Ayurveda Treatment Research Articles

Management of Herpes zoster in Ayurveda through Bloodletting therapy along with other Ayurveda treatment: A case study

Herpes zoster is a very painful disease. Generally, it is a unilateral and self-limiting condition. Inappropriate or delayed therapy might make the disease worse and increase the risk of complications such as post-herpetic neuralgia. Age-related immunosuppression and low immunity make people more susceptible to herpes infection and more likely to develop post-herpetic neuralgia (15%). According to Ayurveda, it correlates with visarpa. It is a raktapradoshaj vikara (disease caused by vitiated blood) and primarily a pitta-predominant disease manifesting twaka (skin) so visarpa is one of the major skin diseases. Here we present a case of a 66-year-old female patient with k/c/o HTN and hypothyroidism visited the OPD with symptoms of unilateral onset of blisters on the right side of the back region, the right axillary region, and the medial aspect of the right arm, within 48 hours; along with burning Pain, itching, and sleeplessness due to burning. According to Ayurveda, the patient was clinically diagnosed with pittaj visarpa. Considering pitta dosha and rakta dhatu dusti, raktmokshan was planned as the prime treatment. The patient showed improvement in burning pain after the first setting of raktamokshan. The numeric rating scale revealed that the patient experienced relief in the severity of burning pain (from 8 to 0) and itching (from 5 to 0). Other Ayurveda treatments like pittaghna chikitsa (pitta pacifying) and pradeha (local application) were used. Rapid blister formation stopped within three days of treatment, and after 28 days, all blisters crusted off and a normal skin complexion was achieved. Thus, Ayurvedic treatment was valuable and cost-effective for treating conditions like herpes. Ayurveda protects patient’s immune systems and reduces the chances of post herpetic neuralgia and reinfection.

Role of Ayurveda in the management of Post-traumatic chronic inflammatory synovitis of knee joint- A Case Report

Knee is a complex joint. It is the most commonly injured joint in the body. Trauma may injure soft tissues such as ligaments or bones of the joint. Inflammatory synovitis is one of the conditions developed after trauma. This article encompasses a diagnosed case of Post traumatic chronic inflammatory synovitis. Treatment protocol was opted considering its samprapti (Pathophysiology) as janu sandhi marmaghata. Treatment was planned considering Sandhi marmaghata. Symptomatic treatment was also considered. Significant improvement was observed in parameters like range of motion, knee joint circumference, walking distance and VAS scale within a week. No recurrence observed even after 1 year of suspended treatment. This multimodular Ayurveda treatment appears to be safe and efficient for early recovery and better outcomes.

Management of chemotherapy adversity through Ayurveda: An experience

Abstract Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020. Chemotherapy is the largely accepted treatment protocol for cancer, but it comes with an increased risk of infections and side effects. Ayurveda can be a promising adjunct therapy to minimize the adverse effects of chemoradiotherapy. A 65-year-old female who was a known case of double-vessel block suddenly developed severe abdominal pain and was treated symptomatically by a general physician. Her weight loss was consistent with multiple episodes of abdominal pain for a year after which she was diagnosed to have moderately differentiated adenocarcinoma of the cecum. The patient was managed with exploratory laparotomy (with right hemicolectomy with ileal transverse colon end-to-end anastomosis). The histopathology study reported it as a Modified Astler–Coller stage C2. Consequently, six cycles of Folfox (chemotherapy) were advised by the oncologist. Before starting the chemotherapy, Ayurveda treatment was started to combat the expected side effects of chemotherapy. The treatment protocol included Dhanyaka phanta, Suvarnamalini vasanta, Madiphala rasayana, and Guduchyadi ksheerapaka. The patient had no additional complaints during the chemotherapy and all the hematological parameters were within normal limits. The patient reported weight gain after completion of the chemotherapy. Expected side effects (hair loss, mouth sores, anorexia, diarrhea, and vomiting) were not reported during the treatment. Known side effects of chemotherapy like infection, easy bruising, bleeding, or fatigue were also not reported; therefore, the present study concludes that the side effects of chemotherapy may be controlled by Ayurveda adjunct therapy.

