Behavioral Changes Research Articles

Complementation testing identifies genes mediating effects at quantitative trait loci underlying fear-related behavior

Knowing the genes involved in quantitative traits provides an entry point to understanding the biological bases of behavior, but there are very few examples where the pathway from genetic locus to behavioral change is known. To explore the role of specific genes in fear behavior, we mapped three fear-related traits, tested fourteen genes at six quantitative trait loci (QTLs) by quantitative complementation, and identified six genes. Four genes, Lamp, Ptprd, Nptx2, and Sh3gl, have known roles in synapse function; the fifth, Psip1, was not previously implicated in behavior; and the sixth is a long non-coding RNA, 4933413L06Rik, of unknown function. Variation in transcriptome and epigenetic modalities occurred preferentially in excitatory neurons, suggesting that genetic variation is more permissible in excitatory than inhibitory neuronal circuits. Our results relieve a bottleneck in using genetic mapping of QTLs to uncover biology underlying behavior and prompt a reconsideration of expected relationships between genetic and functional variation.

Relationships, stability, and authenticity: How being yourself is ‘the’ key to community sport coaching and youth work

AbstractThe fields of youth work and community sport development both use participation in sport as a means by which to engage young people and support behavioural change. This is achieved through social intervention programmes (whether part of broader or specific approaches, or individual, group, or community contexts), that specifically address community and psychological wellbeing. While extensive bodies of literature support effective practices in both fields, there are fewer related to the intersubjectivity between them. Given, in the UK context at least, the crossover of funded programmes, objectives, and practice in an applied and policy sense, this study sought to investigate what practitioners in both fields considered best practice relative to how they facilitated appreciable changes in pro‐social behaviour and lifestyle trajectories. This study used semi‐structured interviews with nine participants who all had experience of working in both community sport coaching and youth work. The findings suggest that youth workers and community sport coaches can fashion effective practice through working climates that actively ensure stability and connections, and that authentic projection of self, one that means practitioners must care and have the interest of the young people at heart, are essential to create positive psychological change through meaningful relationships. Please refer to the Supplementary Material section to find this article's Community and Social Impact Statement.

Allied Health Professional Knowledge And Clinical Practice In Telehealth Exercise Behavioural Change For Multiple Sclerosis

Allied Health Professional Knowledge And Clinical Practice In Telehealth Exercise Behavioural Change For Multiple Sclerosis

Storytelling as a Tool for Activist Public Relations: A Qualitative Study in Case of Women

This study focuses on storytelling in activist public relations. Stories emerge as an important "activist public relations" tool in non-governmental organizations' social change and awareness-raising efforts. The research aims to investigate both short and long-term effects of storytelling on emotions, awareness levels, and behavioral changes across different age groups. To illustrate the use of storytelling in activist public relations within the cosmetics industry, the researchers selected the short film "Save Ralph," produced by Humane Society International in 2021. The short film tells in an emotional tone, from the mouth of a rabbit, what happened to him during cosmetic experiments. The research, employing a qualitative research design, comprises three stages. Firstly, a survey was conducted among 30 women from various age groups to gather insights into their definitions of cosmetic products, usage frequency, and factors influencing their preferences. In the second stage, participants were shown the selected short film, followed by in-depth interviews. Lastly, follow-up interviews were conducted with the same group of women three months later. The findings revealed that storytelling had the most significant impact on emotions, awareness levels, and behavioral changes among women aged 18-23. This underscores the effectiveness of storytelling as a strategy for driving social change and raising awareness within activist public relations initiatives.

Visioning sustainable futures: Exposure to positive visions increases individual and collective intention to act for a decarbonated world

A key factor for behavioural change, when individuals are already concerned by environmental crises, is individuals’ perception of how they could cope with such an issue in an effective way, as well as their perception of their ability to imagine environmental cognitive alternatives to the behavioural status quo. Is it possible to boost these perceptions through the presentation of positive visions of the future? In this experimental study (N = 300), we tested whether being exposed to positive visions of a decarbonated future influences individuals’ perceived ability to imagine environmental cognitive alternatives as well as their efficacy beliefs, and their intention to engage in climate change mitigation behaviour at an individual and collective level. More precisely, we compared the effects of being exposed to a positive vision focused on either eco-sufficiency or eco-efficiency through green technologies, to achieve the decarbonated world described (including also a control condition). Results confirmed that, regardless of the focus of the positive vision, being exposed to a positive vision is sufficient to increase individuals’ perceived ability to imagine the future, their perceived collective efficacy, and their intention to engage in individual pro-environmental consumption behaviours, technology-use behaviours, and collective behaviours. These findings explore and explain the psychological effects of mere exposure to positive visions on socio-cognitive determinants of behavioural change, which could become an effective strategy to motivate pro-environmental behavioural change in communication and education campaigns.

