A large-scale field testing program for the study of residual forces in pre-stressed high-strength concrete (PHC) pipe piles is presented in this paper. Five open-ended PHC pipe piles with 13 or 18 m in embedded length were installed and used for static loading tests at a building site in Hangzhou, China. All the piles were instrumented with fiber Bragg grating (FBG) strain gauges. The residual forces in these piles were recorded during and after installation. The measured load transfer data along a pile during the static loading tests are reported. The effect of the residual force on the interpretation of the load transfer behavior is discussed. The field data show that residual force along the installed pile increases approximately exponentially to the neutral plane and then reduces towards the toe. The residual force decreases with time to a stable value after pile jacking due to the secondary interaction between the pile and the disturbed soil around the pile and other factors. The large residual forces along the PHC pipe piles significantly affect the evaluation of the pile load distributions, and thus the shaft and toe resistances. The conventional bearing capacity theory tends to overestimate the shaft resistance at positions above the neutral plane and underestimate the shaft resistance at positions below the neutral plane, and the toe resistance for an open-ended PHC pipe piles founded in stratified soils.