Role of Vasakantakadi Lehyam and Phala Ghrutam in the Management of Asthenozoospermia: A Case Study

Abstract Infertility leading to the inability to conceive is a common problem but indication of assisted reproductive technologies (ARTs) is not a mandate always. Female factors are major highlighted issues in these cases but the importance of male factors and/or some unexplained reasons are not often explored. Ayurveda is known for treatments of infertility that range in variety, and cater based on the specific needs of each case. These treatment options often are the choice of many couples who wish to conceive naturally avoiding ART. We report a case study of a couple who presented with primary infertility treated with Ayurveda treatments with primary improvements in the male component (asthenozoospermia) and addressing a secondary/subclinical infection in his female counterpart.

Adenocarcinoma of the lung treated with add-on Ayurveda treatment: A case report

Abstract Studies conducted in 2020 predicted that 1,392,179 people in India suffer from cancer. The six most common sites are breast, lung, mouth, cervix, uterus, and tongue. Among these, lung cancers are reported to have the greatest fatality rate. In the present case, a 49-year-old male patient suffering from adenocarcinoma in the upper lobe of the left lung was managed with herbo-mineral Ayurvedic combinations along with conventional treatment. He had a history of right-sided chest pain after facing a fall from stairs. The chest X-ray showed a right-sided rib fracture. However, as an additional accidental finding, a 3-cm mass on the upper lobe of the left lung was also visible, which was found malignant after the detailed investigations. The patient was initially treated with conventional treatment and surgery, followed by chemotherapy. During chemotherapy, he had complaints of pain, numbness of hands and legs, nausea, anorexia, and severe weakness. Hence, concurrent Ayurvedic treatment was also started after the second cycle of chemotherapy (January 27, 2019), and after completing the modern treatment, Ayurveda treatment was continued till May 27, 2023, accounting for five years approximately. The combination therapy module provided complete symptom alleviation and marked improvement in the positron emission tomography scan that showed marked improvement and did not show any new abnormality in subsequent follow-ups. No recurrences were noticed for the last more than four years. The fact that all of the symptoms have alleviated and investigations show no abnormality is suggestive that the add-on Ayurveda treatment in this case of adenocarcinoma has aided the patient with a more than four year disease-free survival along with the good quality of life as determined by Karnofsky score (90/100).

Efficacy and safety of Ayurveda interventions for nonalcoholic fatty liver disease: A protocol for systematic review

Abstract This systematic review aimed is to find evidence about the efficacy and safety of Ayurvedic management for nonalcoholic fatty liver disease (NAFLD). This systematic review protocol was developed following the Preferred Reporting Items for Systematic Review and Meta-Analysis protocol statement. For this systematic review, articles will be selected from electronic databases such as Pubmed, AYUSH Research portal, Digital Helpline for Ayurvedic Research Articles, Ayurvedic Research Database, Cochrane Central Register of Controlled Trials, Google Scholar, Clinical trial registries, and clinical studies published in relevant journals. There will be no restriction on the study type or publication date. Two review authors will independently extract data from the selected studies on the study characteristics (publication-related information, methodology, participants, interventions, comparators, outcomes, and results) in a prestructured format for data analysis and assessment of study quality. The risk of bias in the selected studies will be assessed through suitable existing tools. The meta-analysis will also be conducted, if feasible. If meta-analysis is not possible, the results will be summarized as a systematic qualitative synthesis. This systematic review will summarize the available evidence about the safety and efficacy of Ayurveda interventions in treating NAFLD. It will also provide ideas for future research to generate good-quality evidence regarding the efficacy and safety of Ayurvedic interventions in NAFLD. Study registration: Registered with PROSPERO, Reg. No. CRD42022321063.

