Aviat Space Environ Med Research Articles

Microgravity and cardiac atrophy: no sex discrimination

mans’ continued initiative in space exploration will tax the human body, including the cardiovascular system. This system is exquisitely sensitive to loading conditions and neurohormonal stimuli and is adapted to function in normal gravitational environments (1 G). Both mechanical (muscle and

Brain Arteriovenous Malformations

Although intracranial hemorrhages,1 interest in brain arteriovenous malformations (BAVMs) is expanding from its origins as a neuropathologic curiosity to the treatment-oriented specialties of neurological surgery, interventional neuroradiology, radiosurgery/therapy, and clinical neurology, and is even emerging as a subject in neuroepidemiology. Recent insights from uncontrolled series: argue for some genetic derangements in the origin of some of the lesions2,3; have revised some issues of pathophysiology4–7; track the risk of hemorrhage over time8; suggest the risk for hemorrhage can be predicted by vascular factors discoverable by noninvasive or minimally invasive imaging9,10; indicate many initial hemorrhage syndromes are mild,11 more so than that caused by non-BAVM parenchymal or aneurysmal subarachnoid hemorrhages12; have reassessed the outcomes from intervention in a variety of forms after initial hemorrhage13–15; raise questions concerning the safety and …

Medical Errors and Emergency Medicine: Will the Difficult Questions Be Asked, and Answered?

Academic Emergency MedicineVolume 10, Issue 8 p. 910-911 Free Access Medical Errors and Emergency Medicine: Will the Difficult Questions Be Asked, and Answered? James A. Feldman MD, Corresponding Author James A. Feldman MD(jfeldman@bu.edu), Department of Emergency Medicine, Boston Medical Center, Boston University School of Medicine, Boston, MASearch for more papers by this author James A. Feldman MD, Corresponding Author James A. Feldman MD(jfeldman@bu.edu), Department of Emergency Medicine, Boston Medical Center, Boston University School of Medicine, Boston, MASearch for more papers by this author First published: 28 June 2008 https://doi.org/10.1197/aemj.10.8.910Citations: 10AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1 Shapiro MJ, Croskerry P, Fisher S. Profiles in patient safety: sidedness error. Acad Emerg Med. 2002; 9: 326– 9. 2 Luna TD. Air traffic controller shiftwork: what are the implications for aviation safety? A review. Aviat Space Environ Med. 1997; 68: 69– 79. 3 Luna TD, French J, Mitcha JL. A study of USAF air traffic controller shiftwork: sleep, fatigue, activity, and mood analyses. Aviat Space Environ Med. 1997; 68: 18– 23. 4 Smith L, Folkard S, Tucker P, Macdonald I. Work shift duration: a review comparing eight hour and 12 hour shift systems. Occup Environ Med. 1998; 55: 217– 29. 5 Spurgeon A, Harrington JM, Cooper CL. Health and safety problems associated with long working hours: a review of the current position. Occup Environ Med. 1997; 54: 367– 75. 6 Kuhn G. Circadian rhythm, shift work, and emergency medicine. Ann Emerg Med. 2001; 37: 88– 98. Citing Literature Volume10, Issue8August 2003Pages 910-911 ReferencesRelatedInformation

Raised leptin concentrations at high altitude associated with loss of appetite

Loss of appetite is a common symptom of acute mountain sickness (AMS). 1 Sampson JB Cymerman A Burse RL Maher JT Rock PB Procedures for the measurement of acute mountain sickness. Aviat Space Environ Med. 1983; 54: 1063-1073 PubMed Google Scholar Weight loss, induced by increased energy expenditure and reduced food intake, occurs during prolonged exposure to altitudes above 5000 m. Loss of fat accounts for up to 74% of this weight loss. 2 Westerterp KR Kayser B Wouters L Le-Trong JL Richalet JP Energy balance at high altitude of 6542 m. J Appl Physiol. 1994; 77: 862-866 PubMed Google Scholar Because leptin is a key mediator in the neuroendocrine regulation of energy homoeostasis and appetite, 3 Auwerx J Staels B Leptin. Lancet. 1998; 351: 737-742 Summary Full Text Full Text PDF PubMed Scopus (521) Google Scholar we investigated the effect of hypobaric hypoxia at high altitude on serum leptin concentrations, using a sensitive and specific method of measurement. 4 Tschöp M Wu Z Bidlingmaier M Heiman ML Strasburger CJ Generation of monoclonal antibodies and establishment of a sensitive sandwich immunoassay for the measurement of human serum leptin. Exp Clin Endocrinol Diabetes. 1998; 106: 40 Google Scholar