Gastrointestinal and Hepatic Manifestations of COVID-19 in Children: A Systematic Review and Meta-analysis

Background. Children with COVID-19 may present with gastrointestinal (GI) symptoms and liver dysfunction.Objective. To determine the type and prevalence of gastrointestinal (GI) and hepatic manifestations of COVID-19 in children and its association with severity of illness. Methods. A systematic literature search was done from inception until January 4, 2021 using PubMed, CochraneLibrary, Google Scholar and prepublication repositories with no language restrictions. Studies that reported thedemographic and clinical features of children with COVID-19 and provided data on their GI and hepatic signs and symptoms were included. Prevalence of GI and hepatic manifestations were pooled using Stata14. Results. We included 58 studies with total of 4497 participants. Overall, one-third of children with COVID-19presented with at least one GI symptom (33.8%; 95% confidence interval (CI) 23.0, 45.4; I2 97.5%; 42 studies, 3327 participants) with abdominal pain, nausea or vomiting, and diarrhea each occurring in approximately 20%. Children with severe COVID-19 were more likely to present with GI symptoms (odds ratio 2.59; 95% CI 1.35, 4.99; I2 24%; 4 studies, 773 participants). The pooled prevalence of elevated transaminases was 11% for both AST (11.3%, 95% CI 4.9, 19.3; I2 74.7%; 11 studies, 447 participants) and ALT (11.2%, 95% CI 7.1, 16.0; I2 40.8%; 15 studies, 513 participants). Hepatic findings such as jaundice (2-17%), hepatomegaly (2%) or behavioral changes (2%) from hepatic encephalopathy were variably reported by a few studies. The degree of heterogeneity was not improved on exclusion of studies with poor quality, but markedly improved on subgroup analysis according to geographical region and presence of MIS-C. Studies from China showed that children with COVID-19 had significantly lower pooled prevalence for any of the GI symptoms with low degree of heterogeneity, particularly for diarrhea, nausea/vomiting, and abdominal pain, all of which had I2 of 0%. Those with multisystem inflammatory syndrome in children (MIS-C) had significantly more common GI symptoms and increased transaminases than those without. Conclusion. One-third of children with COVID-19 exhibit at least one GI symptom and more likely presentin those with severe disease. Elevated transaminases were present in 10%. Prevalence of GI and hepaticmanifestations were higher among children with MIS-C.

The Effect of Problem Based Learning Model on Mathematics Learning Outcomes of Class VIII Students at SMP Negeri 10 Bengkulu City

Learning outcomes was the accomplishments of educational purpose for students who take part in the teaching and process of learning, student outcomes of learning are fundamentally behavioral changes brought about by learning. According to the findings, it was discovered that the outcomes of learning in mathematics of Class VIII students of SMPN 10 Kota Bengkulu for the 2022/2023 academic year were still low. So that the effort that can be made to increase student outcomes of learning in mathematics is to apply problem based learning learning models. This research purpose to see whether the the outcomes of learning in mathematics of students who study using the problem-based learning model in class VIII SMP Negeri 10 Kota Bengkulu was more good than the outcomes of learning by students using learning in conventional models.This research type was a quasi-experimental design with a non-equivalent posttest only control group design. The selection for sample was conducted using technique by simple random sampling, so that class VIIID was selected as the class for experimental and class VIIC as the class for control. The instruments in research were in consist of quizzes and final tests outcomes of learning in the form of essays. According on the research data analysis results at the real level α = 0.05 using the t test obtained P-value = 0.018, that means that P-value < ???? so reject H0. This shows that the outcomes of learning by students in mathematics who study using the model of problem-based learning are more good than students who study using learning in models of conventional in class VIII SMPN 10 Kota Bengkulu.

Clinical heterogeneity within the ALS-FTD spectrum in a family with a homozygous optineurin mutation.