A prospective, open-label, randomized, active control, parallel-group trial on the efficacy of Darvyadi Leha in iron deficiency anemia of children: Study protocol of a randomized controlled trial

Abstract BACKGROUND: Iron deficiency anemia (IDA) is a major health problem among children in India. Due to the adverse effects of oral iron supplementation, there is a need to find an alternative therapeutic option for IDA, which is safe, tolerable, with comparable efficacy. OBJECTIVE: This clinical study is designed to determine the efficacy and safety of Darvyadi Leha in IDA of children compared with ferrous ascorbate. MATERIALS AND METHODS: This prospective, open-label, randomized, active control, parallel-group trial will be conducted at Uttarakhand Ayurved University, Gurukul Campus, Haridwar. A total of 76 participants will be enrolled in the study. Patients of any gender aged 3–12 years with IDA, having hemoglobin 7.5–11 g/dL and serum ferritin less than 15 mcg/dL will be considered for enrollment in the study. The enrolled participants will be given a tablet of Albendazole 400-mg single dose for deworming. Thereafter, they will be randomly divided into two groups. Patients of Group A will be administered Darvyadi Leha 4, 7, 9, and 12 g/day in two equally divided doses for age groups 3–5, 5–8, 8–10, and 10–12 years, respectively, for 90 days. Patients of group B will be administered ferrous ascorbate 4 mg/kg/day twice daily for 90 days. The outcome measures are changes in hemoglobin level, ferritin level, red blood cell count, mean corpuscular volume, mean corpuscular hemoglobin, and reticulocyte count. Patients will also be assessed for graded subjective parameters on each visit. Safety will be assessed based on the incidence of adverse events, and changes in liver and kidney function tests. DISCUSSION: Ayurveda formulations have been used for the management of anemia in routine clinical practice for adults. Further, several research studies have also been conducted regarding the same. However, the use of Ayurveda interventions in anemia of children is less common, and a few randomized controlled studies on anemia of children have been conducted. So, it is expected that the outcomes of this trial will suggest probable therapeutic options for the effective management of IDA of children. TRIAL REGISTRATION: CTRI/2022/07/044074

Leads towards non-invasive Ayurveda interventions in Stana vidradhi (~lactational breast abscess) management – An experience

Abstract A lactational breast abscess is the most common complication met in breastfeeding women, which serves as the common cause of discontinuation of breastfeeding. The conventional treatment choice for breast abscess is incisive drainage that is reportedly associated with few limitations. Ayurveda offers a multidimensional approach in the treatment of Vidradhi, which resembles abscess on clinical correlation. A case of a 25 year old multiparous woman, eight months postpartum with Stana vidradhi (~lactational breast abscess) in Pachyamanavastha (~transforming stage of disease) presented to the outpatient department. She was treated with Apatarpana (~depleting therapy), internal Ayurveda medicines, and in-situ non-invasive procedures for seven days. This intervention protocol resulted in a marked resolution of complaints along with a completely healed wound without a scar on the follow-up visit after one week. The present case offers a promising alternative for lactational breast abscess with the use of multidimensional noninvasive therapy resulting in shorter healing time and satisfactory cosmetic outcome.

Effect of Ayurveda interventions in the management of venous stasis dermatitis in a patient with type 2 diabetes: A case report