Rhinocerebral Mucormycosis

Rhinocerebral Mucormycosis

Effects of slow ascent to 4,559 M on fluid homeostasis: Bartsch P, Pfluger N, Audetat M, et al Aviat Space Environ Med 62:105–110 Feb 1991

Effects of slow ascent to 4,559 M on fluid homeostasis: Bartsch P, Pfluger N, Audetat M, et al Aviat Space Environ Med 62:105–110 Feb 1991

Use of phenytoin in the prevention of motion sickness: Chelen W, Kabrisky M, Hatsell C, et al Aviat Space Environ Med 61:1022–1025 Nov 1990

Use of phenytoin in the prevention of motion sickness: Chelen W, Kabrisky M, Hatsell C, et al Aviat Space Environ Med 61:1022–1025 Nov 1990

A survey of advanced trauma life support procedures being performed by physicians and nurses used on hospital aeromedical evacuation services : Thomas F, Clemmer TP, Orme JF. Aviat Space Environ Med 1985; 56:1213–1215

A survey of advanced trauma life support procedures being performed by physicians and nurses used on hospital aeromedical evacuation services : Thomas F, Clemmer TP, Orme JF. Aviat Space Environ Med 1985; 56:1213–1215

Non-steroidal analgesic and anti-inflammatory agents.

3 Nicholson AN, Stone BM. Sleep and wakefulness handbook for flight medical officers. Neuilly-sur-Seine, France: NATO Advisory Group for Aerospace Research and Development, 1982; AGARDograph No 270. 4 Fiorica V, Higgins EA, Iampietro PF, Lategola MT, Davis AW. Phy? siological responses of men during sleep deprivation. J Appl Physiol 1968;24:167-76. 5 Mills JN, Minors DS, Waterhouse JM. The circadian rhythms of human subjects without timepieces or indications of the alteration of day and night. J Physiol (Lond) 1974;240:567-94. 8 McFarland RA. Influence of changing time zones on air crews and passen? gers. Aerospace Med 1974;45:648-58. 7 Elliot AN, Mills JN, Minors DS, Waterhouse JM. Effect of simulated time zone shifts upon plasma corticosteroid rhythms. J Physiol (Lond) 1971;217:50P. 8 Arendt J, Marks V. Physiological changes underlying lag. Br Med J 1982;284:144-6. ? Desir D, Van Cauter E, Fang VS, et al. Effects of jet lag on hormonal patterns. I. Procedures, variations in total plasma proteins and dis? ruption of adrenocorticotropin-cortisol periodicity. J Clin Endocrinol Metab 1981;52:628-41. 10 Klein KE, Wegmann HM. Significance of circadian rhythms in aerospace operations. Neuilly-sur-Seine, France: NATO Advisory Group for Aerospace Research and Development, 1980; AGARDograph No 247. 11 Mohler SR. Physiological index as an aid in developing airline pilot scheduling patterns. Aviat Space Environ Med 1976;47:238-47. 12 Alter JD, Mohler SR. Preventive medicine aspects and health promotion programs for flight attendants. Aviat Space Environ Med 1980 ;51:168-75. 13 Civil Aviation Authority. Air navigation?the order and the regulations. London: Civil Aviation Authority, 1981; CAP 393 (2nd ed) schedule 5, scale K: sect 1/76-1/77. 14 Norris W. The unsafe sky. London: Arrow Books, 1981:106-24. 15 Mohler SR. Air crash survival: injuries and evacuation toxic hazards. Aviat Space Environ Med 1975;46:86-8. 16 Pollard DW. Injuries in air transport emergency evacuations. Aviat Space Environ Med 1979;50:943-7.