Mutations in the gene encoding for optineurin (OPTN) have been reported in the context of different neurodegenerative diseases including the amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) spectrum. Based on single case reports, neuropathological data in OPTN mutation carriers have revealed transactive response DNA-binding protein 43 kDa (TDP-43) pathology, in addition to accumulations of tau and alpha-synuclein. Herein, we present two siblings from a consanguineous family with a homozygous frameshift mutation in the OPTN gene and different clinical presentations. Both affected siblings underwent (i) clinical, (ii) neurophysiological, (iii) neuropsychological, (iv) radiological, and (v) laboratory examinations, and (vi) whole-exome sequencing (WES). Postmortem histopathological examination was conducted in the index patient, who deceased at the age of 41. The index patient developed rapidly progressing clinical features of upper and lower motor neuron dysfunction as well as apathy and cognitive deterioration at the age of 41. Autopsy revealed an ALS-FTLD pattern associated with prominent neuronal and oligodendroglial TDP-43 pathology, and an atypical limbic 4-repeat tau pathology reminiscent of argyrophilic grain disease. The brother of the index patient exhibited behavioral changes and mnestic deficits at the age of 38 and was diagnosed with behavioral FTD 5 years later, without any evidence of motor neuron dysfunction. WES revealed a homozygous frameshift mutation in the OPTN gene in both siblings (NM_001008212.2: c.1078_1079del; p.Lys360ValfsTer18). OPTN mutations can be associated with extensive TDP-43 pathology and limbic-predominant tauopathy and present with a heterogeneous clinical phenotype within the ALS-FTD spectrum within the same family.

Knowledge, Attitude, and Behavior of Farmers Towards Restoration of Degraded Land; the Cases of Harbo and Adea districts in the Oromia Region, Ethiopia

Land restoration is one of Ethiopia's top priorities for aligning development efforts with a climate-resilient green economy. In Ethiopia, initiatives to rehabilitate degraded land are generally evaluated in terms of the local people's economic and environmental impacts. Farmers' knowledge, attitudes, and actions toward land restoration, on the other hand, have to be taken into consideration for long-term natural resource conservation. As a consequence, this study examines the relationships between farmers' knowledge, attitude, and contributions to behavioral change in the restoration of degraded land. Data were collected from 120 farmers who participated in the restoration of degraded land. Structural equation models and mediation analyses were utilized for path analysis. The findings indicated that farmers had a good understanding of land restoration techniques. Analysis of the causal models revealed that farmers' attitude toward land restoration is highly influenced by their knowledge level of farmers. The outcome also revealed that positive attitudes of farmers resulted in behavioral change towards land restoration. Effective local community participation in the land restoration process and strengthening of their knowledge and attitudes that influence their behavior should be the cornerstones of sustainable land restoration.

Co-design and mixed methods evaluation of an interdisciplinary digital resource for undergraduate health profession students to improve the prevention, recognition, and management of delirium in Ireland: a study protocol.

Delirium is a common symptom of acute illness which is potentially avoidable with early recognition and intervention. Despite being a growing concern globally, delirium remains underdiagnosed and poorly reported, with limited understanding of effective delirium education for undergraduate health profession students. Digital resources could be an effective approach to improving professional knowledge of delirium, but studies utilising these with more than one profession are limited, and no evidence-based, interdisciplinary, digital delirium education resources are reported. This study aims to co-design and evaluate a digital resource for undergraduate health profession students across the island of Ireland to improve their ability to prevent, recognise, and manage delirium alongside interdisciplinary colleagues. Utilising a logic model, three workstreams have been identified. Workstream 1 will comprise three phases: (1) a systematic review identifying the format, methods, and content of existing digital delirium education interventions for health profession students, and their effect on knowledge, self-efficacy, and behavioural change; (2) focus groups with health profession students to determine awareness and experiences of delirium care; and (3) a Delphi survey informed by findings from the systematic review, focus groups, and input from the research team and expert reference group to identify resource priorities. Workstream 2 will involve the co-design of the digital resource through workshops (n = 4) with key stakeholders, including health profession students, professionals, and individuals with lived experience of delirium. Lastly, Workstream 3 will involve a mixed methods evaluation of the digital resource. Outcomes include changes to delirium knowledge and self-efficacy towards delirium care, and health profession students experience of using the resource. Given the dearth of interdisciplinary educational resources on delirium for health profession students, a co-designed, interprofessional, digital education resource will be well-positioned to shape undergraduate delirium education. This research may enhance delirium education and the self-efficacy of future health professionals in providing delirium care, thereby improving practice and patients' experiences and outcomes. Not applicable.