Abstract BACKGROUND: Venous insufficiency disorder associated with diabetes is a concerning condition. It can result in venous stasis dermatitis, also known as stasis eczema, characterized by inflammatory changes in the lower extremities. A similar condition is described in Ayurveda as Vatarakta, which can present as Kushtasamalakshanas (early symptoms resembling skin disorders) in the lower limbs due to vitiated Vata (bodily humor) and Rakta Dhatu (blood tissue). Ayurvedic intervention promises successful results through both Shodhana (detoxification) and Shamana (pacifying/palliative) treatment along the line of management in Vatarakta disease. Managing such problems in diabetes patients must be well-planned to prevent rising blood sugar levels. Therefore, venous stasis dermatitis in diabetic individuals can be effectively treated with Shamana (pacifying therapy) combined with Sadyovirechana (therapeutic purgation without prior administration of medicinal oil/ghee). PATIENT INFORMATION: A 54-year-old woman with type 2 diabetes mellitus approached for the Ayurvedic management of inflammatory changes on her right lower leg. She complained of hyperpigmentation, swelling, aching pain, dryness, and severe itching of the right lower leg along the medial aspect of the ankle and foot for 6 months. DIAGNOSIS: According to CEAP (clinical, etiological, anatomical, and pathophysiological) classification, this clinical condition was identified as venous stasis dermatitis with C4a Ep AP PO (changes in skin and subcutaneous tissues in the form of pigmentation/eczema, primary, perforating veins, obstruction, respectively). Before beginning Ayurvedic treatment, an assessment using the revised venous clinical severity score (RVCSS) revealed a score of 7. INTERVENTIONS: Vatashaamaka-Raktadushtihara treatment (therapy that pacifies vitiated bodily humor and purifies vitiated blood tissue) was provided to the patient for 60 days which included Deepana-Pachana (digestive and metabolism-enhancing therapy) followed by Sadyovirechana (therapeutic purgation without prior administration of medicated oil/ghee) using Nimbamritadi Eranda Tailam and Samana Treatment (pacifying therapy) including local application of Nalpamaradi Kera Tailam. OUTCOME: After 60 days of treatment, there was a noticeable improvement in all symptoms except varicosity, and the RVCSS dropped from 7 to 3. CONCLUSION: Even though treating venous insufficiency issues in diabetic individuals may be challenging, a well-planned Ayurvedic therapy regimen that includes Sadyosodhana (therapeutic purgation without prior administration of medicinal oil/ghee) and Shamanatreatment (pacifying therapy) can have excellent results and offer hope for the treatment of several disorders associated with diabetes.

Management of plaque psoriasis (~Ekakushta) through Ayurvedic approach: An experience

Abstract Psoriasis is one of a variety of illnesses brought on by the autoimmune response and is characterized by the rapid inflammatory proliferation of sick skin cells. Even though the illness was first identified several decades ago, the etiology and therapy appear to remain understudied. In Ayurveda, many herbs have proved efficacy in the treatment of psoriasis, but the disease’s complex etiology requires a multimodal therapeutic strategy. A 22-year-old male patient with persistent plaque psoriasis in the last three years presented with erythematous plaques over the back, chest, neck, legs, abdomen, scalp, and forehands. The Auspitz sign, Candle grease sign, and Koebner phenomenon were positive. The treatment plan was based on the Ayurvedic Samprapti (~pathophysiology) of Ekakushta (~plaque psoriasis). Virechana (~therapeutic purgation) along with Ayurvedic oral medicines and a wholesome dietary regimen were given. Within eight months of the treatment, the psoriatic lesions and associated signs and symptoms were healed effectively. No adverse events were reported during the course of therapy and no recurrence was noticed as of reporting the present case report. Altogether, multimodal Ayurveda treatment can be an effective and safe solution for plaque psoriasis.

Ayurveda treatment strategy in management of advanced breast cancer in elderly female- A case report with review of literature

Breast cancer is the most common malignancy among women globally and in India. The higher prevalence of advanced breast cancer (ABC) in elderly women is attributable to delayed diagnosis, lack of sufficient health care resources and high costs for conventional treatment). Also, the modern treatment very extensive for ABC cases with surgery, chemotherapy and radiotherapy with little compliance for elderly patients and mortality is mostly linked to the side-effects of these advanced treatments. We report a case of advanced breast cancer (locally advanced to axillary nodes and skeletal muscles) in 76 year-old-female patient who presented with initially with in right subscapular region and insomnia after conventional chemotherapy. She opted for complete Ayurvedic treatment over 8 months which led to complete regression of cancer and local sites. The aim of the case report is present the symptoms, treatment regimens, and dietary modifications of such a case with basic literature review on Ayurveda treatment of breast cancers.

