The experiment was studied to evaluate the fourteen different fungicides against M. oryzae pv. triticum in laboratory and pot experiment from August 2016 to October 2017. The result of the in-vitro evaluation showed that a 100% reduction of radial mycelial growth was obtained in Amiscore 32.5 SC, Bavistin DF, Cabrio Top, Xtracare 300 EC, Nativo 75 WG, Provax 200 WP and Trooper 75 WP. Nativo 75 WG (0.2%) revealed the highest (85.38%) reduction of disease incidence over control while Provax 200 WP (0.3%) showed an efficacy of 82.14% in reducing disease incidence in the pot experiment. The lowest (3.70%) disease severity was found in Nativo 75 WG, and Provax 200 WP also exhibited 4.40% disease severity. A maximum number of healthy grain/ear (16.40) was observed in Nativo 75 WG, and Provax 200 WP was demonstrated with healthy grain (15.00), which was close to Nativo 75 WG. In grain weight/ear, Nativo 75 WG (0.2%) led to an impressive increase of 160.47% over control.