Liaoning University ChopMelon Net Project: Innovative Research on Sustainable Education Based on Real Social Issues

The purpose of this study is to evaluate how the ChopMelon Net online learning platform can contribute to the effectiveness of sustainable education by incorporating real social issues. The core innovation of ChopMelon Net is that it provides a learning environment that connects learners directly to real-world challenges and aims to enhance learners’ understanding of sustainable development theory. The study employed the technology acceptance model (TAM), theory of planned behavior (TPB), and knowledge–Behavior gap theory (KBGT) to design the questionnaires and semi-structured interviews in order to comprehensively assess the impact of ChopMelon Net on learners’ skill enhancement. The results showed that learners not only showed significant improvement in critical thinking and problem-solving skills after using ChopMelon Net, but also expressed a high level of satisfaction with the educational content and interactive experience provided by the platform. In addition, the study found that ChopMelon Net effectively promoted learners’ awareness of the importance of sustainable education and behavioral change through its innovative educational model, which provides important empirical support for future sustainable education practices and the design of online education platforms. This study highlights the importance and effectiveness of incorporating real social issues into the teaching and learning process, with far-reaching implications for sustainable innovation in education.

The role of manipulative trophically transmitted parasites in the stability of a predator–prey community

In this paper, we are interested in the effect of a trophically transmitted parasite on the structure and dynamics of a resident predator–prey community. The parasite, apart from increasing the mortality rates of its hosts, can also change their physiology or their behaviour, which is known as trait-mediated indirect interaction. We assume that parasite transmission, which entails rapid physiological or behavioural change, is a fast process with respect to the community dynamics, including prey and predator growths and predation. This existence of different time scales allows us to provide analytical results to understand some conditions under which the parasite change the dynamics of the predator–prey community. Thus, we are able to find conditions under which indirect trait-mediated interactions induced by the parasite lead to a coexistence between predators and prey that would not occur in its absence. We also provide conditions, evolutionary deleterious, that ensure the extinction of a predator–prey community that would be viable without parasite intervention. Finally, we show situations in which the action of the parasite destabilizes the predator–prey system without eliminating it, producing oscillations, the mechanism of which is analysed.

Differential effects of high-fat diet on endocrine, metabolic and depressive-like behaviors in male and female rats

The complications of obesity extend beyond the periphery to the central nervous system (CNS) and include an increased risk of developing neuropsychiatric co-morbidities like depressive illness. Preclinical studies support this concept, including studies that have examined the effects of a high-fat diet (HFD) on depressive-like behaviors. Although women are approximately two-fold more likely to develop depressive illness compared to men, most preclinical studies have focused on the effects of HFD in male rodents. Accordingly, the goal of this study was to examine depressive-like behaviors in male and female rats provided access to a HFD. In agreement with prior studies, male and female rats provided a HFD segregate into an obesity phenotype (i.e., diet-induced obesity; DIO) or a diet resistant (DR) phenotype. Upon confirmation of the DR and DIO phenotypes, behavioral assays were performed in control chow, DR, and DIO rats. In the sucrose preference test, male DIO rats exhibited significant decreases in sucrose consumption (i.e., anhedonia) compared to male DR and male control rats. In the forced swim test (FST), male DIO rats exhibited increases in immobility and decreases in climbing behaviors in the pre-test sessions. Interestingly, male DR rats exhibited these same changes in both the pre-test and test sessions of the FST, suggesting that consumption of a HFD, even in the absence of the development of an obesity phenotype, has behavioral consequences. Female rats did not exhibit differences in sucrose preference, but female DIO rats exhibited increases in immobility exclusively in the test session of the FST, behavioral changes that were not affected by the stage of the estrous cycle. Collectively, these studies demonstrate that access to a HFD elicits different behavioral outcomes in male and female rats.

Gamificação na prevenção de queimaduras: desenvolvimento de um jogo infantil

Burns are a public health problem and result in physical, psychological as well as social repercussions, leading to death. The objective of this study is to develop a game that can distribute information, with the focus on burn prevention and serving as an alternative for health education. This is technological research for the experimental development of a game focusing on the prevention of childhood burns and using the problematization method based on the Maguerez Arch. Gamification is an innovative alternative for training and for behavioral changing and health education is a strategic tool that helps and strengthens care. The game was made for children aged six to ten years old and will be made available in a virtual environment for Android devices. Assistance from a programming language professional was required to program the game. Nowadays, it is necessary to keep up with innovations and technologies, improving interaction with children.