Effect of Shashtika Shali Pinda Sweda & other Ayurvedic Intervention in Cerebral palsy: A Case Report

Cerebral palsy is a disorder that affects muscle tone, movement and motor skills (the ability to move in a coordinated and purposeful way). Cerebral Palsy cannot be correlated with any single disease or condition mentioned in Ayurveda, as it is a multi-factorial disease. The classical signs and symptoms of CP will fit into criteria of Vata Vyadhi spectrum (Vata predominant disease) like Ekangvata, Sarvangvata, Pakshaghata, Pangu, Kampavata etc and Phakkaroga. Although cerebral palsy cannot be completely cured but treatment will generally enhance a child’s abilities. Agnimandya, Amavastha and Kaphavastha should be considered while planning the line of treatment in CP cases. The selected Ayurvedic treatment modality is highly effective in relieving the signs and symptoms and thus reducing the disability in children with CP. Swedana (sudation) is the therapy that relieves the Stambha (stiffness) of the body, mitigate feeling of Guruta (heaviness) and Sheeta (feeling of cold). Shastika shali panda sweda comes under the category of Saagniseda with Snigda dravya as milk and Shalidhanya. It has Snigdha, Guru, Sthira, Sheeta, Tridoshaghna and Brimhanaguna. In this article, an attempt to treat a child with spastic diplegia using multiple Ayurveda treatment modalities. At the end of one year of treatment, Panchkarma procedures along with internal medication resulted in 15-20% improvement in the overall effect of therapy.

Clinical Evaluation of Two Ayurveda Treatment Regimes in Ekakustha

Psoriasis is one of the most dreadful dermatological conditions affecting 3.5% of population of the world and in India prevalence of Psoriasis varies from 0.44% to 2.88%. Males and females are equally predisposed and all age groups are affected. Psoriasis is common genetically determined inflammatory skin disorder of unknown cause which in its most usual form is characterized by well demarcated raised red swelling patch that preferentially localize to extensor surfaces, which is compared to Ekakustha. Acharya particularly emphasized Shodhan Chikitsa in the Kushtha treatment because of its repeated relapse. Shodhan therapy has obvious advantages over Shaman therapy because it overcomes repeated relapses. Twenty patients were selected and randomly divide into two groups with 10 patients in each group. In group A Vaman with Krutvedhan followed by Virechana and Basti was given. In group B Vaman with Madanphala followed by Virechana and Basti was given. Comparing the symptomatic improvement in all two groups it was found that average percentage of relief was slightly higher in Group B (Vaman with Madanphala) in comparison to Group A (Vaman with Krutvedhan). The average reduction of PASI score is more in group B. but statistically the difference between the effects of two therapies is insignificant, so it is concluded that Shodhana Karma gives significant results in subjective and objective parameters of Ekakushtha irrespective of the medicine used in Vamana Karma.

Ayurvedic Treatment Protocol in the Management of Kapha Vataja Gridhrasi- A Case Report

The disease wherein the Kandara which passes through the Parshni (the region below Gulphabhaga) towards the Pratyanguli gets affected by Vata dosha resulting in difficulty in Prasarana of Sakthi (region starting from Gulpha and ending in Vitapa) is called Grdhrasi. Grdhrasi is of two types Vataja and Vatakaphaja, hence the factors that cause the vitiation of Kapha should also be considered in case of Vata kaphaja Grdhrasi. Patient was a 38 years old female Software engineer, complaints of severe low backache radiating to right lower limb which is continuous for last 3 weeks. Since 4 years she is under allopathic medication and she is getting only temporary relief. Since the patient was having Kapha vataja gridhrasi, along with Sama lakshana, Rukshana was the initial line of management, followed by Snigda sweda and Erandamooladi niruha basti. The case study suggested that an Avastha anusara ayurveda treatment will be effective in managing Kapha vataja gridhrasi. Ayurveda treatments can arrest the progress of the disease. Kaphavatahara treatments were adopted mainly focusing on Kapha. With a thorough understanding of Dosha involved we can manage the complex conditions like Gridhrasi.

