Let $G \simeq M \rtimes C$ be an $n$-generator group which is a split extension of an Abelian group $M$ by a cyclic group $C$. We study the Nielsen equivalence classes and T-systems of generating $n$-tuples of $G$. The subgroup $M$ can be turned into a finitely generated faithful module over a suitable quotient $R$ of the integral group ring of $C$. When $C$ is infinite, we show that the Nielsen equivalence classes of the generating $n$-tuples of $G$ correspond bijectively to the orbits of unimodular rows in $M^{n -1}$ under the action of a subgroup of GL$\_{n - 1}(R)$. Making no assumption on the cardinality of $C$, we exhibit a complete invariant of Nielsen equivalence in the case $M \simeq R$. As an application, we classify Nielsen equivalence classes and T-systems of soluble Baumslag–Solitar groups, split metacyclic groups and lamplighter groups.