The continuance intention to vaccinate against COVID-19: An empirical study from Malaysia.

Vaccination has been one of the most effective preventive strategies to contain the COVID-19 pandemic. However, as the COVID-19 vaccines' effect wanes off after some time and given their reduced level of protection against mutation strains of the virus, the calls for boosters and second boosters signal the need for continuous vaccination for the foreseeable future. As Malaysia transitions into the endemic phase, the nation's ability to co-exist with the virus in the endemic phase will hinge on people's continuance intention to be vaccinated against the virus. Adapting the expectations confirmation model (ECM) to the public health context and in a developing country, this study integrates the ECM with the health belief model (HBM) and the theory of reasoned action (TRA) to examine the inter-relationships of the predictors of people's continuance intention to vaccinate against COVID-19. Data were collected using self-administered questionnaires from 1,914 respondents aged 18 and above by a marketing consulting firm via its online panel. The partial least squares structural equation modeling (PLS-SEM) technique was used to analyze the data. Out of the 1,914 respondents, 55.9% reported having a continuance intention to vaccinate against COVID-19, similar to other developing countries. The multivariate analysis revealed that perceived usefulness and satisfaction significantly influenced individuals' continuance intention to vaccinate against COVID-19. Additionally, attitude was found to play a key role in influencing behavioral change among individuals towards their perceptions of continuously getting vaccinated against COVID-19. By integrating three theoretical frameworks (i.e., HBM, TRA and ECM), this study showed that behavioral characteristics could provide insights towards continuance vaccination intention. Hence, policymakers and key stakeholders can develop effective public health strategies or interventions to encourage vaccine booster uptake by targeting behavioral factors such as perceived usefulness, attitude, satisfaction, and subjective norms.

"Service design for behavioral change in impulse buying via mobile shopping applications during early adulthood - based on FBM model and design strategies for persuasive behavioral design"

"Service design for behavioral change in impulse buying via mobile shopping applications during early adulthood - based on FBM model and design strategies for persuasive behavioral design"

Bayesian workflow for time-varying transmission in stratified compartmental infectious disease transmission models.

Compartmental models that describe infectious disease transmission across subpopulations are central for assessing the impact of non-pharmaceutical interventions, behavioral changes and seasonal effects on the spread of respiratory infections. We present a Bayesian workflow for such models, including four features: (1) an adjustment for incomplete case ascertainment, (2) an adequate sampling distribution of laboratory-confirmed cases, (3) a flexible, time-varying transmission rate, and (4) a stratification by age group. Within the workflow, we benchmarked the performance of various implementations of two of these features (2 and 3). For the second feature, we used SARS-CoV-2 data from the canton of Geneva (Switzerland) and found that a quasi-Poisson distribution is the most suitable sampling distribution for describing the overdispersion in the observed laboratory-confirmed cases. For the third feature, we implemented three methods: Brownian motion, B-splines, and approximate Gaussian processes (aGP). We compared their performance in terms of the number of effective samples per second, and the error and sharpness in estimating the time-varying transmission rate over a selection of ordinary differential equation solvers and tuning parameters, using simulated seroprevalence and laboratory-confirmed case data. Even though all methods could recover the time-varying dynamics in the transmission rate accurately, we found that B-splines perform up to four and ten times faster than Brownian motion and aGPs, respectively. We validated the B-spline model with simulated age-stratified data. We applied this model to 2020 laboratory-confirmed SARS-CoV-2 cases and two seroprevalence studies from the canton of Geneva. This resulted in detailed estimates of the transmission rate over time and the case ascertainment. Our results illustrate the potential of the presented workflow including stratified transmission to estimate age-specific epidemiological parameters. The workflow is freely available in the R package HETTMO, and can be easily adapted and applied to other infectious diseases.