Efficacy of Ayurveda Interventions in Protein Energy Malnutrition in Children: A Systematic Review and Meta-Analysis

According to United Nations International Children's Emergency Fund (UNICEF), in India, around 46 percent of all children below the age of three are too small, and 35.7% are underweight and come under MAM (Moderate Acute Malnutrition). Protein Energy Malnutrition (PEM) can be correlated with Karshya, Balashosha, Phakka, Parigarbhika, Sushka Revati, and Apatarpanjanya Vyadhi based on similar clinical features. Multiple evidencebased clinical studies are conducted in this sector, but no comparative conclusion of results or systemic review is accomplished. The study aims to evaluate and compare Ayurveda interventions' efficacy in managing children's protein energy malnutrition and to assess the effect of Ayurveda Interventions on weight gain and serum protein values in children suffering from PEM. This systemic review was conducted according to the guidelines of the Cochrane Handbook of Systemic review of interventions and is reported following the Preferred Reporting Guideline for Systemic review and meta-analysis guidelines (PRISMA). All study groups showed significant p values within the group and insignificant p values in the fixed random effect model. Though the p-value is insignificant between the groups, one group among the four shows better results in the fixed effect model. In the primary outcome of weight, group 3, i.e., the category of drugs having Bruhana and Pachana combination, shows better results than other groups in the fixed effect model. In the outcome of serum protein values, BMI, and Head circumference, group 4, i.e., drugs with only Bruhana properties, show better results than other groups. Based on this review, few policies or treatment protocols can be hypothesized for managing PEM at the national level. The Ayurveda intervention combinations have worked better because they work on multiple aetiological factors and biological variations in PEM in Children.

Integrative Strategy with Ayurveda and Electro-Acupuncture in Hemifacial Spasm: a Case Report

We report a primary hemifacial spasm that started four years ago with sudden twitching of the face towards the right side. It was diagnosed as a hemifacial spasm by a neurologist and prescribed with Zeptol 100 mg 0.5 tablet BID for two weeks, followed by two sittings of Botox injection in a gap of 1 year. A year later, it reappeared more severely, driving her towards an integrative treatment modality. Ayurveda treatments including Nasya, Ksheera dhooma, internal medications, and Rasona navaneetha prayoga were administered. GV20, GB14, EX-HN5, ST3, ST4, ST6, TE17, LI4, and GB34 were selected for electro-acupuncture. The scores of hemifacial spasm grading and quality of life scale were 9 and 20 (before), 6 and 16 (after treatment), and 4 and 10 (follow-up after six months), respectively. This integrative approach was safe and has shown an improvement in hemifacial spasm.

Ayurvedic management of Ulcerative Colitis: A Case Study

Introduction: Ulcerative colitis (UC) is an inflammatory bowel disease with remitting and relapsing pattern in which long term or repeated cortico-steroid and biological medicines are only available treatment which have limited effect and carrying many serious adverse effects.[1] Purpose: Inflammation invariably involves the rectum (proctitis) and may spread proximally to involve sigmoid colon (procto-sigmoiditis) and in some cases, it involves whole colon (pancolitis). The major symptom of ulcerative colitis is blood in stools.[2] In conventional medicine there is no any treatment which give completely relief or surgical treatment. But in Ayurveda treatment approaches are helpful in such diseases. With the changing demand and awareness among these days, the role of Ayurveda is an emerging reality. Brief case history: A 36-year-old male pharmaceutical manager by occupation at Canada, patient came to the P D Patel Ayurveda Hospital, Nadiad with confirmed diagnosis of ulcerative colitis since 10 years. He has more than 10 times stool frequency in which average 5 frequencies contain blood and mucus. Before he came to us, he took conventional medicine for the same complaints but didn’t get any satisfactory result. He was hospitalized and treated with Basti and oral Ayurvedic medicines for one month period. His stool frequency reduced significantly in a day without bleeding and mucus. After one month of treatment, he is continuing oral medicine at OPD. Now he has one or two frequencies with normal consistency of stool without blood or slime. His haemoglobin level was also increased significantly. Result: He got an excellent result with complete relief from all symptoms as well as marked reduction in objective criteria (lab investigation) within 1 month.

