The formation of isolated and fused benzo[ f ]chromene derivatives was achieved via reacting ethyl 3-amino-1-phenyl-1 H -benzo[ f ]chromene-2-carboxylate ( 1 ) with some selected reagents under basic conditions. The new compound, ethyl 3-(dimethylaminomethyleneamino)-1-phenyl-1 H -benzo[ f ]chromene-2-carboxylate ( 2 ) was prepared from compound 1 and N , N -dimethyl formamide in presence of phosphorus oxychloride under mild conditions in excellent yield using Vilsmeier reaction. Also, 10-amino-12-phenyl-9-sulfanyl-12 H -benzo[ f ] chromeno[2,3- d ]pyrimidine-11(10 H )-one ( 12 ), 10-aryl-14-phenyl-14 H -benzo[ f ]chromeno [2,3- d ][1,3,4]thiadiazolo[3,2- a ]pyrimidine-13-one ( 15 ), ethyl 3-(4-oxo-2-thioxothiazolidin-3-yl)-1-phenyl-1 H -benzo[ f ]chromene-2-carboxylate ( 18 ), ethyl 3-(4-phenyl-2-thioxothiazol-3(2 H )-yl)-1-phenyl-1 H -benzo[ f ]chromene-2-carboxylate ( 20 ), ethyl 3-acetamido-1-phenyl-1 H -benzo[ f ]chromene-2-carboxylate ( 21 ), and 10-amino-9-methyl-12-phenyl-12 H -benzo[ f ] chromeno[2,3- d ]pyrimidine-11(10 H )-one ( 23 ) were prepared . The structures of these compounds were established by elemental analysis, IR, MS and NMR spectral analysis.