Histopathological alterations in the vital organs of Indian major carp Labeo rohita exposed to monosodium glutamate (MSG)

BackgroundMonosodium glutamate (MSG E621) is one of the most popular flavouring agents of modern times and is widely used in many commercially packed food and even in house hold cooking. Previous studies revealed that excessive intake of MSG in diet causes obesity, metabolic defects, nephrotoxicity, neurotoxicity and hepatotoxicity in rats, but no reports are available in the literature about the ecotoxicological assessment of MSG by using fishes as a bioindicators. Since fishes are important consumer in aquatic food chain and directly linked with human health status, the present study was aimed to investigate the impact of MSG in freshwater fish Labeo rohita by using histological biomarkers.ResultsNinety-six h-LC50 of MSG to Labeo rohita was determined (1.5 g/L), and fish exposed to sub-lethal concentration of MSG (1/10th of 96 h-LC50 concentration of MSG (150 mg/L)) showed distinguished behavioural changes like erratic movement, loss of appetite and excessive mucous secretion all over the body as an adaptive syndrome to avoid the direct exposure to MSG in the medium. Histopathological analysis clearly depicts severe damages in the vital organs of fish. In gills, epithelial necrosis, hypertrophy, hyperplasia, primary and secondary gill lamellae degeneration, oedema, fusion of adjacent secondary lamellae and rupture of gill epithelium were observed. The intensity of tissue damage was increased as the exposure period was extended. The liver displayed vein congestion, vacuole formation, degeneration in parenchymal cells and bile stagnation, whereas MSG-treated kidney tissue showed high interstitial inflammation. Among the vital organs gill and liver displayed the highest histopathological alterations.ConclusionsThe present study clearly demonstrated that MSG is toxic to fish and able to cause significant damages in the vital organs as the exposure period was extended. Since the studies on the toxicity of MSG to fish are rare, the present investigation may contribute to the scarce literature on sub-lethal toxicity of MSG to freshwater fishes.

The Impact of Training and Development on Job Performance: A Comprehensive Analysis

This study examines the profound impact of training and development initiatives on employee job performance within organizational settings. By synthesizing existing literature and empirical evidence, the research explores the multifaceted dynamics influencing how training and development programs enhance employee skills, knowledge, and performance outcomes. Key aspects investigated include the design and implementation of training programs, the role of employee engagement and motivation, and the alignment of training objectives with organizational goals. Furthermore, the study assesses the efficacy of various training methods in fostering skill acquisition, knowledge transfer, and behavioral change among employees. Additionally, the research delves into organizational factors such as culture, leadership support, and learning climate, elucidating their influence on the success of training and development initiatives. It examines feedback mechanisms, coaching, and mentoring as pivotal components reinforcing learning and driving continuous improvement in job performance. Furthermore, the study explores the repercussions of training and development on employee engagement, job satisfaction, and retention, highlighting the significance of investing in employee development to cultivate a skilled, motivated workforce and bolster organizational performance. This comprehensive analysis contributes nuanced insights into the strategic importance of training and development, offering actionable recommendations for organizations aiming to optimize employee performance, foster a culture of learning, and attain sustained success in today's competitive landscape.

Effect of Bullying on Learners with Autism Spectrum Disorder: A Case of a Selected Special Unit at the Mainstream in Kabwe Zambia

This manuscript was a study which focused on the effects of bullying learners with Autism Spectrum Disorder in mainstream. The main objectives of the study were to assess the reasons of bullying learners with autism Spectrum Disorder, to establish how bulling affected learners with autism and to find out interventions the school had to put in place to stop bullying of learners with Autism Spectrum Disorder. The study was conducted at the special unit at the mainstream and homes for learners with autism because that is where these learners were found. The study was qualitative in nature. Thus the instruments for data collection were the focused group discussion for parents, special education teachers, regular teachers and school administrators, structured interview guide for regular and Guidance teacher and lastly observation checklist for parents. The study revealed that the reasons for bulling learners with autism were as a result of failing to socialize with peers, being violent towards friends and having an antisocial behavior, failing to speak properly when with friends and not looking at the person they were talking to. The study also established the negative effects bulling had on these leaners such as increased violence, changing of antisocial behavior from bad to worse, they became more depressed and their low self-esteem became worse too. With regards interventions that were put in place by the school to stop bullying of learners with autism, the school plan helped learners develop and regain their loss of confidence by involving them in school activities such as academic work and giving them simpler work and reward them through praise or giving them something for doing something commendable, by helping them improve on their social interactions through encouraging them to interact more frequently with peers in order to correct their lost confidence. Suggested recommendations from the study includes, putting up a deliberate policy by the school to help autistic learners develop commutative skills, socialize frequently and positively with peers at least every day. Introduction of anti-bullying club at school to make other learners respect and accept these children’s condition without segregation. It was also recommended that the future study on the effects of bulling learners with autism in the mainstream would be necessary to establish more challenges faced by these learners in the mainstream and the research concerning autistic learners should be included in all mainstream schools in central province of Zambia in order to help these learners fully.