Review article on the Gridharasi (Sciatica)

Low back pain is one of the most common ailments in today's modern age affecting 75% to 80% of the population it affects people of all ages, from child to old age. Among the various causes of lower back pain, sciatica (Ghrdasi) can be considered as the most common cause. Sciatica (Ghrdasi) is pain in the sciatic nerve that runs from the lower back down one or both legs. The intensity of pain in sciatica is so extreme that it interferes with the person's daily activities. In Gridharasi, the pain starts from the waist and goes to the lower back (back), thigh (thigh), janu (knee), thigh and foot (feet) and the pain may also be associated with stiffness and heaviness of the body. In Ayurveda treatment, Panchakarma process along with proper yoga asana can be used to manage Gridharasi disease.

Management of albuminuria and dysuria through Ayurveda interventions in a patient with crossed renal ectopia

Albuminuria is one of the most typical symptoms when there are derangements in the kidney functions, which may damage the kidney’s functional units, that is, nephrons. This study presents a case of a patient suffering from albuminuria who was diagnosed with crossed renal ectopia, that is, fused right kidney to the left side. A 61-year-old male patients suffered from generalized body weakness, proteinuria, disturbed sleep, and dysuria. Because of dysuria, the patient needed catheterization every fortnight. The patient had no history of addiction to smoking and alcohol. The patient had no history of diabetes mellitus, hypertension, or systemic disease except pulmonary tuberculosis 30 years back. The kidney function test, urine routine, and microscopy examination revealed albuminuria, the presence of bacteria, and elevated serum uric acid level. Crossed renal ectopia was diagnosed through a computed tomography examination. From an Ayurveda perspective, the diagnosis of Kaphaja Meha was based on the patient’s complaints, such as increased frequency of micturition and hazy/turbid urine. The treatment plan was made according to the management of Kaphaja Meha. Chandraprabha Vati, Punarnava Asava, Punarnava capsule, and SG syrup—an Ayurvedic formulation, were prescribed along with the dietary regimen. Follow-up was done seven times within 9 months. The medications and dose were altered according to the patient’s condition. The patient’s condition improved symptomatically. After the Ayurvedic intervention for 9 months and 23 days, albumin was absent in urine; serum uric acid became 4.90 mg/dL, and the glomerular filtration rate increased to 88/mL/min/1.73 m2. The patient had normal urination without needing catheterization. The case study results indicate that Ayurveda interventions can manage albuminuria and dysuria in patients with crossed renal ectopia.

Ayurveda management of primary infertility associated with hypothyroidism and hyperprolactinemia: A case report

Abstract: Hypothyroidism and hyperprolactinemia adversely affect the fertility potential of women by impairing ovulatory function. There is a high prevalence of hypothyroid-associated hyperprolactinemia in infertility. Long-standing hypothyroidism promotes hyperprolactinemia which leads to irregular periods, and anovulation and ultimately results in infertility. This is a case report of the primary infertility of a couple married for seven years. The female partner had anovulatory cycles with elevated levels of Thyroid-Stimulating Hormone (TSH) and prolactin. Ayurveda treatment was planned in this case to evaluate its role to address hormonal imbalance, ensuring regular ovulation, and thereby helping to have a normal pregnancy. Based on the parameters of Ayurvedic Science, this case was diagnosed as Vandhyatva (~infertility), which was treated with both internal medicines and external therapies including Shodhana (~bio cleansing therapy) and Shamana chikitsa (~therapy which is aimed at mitigating the disease by pacifying Dosha). After the treatment, TSH was reduced from 14.99 to 4.0 μIU/mL and the prolactin level was reduced from 47.23 to 13 ng/mL. The intervention resulted in conception within three months, and she delivered a full-term female baby.