervention. Emotion regulation and distress tolerance were assessed using validated scales before and after the interventions. Results: MBCT demonstrated significantly greater improvement in both emotion regulation and distress tolerance compared to ITP and the control group. Conclusion: This study suggests that MBCT may be a more effective intervention than ITP in improving emotion regulation and distress tolerance in cardiac patients with type D personality. Mindfulness-based approaches could offer valuable tools for managing emotional challenges in this population.

Psychometric Properties of the Chinese Version of the Core Symptom Index: A Study among Chinese Parents of Children with Autistic Spectrum Disorders.

(1) Background: Parents of children with autism spectrum disorders often experience psychological distress, which can affect the quality of childcare they provide. It is crucial to screen for psychiatric symptoms among these parents. The core symptom index (CSI) is a widely recognized tool used to assess general symptoms, including depression, anxiety, and somatic issues. It has proven validity and reliability across diverse Thai populations. Given the cultural similarities between Thai and Chinese populations, the CSI has been successfully implemented within the Chinese population. Nevertheless, it is crucial to research its validity and reliability in the general Chinese population. This study aimed to investigate the psychometric properties of the Chinese version of the CSI among parents of children with autism spectrum disorders using confirmatory factor analysis (CFA). (2) Methods: A total of 794 Chinese parents raising children with autism participated in this study. All completed the CSI, along with the social inhibition subscale of the Interpersonal Problems Inventory and the Couple Satisfaction Index. Factorial validity was assessed using CFA to determine how well the bifactor three-factor model fits the data. Various structural models were compared using model fit indices. Convergent and discriminant validity were examined by exploring correlations with the social inhibition subscale and the Couple Satisfaction Index. Invariance testing of the CSI was conducted across multiple groups based on gender, age, and education using CFA. The reliability of the CSI was evaluated using McDonald's omega coefficients. (3) Results: The bifactor model emerged as the best-fitting model for the data, suggesting that the total score of the CSI adequately represents overall psychiatric symptoms. The CSI exhibited significant correlations with the social inhibition subscale (r = 0.41, p < 0.01) and smaller correlation coefficients with the Couple Satisfaction Index (r = -0.16, p < 0.05), indicating both convergent and discriminant validity. The invariant test results support scalar invariance levels based on gender and age but only partial invariance for education. The Chinese version of the CSI demonstrated high consistency, with McDonald's omega coefficients ranging between 0.86 and 0.95. (4) Conclusions: The bifactor model of the Chinese version of the CSI is validated, making it a suitable tool for measuring depression, anxiety, and somatization symptoms among parent(s) of children with autism spectrum disorders. Further research on other Chinese populations is encouraged.

Corrosion inhibition performance of RNC-n on aluminum alloy surface in alkaline solution

The corrosion inhibition behavior of glycine surfactants with different carbon chain lengths (RNC-n, n = 8, 12, 14) of AA2024-T3 aluminum alloy in 0.01 mol·L−1 NaOH solution was investigated. The weight loss and electrochemical methods, XPS, SEM/EDS techniques, quantum chemical calculations, and molecular dynamics simulations were used for studying the corrosion inhibition properties, adsorption behavior, and corrosion inhibition mechanism. When the maximum solubility of 0.01 mol·L−1 was achieved, the inhibition effectiveness of RNC-8 reached 90.55 %. Both RNC-12 and RNC-14 exhibited inhibitory efficiencies of 92.81 % at 0.005 mol·L−1 and 91.83 % at 0.0005 mol·L−1. RNC-n was shown to be an anodic corrosion inhibitor, since its impact on the anodic reaction was larger than on the cathodic one. RNC-n was able to successfully adsorb on the aluminum surface and form a protective film, which hindered further corrosion damage of the aluminum by the alkaline solution. In addition, the adsorption sites of RNC-n molecules were analyzed, and it was found that the adsorption sites of the corrosion inhibitor were mainly in the carboxyl group. Therefore, this paper can provide some theoretical support for the protection of aluminum alloys against corrosion in alkaline medium.